Synthetically defined glycoprotein vaccines: current status and future directions. (Q39375701)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25893089%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

title

Synthetically defined glycoprotein vaccines: current status and future directions (English)

1 reference

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6 March 2020

4

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6 March 2020

Gonçalo J. L. Bernardes

6

1 reference

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6 March 2020

author name string

Roberto Adamo

1

1 reference

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6 March 2020

Alberto Nilo

2

1 reference

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6 March 2020

Bastien Castagner

3

1 reference

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6 March 2020

Francesco Berti

5

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6 March 2020

publication date

16 May 2013

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6 March 2020

1 reference

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6 March 2020

volume

4

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6 March 2020

page(s)

2995-3008

1 reference

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6 March 2020

issue

8

1 reference

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The development of synthetic antitumour vaccines from mucin glycopeptide antigens

6 March 2020

cites work

1 reference

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Prospects in the total synthesis of protein therapeutics.

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Metal complex catalysis in living biological systems

11 September 2017

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Designing a new antifungal glycoconjugate vaccine

11 September 2017

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Automated synthesis of sialylated oligosaccharides

11 September 2017

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Chemical synthesis and immunological evaluation of the inner core oligosaccharide of Francisella tularensis

11 September 2017

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The design of semi-synthetic and synthetic glycoconjugate vaccines

11 September 2017

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Stereoselective assembly of complex oligosaccharides using anomeric sulfonium ions as glycosyl donors

11 September 2017

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Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

11 September 2017

1 reference

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Toward automated oligosaccharide synthesis

11 September 2017

1 reference

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Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

11 September 2017

1 reference

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A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design

11 September 2017

1 reference

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A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

11 September 2017

1 reference

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Protein glycoengineering enabled by the versatile synthesis of aminooxy glycans and the genetically encoded aldehyde tag

11 September 2017

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Enzymes in the synthesis of glycoconjugates

11 September 2017

1 reference

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Efficacy of a conjugate vaccine containing polymannuronic acid and flagellin against experimental Pseudomonas aeruginosa lung infection in mice.

11 September 2017

1 reference

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NGcGM3 ganglioside: a privileged target for cancer vaccines

11 September 2017

1 reference

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A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity

11 September 2017

1 reference

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Glycoconjugate vaccines and immune interference: A review

11 September 2017

1 reference

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Preparation, characterization and immunogenicity of HIV-1 related high-mannose oligosaccharides-CRM197 glycoconjugates

11 September 2017

1 reference

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Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds

11 September 2017

1 reference

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Carbohydrate vaccines: developing sweet solutions to sticky situations?

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Adding new chemistries to the genetic code

11 September 2017

1 reference

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Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research

11 September 2017

1 reference

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How bacterial carbohydrates influence the adaptive immune system

11 September 2017

1 reference

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Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strains

11 September 2017

1 reference

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Enzymatic transglycosylation for glycoconjugate synthesis

11 September 2017

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Immunotherapy for cancer: synthetic carbohydrate-based vaccines

11 September 2017

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Bioorthogonal chemistry: fishing for selectivity in a sea of functionality

11 September 2017

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From synthesis to biologics: preclinical data on a chemistry derived anticancer vaccine

11 September 2017

1 reference

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Emerging methods for the production of homogeneous human glycoproteins

11 September 2017

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Combined approaches to the synthesis and study of glycoproteins.

11 September 2017

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Glycoprotein synthesis: an update.

11 September 2017

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Toll-like receptors and cancer

11 September 2017

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An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

11 September 2017

1 reference

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Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis

11 September 2017

1 reference

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Identification of the smallest structure capable of evoking opsonophagocytic antibodies against Streptococcus pneumoniae type 14.

11 September 2017

1 reference

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Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN

11 September 2017

1 reference

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Robust immune responses elicited by a fully synthetic three-component vaccine

11 September 2017

1 reference

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Effect of the nonreducing end of Shigella dysenteriae type 1 O-specific oligosaccharides on their immunogenicity as conjugates in mice

11 September 2017

1 reference

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Oligosaccharide assembly by one-pot multi-step strategy

11 September 2017

1 reference

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Regioselective one-pot protection of carbohydrates

11 September 2017

1 reference

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Glycosylation in cellular mechanisms of health and disease

11 September 2017

1 reference

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Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.

11 September 2017

1 reference

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A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems

11 September 2017

1 reference

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On the nature of the multivalency effect: a thermodynamic model

11 September 2017

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Solid-phase oligosaccharide synthesis and combinatorial carbohydrate libraries

11 September 2017

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Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial

11 September 2017

1 reference

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Automated solid-phase synthesis of oligosaccharides

11 September 2017

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Protein conjugates of synthetic saccharides elicit higher levels of serum IgG lipopolysaccharide antibodies in mice than do those of the O-specific polysaccharide from Shigella dysenteriae type 1

11 September 2017

1 reference

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Expressed protein ligation: a general method for protein engineering

11 September 2017

1 reference

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Structural properties of group B streptococcal type III polysaccharide conjugate vaccines that influence immunogenicity and efficacy.

11 September 2017

1 reference

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Comparison of conjugates composed of lipopolysaccharide from Shigella flexneri type 2a detoxified by two methods and bound to tetanus toxoid

11 September 2017

1 reference

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Synthesis of proteins by native chemical ligation

11 September 2017

1 reference

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Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates

11 September 2017

1 reference

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Synthesis, characterization, and some immunological properties of conjugates composed of the detoxified lipopolysaccharide of Vibrio cholerae O1 serotype Inaba bound to cholera toxin

11 September 2017

1 reference

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Constructing proteins by dovetailing unprotected synthetic peptides: backbone-engineered HIV protease

11 September 2017

1 reference

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Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21.

11 September 2017

1 reference

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Synthesis and biological evaluation of a multiantigenic Tn/TF-containing glycopeptide mimic of the tumor-related MUC1 glycoprotein

14 September 2017

1 reference

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HPLC-assisted automated oligosaccharide synthesis

14 September 2017

1 reference

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A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic

17 June 2018

1 reference

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CHEMO-IMMUNOLOGICAL STUDIES ON CONJUGATED CARBOHYDRATE-PROTEINS : V. THE IMMUNOLOGICAL SPECIFITY OF AN ANTIGEN PREPARED BY COMBINING THE CAPSULAR POLYSACCHARIDE OF TYPE III PNEUMOCOCCUS WITH FOREIGN PROTEIN.

17 June 2018

1 reference

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Highly efficient chemoenzymatic synthesis of naturally occurring and non-natural alpha-2,6-linked sialosides: a P. damsela alpha-2,6-sialyltransferase with extremely flexible donor-substrate specificity

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Induction of meningococcal group B polysaccharide-specific IgG antibodies in mice by using an N-propionylated B polysaccharide-tetanus toxoid conjugate vaccine.

17 June 2018

1 reference

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Thiol-yne radical reaction mediated site-specific protein labeling via genetic incorporation of an alkynyl-L-lysine analogue.

17 June 2018

1 reference

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Automated solid phase synthesis of oligoarabinofuranosides

21 August 2018

1 reference

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Rewriting the bacterial glycocalyx via Suzuki-Miyaura cross-coupling.

21 August 2018

1 reference

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Phosphorylation of the synthetic hexasaccharide repeating unit is essential for the induction of antibodies to Clostridium difficile PSII cell wall polysaccharide

21 August 2018

1 reference

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Direct radiolabelling of proteins at cysteine using [18F]-fluorosugars.

21 August 2018

1 reference

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Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins

21 August 2018

1 reference

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Carrier induced epitopic suppression of antibody responses induced by virus-like particles is a dynamic phenomenon caused by carrier-specific antibodies

21 August 2018

1 reference

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Phosphate-assisted peptide ligation.

21 August 2018

1 reference

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Rational design and immunogenicity of liposome-based diepitope constructs: application to synthetic oligosaccharides mimicking the Shigella flexneri 2a O-antigen.

21 August 2018

1 reference

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Toward solution-phase automated iterative synthesis: fluorous-tag assisted solution-phase synthesis of linear and branched mannose oligomers

21 August 2018

1 reference

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Allyl sulfides are privileged substrates in aqueous cross-metathesis: application to site-selective protein modification.

21 August 2018

1 reference

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Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins.

21 August 2018

1 reference

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Automated solid-phase synthesis of protected oligosaccharides containing beta-mannosidic linkages

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Exploring the structural diversity of mammalian carbohydrates ("glycospace") by statistical databank analysis

21 August 2018

1 reference

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De novo asymmetric synthesis of the anthrax tetrasaccharide by a palladium-catalyzed glycosylation reaction

21 August 2018

1 reference

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Sugar-assisted glycopeptide ligation

21 August 2018

1 reference

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Tyrosine-selective protein alkylation using pi-allylpalladium complexes.

21 August 2018

1 reference

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A fully synthetic therapeutic vaccine candidate targeting carcinoma-associated Tn carbohydrate antigen induces tumor-specific antibodies in nonhuman primates

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Vaccination of small cell lung cancer patients with polysialic acid or N-propionylated polysialic acid conjugated to keyhole limpet hemocyanin.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

The upper limit for the size of the human antidextran combining site

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Protein assembly by orthogonal chemical ligation methods

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Solid-phase synthesis of beta-mannosides

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4396375

Towards a Fully Synthetic Carbohydrate-Based Anticancer Vaccine: Synthesis and Immunological Evaluation of a Lipidated Glycopeptide Containing the Tumor-Associated Tn Antigen

21 August 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3SC50862E

Perorally active nanomicellar formulation of quercetin in the treatment of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3SC50862E

Conjugation of synthetic N-acetyl-lactosamine to azide-containing proteins using the Staudinger ligation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3SC50862E

Chemoenzymatic synthesis of differentially protected 3-deoxysugars

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC3SC50862E

GD3 vaccines for melanoma: superior immunogenicity of keyhole limpet hemocyanin conjugate vaccines

21 January 2018

1 reference

12 December 2020

Oligosaccharide Synthesis on a Fluorous Support

1 reference

12 December 2020

Efficient synthesis of an alpha(2,9) trisialic acid by one-pot glycosylation and polymer-assisted deprotection

1 reference

12 December 2020

Automated solid-phase synthesis of β-mannuronic acid alginates

1 reference

12 December 2020

Gold nanoparticles as carriers for a synthetic Streptococcus pneumoniae type 14 conjugate vaccine

1 reference

12 December 2020

Thomsen-Friedenreich (TF) antigen as a target for prostate cancer vaccine: clinical trial results with TF cluster (c)-KLH plus QS21 conjugate vaccine in patients with biochemically relapsed prostate cancer

1 reference

12 December 2020

Site-Selective Traceless Staudinger Ligation for Glycoprotein Synthesis Reveals Scope and Limitations

1 reference

12 December 2020

The Direct Formation of Glycosyl Thiols from Reducing Sugars Allows One-Pot Protein Glycoconjugation

1 reference

12 December 2020

A synthetic conjugate polysaccharide vaccine against Haemophilus influenzae type b

1 reference

12 December 2020

T-cell recognition of tumor-associated carbohydrates: the nature of the glycan moiety plays a decisive role in determining glycopeptide immunogenicity

1 reference

12 December 2020

The unique solution structure and immunochemistry of the Candida albicans beta -1,2-mannopyranan cell wall antigens

1 reference

12 December 2020

Thiyl glycosylation of olefinic proteins: S-linked glycoconjugate synthesis

1 reference

12 December 2020

A “Tag-and-Modify” Approach to Site-Selective Protein Modification

1 reference

12 December 2020

A polyvalent vaccine for high-risk prostate patients: "are more antigens better?"

1 reference

12 December 2020

Chemoselective amide ligations by decarboxylative condensations of N-alkylhydroxylamines and alpha-ketoacids

1 reference

12 December 2020

Synthesis of the Lewis a trisaccharide based on an anomeric silyl fluorous tag

1 reference

12 December 2020

Selenenylsulfide-Linked Homogeneous Glycopeptides and Glycoproteins: Synthesis of Human “Hepatic Se Metabolite A”

1 reference

12 December 2020

Peptide Ligations Accelerated byN-Terminal Aspartate and Glutamate Residues

1 reference

12 December 2020

A Coordinated Synthesis and Conjugation Strategy for the Preparation of Homogeneous Glycoconjugate Vaccine Candidates

1 reference

12 December 2020

Identifiers

DOI

10.1039/C3SC50862E

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25893089%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25893089%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference