ZRF1 controls oncogene-induced senescence through the INK4-ARF locus (Q39325305)

11 September 2017

ZRF1 controls oncogene-induced senescence through the INK4-ARF locus (English)

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J D Ribeiro

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11 September 2017

A Mas

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A Gutierrez

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N M Luis

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S Mejetta

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H Richly

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S A Benitah

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W M Keyes

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language of work or name

English

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publication date

25 June 2012

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2161-2168

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https://scigraph.springernature.com/pub.10.1038/onc.2012.241

11 September 2017

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cites work

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p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

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Chromatin: a molecular interface between cancer and aging

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Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus

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SWI/SNF mediates polycomb eviction and epigenetic reprogramming of the INK4b-ARF-INK4a locus

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Polycomb CBX7 has a unifying role in cellular lifespan

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

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Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus

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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

21 January 2018

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Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

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DDB1-CUL4 and MLL1 mediate oncogene-induced p16INK4a activation

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Epigenetics and senescence: learning from the INK4-ARF locus.

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Transcriptional activation of polycomb-repressed genes by ZRF1

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Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro

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Distinct versus redundant properties among members of the INK4 family of cyclin-dependent kinase inhibitors

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Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

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Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

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MIDA1, a protein associated with Id, regulates cell growth

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CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis

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Multistep skin cancer in mice as a model to study the evolution of cancer cells

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Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor

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Identification of novel M phase phosphoproteins by expression cloning

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A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.

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Motif module map reveals enforcement of aging by continual NF-kappaB activity

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p63 deficiency activates a program of cellular senescence and leads to accelerated aging

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c-Myc promotes differentiation of human epidermal stem cells

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

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The flip side of the coin: role of ZRF1 and histone H2A ubiquitination in transcriptional activation

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Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

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31 March 2020

Identifiers

DOI

10.1038/ONC.2012.241

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Dimensions Publication ID

11 September 2017

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