Androgen receptor primes prostate cancer cells to apoptosis through down-regulation of basal p21 expression (Q39243442)

20 February 2018

title

Androgen receptor primes prostate cancer cells to apoptosis through down-regulation of basal p21 expression (English)

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20 February 2018

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1 reference

Yuting Lin

1

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20 February 2018

Ziyan Lu

series ordinal

2

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20 February 2018

John Kokontis

series ordinal

3

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20 February 2018

Jialing Xiang

series ordinal

4

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20 February 2018

language of work or name

English

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publication date

15 November 2012

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20 February 2018

Biochemical and Biophysical Research Communications

published in

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20 February 2018

volume

430

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20 February 2018

issue

1

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20 February 2018

page(s)

289-293

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20 February 2018

Pirh2 RING-finger E3 ubiquitin ligase: its role in tumorigenesis and cancer therapy

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The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation

15 June 2018

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Pirh2 E3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis

15 June 2018

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Proteasomal degradation unleashes the pro-death activity of androgen receptor

15 June 2018

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Androgen via p21 inhibits tumor necrosis factor alpha-induced JNK activation and apoptosis

15 June 2018

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Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains

15 June 2018

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PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

15 June 2018

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Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer

15 June 2018

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Androgen and its receptor promote Bax-mediated apoptosis

15 June 2018

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Structure and function of steroid receptor AF1 transactivation domains: induction of active conformations

15 June 2018

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Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity

15 June 2018

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Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

15 June 2018

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Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

15 June 2018

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Lentivirus-delivered stable gene silencing by RNAi in primary cells

15 June 2018

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The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

15 June 2018

1 reference

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The role of androgens and the androgen receptor in prostate cancer

15 June 2018

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Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.

15 June 2018

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Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites

15 June 2018

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Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

15 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Structural analysis of complementary DNA and amino acid sequences of human and rat androgen receptors

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Molecular cloning and structural analysis of complementary DNA of human and rat androgen receptors

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Pirh2 promotes ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

P21Cip1/WAF1 downregulation is required for efficient PCNA ubiquitination after UV irradiation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

IGF-1 activates p21 to inhibit UV-induced cell death.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Apoptosis-inducing levels of UV radiation and proteasome inhibitors produce opposite effects on p21(WAF1) in human melanoma cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5702546

Differential activation of p53 targets in cells treated with ultraviolet radiation that undergo both apoptosis and growth arrest

21 August 2018

1 reference

12 December 2020

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

12 December 2020

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor

1 reference

12 December 2020

Apoptosis: translating theory to therapy for prostate cancer

1 reference

12 December 2020

10.1016/J.BBRC.2012.10.135

Identifiers

DOI

1 reference

20 February 2018

PMCID

5702546

1 reference

20 February 2018

PubMed ID

23159636

1 reference

20 February 2018