IGF-1 activates p21 to inhibit UV-induced cell death. (Q48028666)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642873%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

IGF-1 activates p21 to inhibit UV-induced cell death (English)

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1 November 2019

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2

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1 November 2019

author name string

Stephen A Murray

series ordinal

1

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1 November 2019

Ling Gu

series ordinal

3

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1 November 2019

Zhi-Xiong Jim Xiao

series ordinal

4

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1 November 2019

language of work or name

English

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publication date

1 March 2003

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1 November 2019

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1 November 2019

volume

22

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1 November 2019

issue

11

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1 November 2019

page(s)

1703-1711

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206327

1 November 2019

exact match

0 references

cites work

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

1 reference

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Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

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A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

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Insulin, insulin-like growth factor-I (IGF-I), IGF binding proteins, their biologic interactions, and colorectal cancer

21 January 2018

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21 January 2018

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Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons.

21 January 2018

1 reference

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Live or let die: the cell's response to p53

21 January 2018

1 reference

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Ultraviolet radiation down-regulates expression of the cell-cycle inhibitor p21WAF1/CIP1 in human cancer cells independently of p53.

21 January 2018

1 reference

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Regulation of p53 function

21 January 2018

1 reference

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Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

21 January 2018

1 reference

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7 January 2021

Phosphorylation of HDM2 by Akt.

1 reference

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7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

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7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

1 reference

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7 January 2021

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Regulation of p53 in response to DNA damage

1 reference

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7 January 2021

Coordinate control of muscle cell survival by distinct insulin-like growth factor activated signaling pathways

1 reference

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7 January 2021

Insulin-like growth factor-mediated muscle cell survival: central roles for Akt and cyclin-dependent kinase inhibitor p21

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7 January 2021

Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Mechanisms of switching on p53: a role for covalent modification?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

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7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

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7 January 2021

The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Surfing the p53 network

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206327

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206327

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12642873%20AND%20SRC:MED&resulttype=core&format=json

release_xfl2xtr5jjaajed3rjas5273ey

1 November 2019

Fatcat ID

0 references

1 reference