Rapamycin induces apoptosis when autophagy is inhibited in T-47D mammary cells and both processes are regulated by Phlda1. (Q39214034)

10 September 2017

Rapamycin induces apoptosis when autophagy is inhibited in T-47D mammary cells and both processes are regulated by Phlda1. (English)

1 reference

10 September 2017

0 references

1 reference

Chern Ein Oon

3

0 references

author name string

Ahmed Ismail Hassan Moad

series ordinal

1

1 reference

PubMed ID

23300026

10 September 2017

Tengku Sifzizul Tengku Muhammad

series ordinal

2

1 reference

PubMed ID

23300026

10 September 2017

Mei Lan Tan

series ordinal

4

1 reference

10 September 2017

1 July 2013

1 reference

Cell Biochemistry and Biophysics

10 September 2017

1 reference

10 September 2017

66

1 reference

10 September 2017

567-587

1 reference

10 September 2017

3

1 reference

https://scigraph.springernature.com/pub.10.1007/s12013-012-9504-5

10 September 2017

0 references

cites work

Autophagy as a regulated pathway of cellular degradation

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy: highlighting a novel player in the autoimmunity scenario

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Growth arrest and non-apoptotic programmed cell death associated with the up-regulation of c-myc mRNA expression in T-47D breast tumor cells following exposure to Epipremnum pinnatum (L.) Engl. hexane extract.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Regulation and role of autophagy in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy in the eukaryotic cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Molecular machinery of autophagosome formation in yeast, Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Ultrastructural and immunocytochemical characterization of autophagic vacuoles in isolated hepatocytes: effects of vinblastine and asparagine on vacuole distributions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Purification and characterization of autophagosomes from rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagic and apoptotic response to stress signals in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The role of autophagy in cancer development and response to therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy: in sickness and in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Death by design: apoptosis, necrosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The pleiotropic role of autophagy: from protein metabolism to bactericide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy in health and disease: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy as a cell death and tumor suppressor mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy as a therapeutic target in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

TOR, a central controller of cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The target of rapamycin (TOR) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Atg101, a novel mammalian autophagy protein interacting with Atg13

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

To die or not to die: that is the autophagic question

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Tor, a phosphatidylinositol kinase homologue, controls autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Effects of STAT3 gene silencing and rapamycin on apoptosis in hepatocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Rapamycin inhibits proliferation of estrogen-receptor-positive breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy in metazoans: cell survival in the land of plenty

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

A calpain-like protease inhibits autophagic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Autophagy contributes to caspase-independent macrophage cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Inhibition of macroautophagy triggers apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Cell death: critical control points

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Apoptosis. Its significance in cancer and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Cell death: the significance of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Apoptosis and autophagy function cooperatively for the efficacious execution of programmed nurse cell death during Drosophila virilis oogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

In situ detection of starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Crystallization and preliminary X-ray analysis of Atg10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The ATG12-conjugating enzyme ATG10 Is essential for autophagic vesicle formation in Arabidopsis thaliana

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Stimulation of ATG12-ATG5 conjugation by ribonucleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The structure of nucleosome assembly protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Genes specifically expressed at growth arrest of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Growth arrest in human T-cells is controlled by the non-coding RNA growth-arrest-specific transcript 5 (GAS5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Inhibition of human T-cell proliferation by mammalian target of rapamycin (mTOR) antagonists requires noncoding RNA growth-arrest-specific transcript 5 (GAS5).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Cell cycle regulated transport controlled by alterations in the nuclear pore complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Nucleocytoplasmic transport in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Significant proportions of nuclear transport proteins with reduced intracellular mobilities resolved by fluorescence correlation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Crosstalk between the actin cytoskeleton and Ran-mediated nuclear transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

c-myc induces autophagy in rat 3Y1 fibroblast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Cleavage of rabaptin-5 blocks endosome fusion during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Inhibition of protein synthesis by the T cell receptor-inducible human TDAG51 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

A proline- and glutamine-rich protein promotes apoptosis in neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Inactivation of the RRB1-Pescadillo pathway involved in ribosome biogenesis induces chromosomal instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Many ribosomal protein genes are cancer genes in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

Toxin-dependent utilization of engineered ribosomal protein L3 limits trichothecene resistance in transgenic plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12013-012-9504-5

10.1007/S12013-012-9504-5

21 January 2018

Identifiers

DOI

1 reference

10 September 2017

1 reference

PubMed ID

23300026