The Role of the Transcriptional Response to DNA Replication Stress. (Q39159931)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28257104%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

title

The Role of the Transcriptional Response to DNA Replication Stress (English)

1 reference

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4 April 2020

1

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4 April 2020

Robertus A M de Bruin

series ordinal

2

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4 April 2020

author name string

Anna E Herlihy

series ordinal

1

1 reference

9 September 2017

Robertus A M de Bruin

series ordinal

2

1 reference

9 September 2017

2 March 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28257104%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28257104%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

volume

8

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4 April 2020

issue

3

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Creative Commons Attribution 4.0 International

4 April 2020

copyright license

start time

2 March 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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ATR prohibits replication catastrophe by preventing global exhaustion of RPA.

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ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

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Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription

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Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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10 September 2017

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DNA replication as a target of the DNA damage checkpoint

10 September 2017

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10 September 2017

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DNA replication checkpoint promotes G1-S transcription by inactivating the MBF repressor Nrm1

10 September 2017

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The DNA replication checkpoint directly regulates MBF-dependent G1/S transcription

10 September 2017

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10 September 2017

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Regulation of DNA repair throughout the cell cycle

10 September 2017

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The DNA damage response pathways: at the crossroad of protein modifications

10 September 2017

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Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior

10 September 2017

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10 September 2017

Chromosome fragile sites

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Non-transcriptional control of DNA replication by c-Myc

10 September 2017

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PCNA, the maestro of the replication fork

10 September 2017

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Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage

10 September 2017

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Replication fork stalling at natural impediments

10 September 2017

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Modulation of cell cycle-specific gene expressions at the onset of S phase arrest contributes to the robust DNA replication checkpoint response in fission yeast

10 September 2017

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DNA damage checkpoints: from initiation to recovery or adaptation

10 September 2017

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The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

10 September 2017

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Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

10 September 2017

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Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

10 September 2017

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Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback.

10 September 2017

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SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

10 September 2017

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Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress

10 September 2017

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TopBP1 activates the ATR-ATRIP complex

10 September 2017

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Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses

10 September 2017

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Autorepression of rfx1 gene expression: functional conservation from yeast to humans in response to DNA replication arrest.

10 September 2017

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Involvement of E2F transcription factor family in cancer

10 September 2017

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Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

10 September 2017

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PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

10 September 2017

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Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

10 September 2017

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

10 September 2017

1 reference

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

10 September 2017

1 reference

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Deregulation of cyclin E in human cells interferes with prereplication complex assembly

10 September 2017

1 reference

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Replication protein A-mediated recruitment and activation of Rad17 complexes

10 September 2017

1 reference

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Cyclin-dependent kinases and S phase control in mammalian cells

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Chk1 and Chk2 kinases in checkpoint control and cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

E2F and cell cycle control: a double-edged sword

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

The RB and p53 pathways in cancer

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Essential role of human CDT1 in DNA replication and chromatin licensing

10 September 2017

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Analysis of Cdc6 function in the assembly of mammalian prereplication complexes

10 September 2017

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Cell cycle checkpoint signaling through the ATM and ATR kinases

10 September 2017

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The DNA replication checkpoint response stabilizes stalled replication forks

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Replication slippage involves DNA polymerase pausing and dissociation

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Activation of dormant origins of DNA replication in budding yeast

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Regulation of p53 stability by Mdm2

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Mdm2 promotes the rapid degradation of p53

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories.

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Increased global transcription activity as a mechanism of replication stress in cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Regulated eukaryotic DNA replication origin firing with purified proteins

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Yox1 links MBF-dependent transcription to completion of DNA synthesis

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Loss of DNA replication control is a potent inducer of gene amplification

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Tolerance of deregulated G1/S transcription depends on critical G1/S regulon genes to prevent catastrophic genome instability.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

The DNA damage and the DNA replication checkpoints converge at the MBF transcription factor

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

FANCD2 binds MCM proteins and controls replisome function upon activation of s phase checkpoint signaling.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

DNA replication stress differentially regulates G1/S genes via Rad53-dependent inactivation of Nrm1.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

G1/S transcription and the DNA synthesis checkpoint: common regulatory mechanisms.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

Does interference between replication and transcription contribute to genomic instability in cancer cells?

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

A central role for DNA replication forks in checkpoint activation and response

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5368696

21 August 2018

Identifiers

DOI

10.3390/GENES8030092

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28257104%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28257104%20AND%20SRC:MED&resulttype=core&format=json

4 April 2020

1 reference