Top-Down Mass Spectrometry: Proteomics to Proteoforms (Q39038792)

8 September 2017

Top-Down Mass Spectrometry: Proteomics to Proteoforms (English)

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8 September 2017

Steven M Patrie

1

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PubMed ID

27975217

8 September 2017

language of work or name

English

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publication date

1 January 2016

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Advances in Experimental Medicine and Biology

8 September 2017

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8 September 2017

919

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8 September 2017

171-200

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Proteoform: a single term describing protein complexity

8 September 2017

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

High throughput characterization of combinatorial histone codes

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Myelin proteomics: molecular anatomy of an insulating sheath

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Mass spectrometry-based proteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

100% protein sequence coverage: a modern form of surrealism in proteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

High-throughput middle-down analysis using an orbitrap

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Electrospray ionization for mass spectrometry of large biomolecules

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Protein and polymer analyses up tom/z 100 000 by laser ionization time-of-flight mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Micro-electrospray mass spectrometry: Ultra-high-sensitivity analysis of peptides and proteins.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Analytical characterization of the electrospray ion source in the nanoflow regime

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Practical implications of some recent studies in electrospray ionization fundamentals

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

MSSimulator: Simulation of mass spectrometry data.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Fourier transform ion cyclotron resonance mass spectrometry: a primer

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

The Orbitrap: a new mass spectrometer

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Unit mass baseline resolution for an intact 148 kDa therapeutic monoclonal antibody by Fourier transform ion cyclotron resonance mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Parts-per-billion mass measurement accuracy achieved through the combination of multiple linear regression and automatic gain control in a Fourier transform ion cyclotron resonance mass spectrometer

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Neutron-encoded mass signatures for quantitative top-down proteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Identification of Phosphorylated Human Peptides by Accurate Mass Measurement Alone

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Hybrid mass spectrometers for tandem mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Construction of a hybrid quadrupole/Fourier transform ion cyclotron resonance mass spectrometer for versatile MS/MS above 10 kDa.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Ultra high resolution linear ion trap Orbitrap mass spectrometer (Orbitrap Elite) facilitates top down LC MS/MS and versatile peptide fragmentation modes

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Mapping intact protein isoforms in discovery mode using top-down proteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Shotgun annotation of histone modifications: a new approach for streamlined characterization of proteins by top down mass spectrometry.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down protein characterization facilitated by ion/ion reactions on a quadrupole/time of flight platform.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down protein fragmentation by infrared multiphoton dissociation in a dual pressure linear ion trap

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Ion activation methods for tandem mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Collision-induced dissociation (CID) of peptides and proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Proposal for a common nomenclature for sequence ions in mass spectra of peptides

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Contributions of mass spectrometry to peptide and protein structure

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Higher-energy C-trap dissociation for peptide modification analysis.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Infrared multiphoton dissociation of large multiply charged ions for biomolecule sequencing

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Ultrafast ultraviolet photodissociation at 193 nm and its applicability to proteomic workflows.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

The utility of ETD mass spectrometry in proteomic analysis

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Combined electron capture and infrared multiphoton dissociation for multistage MS/MS in a Fourier transform ion cyclotron resonance mass spectrometer.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Glycoproteomics based on tandem mass spectrometry of glycopeptides

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Phosphopeptide fragmentation and analysis by mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Electron capture dissociation and infrared multiphoton dissociation MS/MS of an N-glycosylated tryptic peptic to yield complementary sequence information

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

On-line LC-MS approach combining collision-induced dissociation (CID), electron-transfer dissociation (ETD), and CID of an isolated charge-reduced species for the trace-level characterization of proteins with post-translational modifications

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Versatile online-offline engine for automated acquisition of high-resolution tandem mass spectra

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Automated de novo sequencing of proteins by tandem high-resolution mass spectrometry.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Deconvolution and database search of complex tandem mass spectra of intact proteins: a combinatorial approach

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Peptide sequence tags for fast database search in mass-spectrometry.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

De novo protein sequencing by combining top-down and bottom-up tandem mass spectra.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down tandem mass spectrometry on RNase A and B using a Qh/FT-ICR hybrid mass spectrometer

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

MASH Suite: a user-friendly and versatile software interface for high-resolution mass spectrometry data interpretation and visualization

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Informatics and multiplexing of intact protein identification in bacteria and the archaea

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Interpreting top-down mass spectra using spectral alignment.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Identification of ultramodified proteins using top-down tandem mass spectra.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Precursor ion independent algorithm for top-down shotgun proteomics.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Sensitive and specific identification of wild type and variant proteins from 8 to 669 kDa using top-down mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

On the scalability and requirements of whole protein mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Rapid separation and characterization of protein and peptide mixtures using 1.5 microns diameter non-porous silica in packed capillary liquid chromatography/mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down proteomics reveals a unique protein S-thiolation switch in Salmonella Typhimurium in response to infection-like conditions.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Analysis of bovine milk caseins on organic monolithic columns: an integrated capillary liquid chromatography-high resolution mass spectrometry approach for the study of time-dependent casein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down protein identification of proteasome proteins with nanoLC-FT-ICR-MS employing data-independent fragmentation methods

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Ultra-performance liquid chromatography/mass spectrometry of intact proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Efficient separations of intact proteins using slip-flow with nano-liquid chromatography-mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Ion-exchange chromatography for the characterization of biopharmaceuticals

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

"Proteotyping": population proteomics of human leukocytes using top down mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Integration of multidimensional chromatographic protein separations with a combined "top-down" and "bottom-up" proteomic strategy

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Automated proteomics of E. coli via top-down electron-transfer dissociation mass spectrometry.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Hydrophilic interaction liquid chromatography (HILIC)--a powerful separation technique

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Two-dimensional liquid chromatography system for online top-down mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Enhanced top-down characterization of histone post-translational modifications

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Capillary electrophoresis-mass spectrometry for the analysis of intact proteins 2007-2010.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Capillary electrophoresis-mass spectrometry for the analysis of intact proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Using size exclusion chromatography-RPLC and RPLC-CIEF as two-dimensional separation strategies for protein profiling

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Fast top-down intact protein characterization with capillary zone electrophoresis-electrospray ionization tandem mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Capillary zone electrophoresis-electrospray ionization-tandem mass spectrometry for top-down characterization of the Mycobacterium marinum secretome

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Optimizing capillary electrophoresis for top-down proteomics of 30-80 kDa proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

In-line separation by capillary electrophoresis prior to analysis by top-down mass spectrometry enables sensitive characterization of protein complexes

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Sequencing covalent modifications of membrane proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

A comparison of drug-treated and untreated HCT-116 human colon adenocarcinoma cells using a 2-D liquid separation mapping method based upon chromatofocusing PI fractionation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

IEF-based multidimensional applications in proteomics: toward higher resolution

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down mass spectrometry on tissue extracts and biofluids with isoelectric focusing and superficially porous silica liquid chromatography.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

State of the art of 2D DIGE.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Size-exclusion chromatography-from high-performance to ultra-performance

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Structure and dynamics of small soluble Aβ(1-40) oligomers studied by top-down hydrogen exchange mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Ultrahigh pressure fast size exclusion chromatography for top-down proteomics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Processing complex mixtures of intact proteins for direct analysis by mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Multiplexed size separation of intact proteins in solution phase for mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Size-based protein separations by microchip electrophoresis using an acid-labile surfactant as a replacement for SDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Tissue-specific expression and post-translational modification of histone H3 variants

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Precise characterization of human histones in the H2A gene family by top down mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

The first pilot project of the consortium for top-down proteomics: a status report

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Myelin basic protein undergoes a broader range of modifications in mammals than in lower vertebrates

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Detection of genetic variants of transthyretin by liquid chromatography-dual electrospray ionization fourier-transform ion-cyclotron-resonance mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-Down Analysis of Small Plasma Proteins Using an LTQ-Orbitrap. Potential for Mass Spectrometry-Based Clinical Assays for Transthyretin and Hemoglobin

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down proteomics of a drop of blood for diabetes monitoring

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down and bottom-up identification of proteins by liquid extraction surface analysis mass spectrometry of healthy and diseased human liver tissue.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Stepwise deamidation of ribonuclease A at five sites determined by top down mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down study of β2-microglobulin deamidation

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

A top-down LC-FTICR MS-based strategy for characterizing oxidized calmodulin in activated macrophages

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down quantitative proteomics identified phosphorylation of cardiac troponin I as a candidate biomarker for chronic heart failure

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Augmented phosphorylation of cardiac troponin I in hypertensive heart failure

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Proteolytic elimination of N-myristoyl modifications by the Shigella virulence factor IpaJ

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Motility and flagellar glycosylation in Clostridium difficile.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Flagellar glycosylation in Clostridium botulinum

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

The way forward, enhanced characterization of therapeutic antibody glycosylation: comparison of three level mass spectrometry-based strategies.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Tandem mass spectrometry of ribonuclease A and B: N-linked glycosylation site analysis of whole protein ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Quantitative analysis of intact apolipoproteins in human HDL by top-down differential mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

'Top down' protein characterization via tandem mass spectrometry

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Interlaboratory study on differential analysis of protein glycosylation by mass spectrometry: the ABRF glycoprotein research multi-institutional study 2012

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Analytical strategies for the global quantification of intact proteins

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Evaluation of intact mass spectrometry for the quantitative analysis of protein therapeutics

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Two dimensional liquid chromatography-ultraviolet/mass spectrometric (2DLC-UV/MS) analyses for quantitation of intact proteins in complex biological matrices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

An algorithm for identifying multiply modified endogenous proteins using both full-scan and high-resolution tandem mass spectrometric data

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Applying label-free quantitation to top down proteomics.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Quantitative analysis of modified proteins and their positional isomers by tandem mass spectrometry: human histone H4.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Direct comparison of stable isotope labeling by amino acids in cell culture and spectral counting for quantitative proteomics.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down quantitation and characterization of SILAC-labeled proteins.

21 January 2018

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https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Quantitative top-down proteomics of SILAC labeled human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Analytical techniques and bioactivity assays to compare the structure and function of filgrastim (granulocyte-colony stimulating factor) therapeutics from different manufacturers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Identification of site-specific heterogeneity in peptide drugs using intact mass spectrometry with electron transfer dissociation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

A platform for characterizing therapeutic monoclonal antibody breakdown products by 2D chromatography and top-down mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Top-down structural analysis of an intact monoclonal antibody by electron capture dissociation-Fourier transform ion cyclotron resonance-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Characterization of variable regions of monoclonal antibodies by top-down mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-41448-5_8

Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-Orbitrap mass spectrometer

21 January 2018

1 reference

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Analysis of reduced monoclonal antibodies using size exclusion chromatography coupled with mass spectrometry

21 January 2018

1 reference

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Structural analysis of an intact monoclonal antibody by online electrochemical reduction of disulfide bonds and Fourier transform ion cyclotron resonance mass spectrometry.

21 January 2018

1 reference

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Profiling of integral membrane proteins and their post translational modifications using high-resolution mass spectrometry

21 January 2018

1 reference

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Top-down mass spectrometry of integral membrane proteins

21 January 2018

1 reference

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Analysis of hydrophobic proteins and peptides by electrospray ionization mass spectrometry.

21 January 2018

1 reference

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Full subunit coverage liquid chromatography electrospray ionization mass spectrometry (LCMS+) of an oligomeric membrane protein: cytochrome b(6)f complex from spinach and the cyanobacterium Mastigocladus laminosus

21 January 2018

1 reference

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Identification of membrane proteins by tandem mass spectrometry of protein ions

21 January 2018

1 reference

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Resolubilization of precipitated intact membrane proteins with cold formic acid for analysis by mass spectrometry.

21 January 2018

1 reference

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Data-directed top-down Fourier-transform mass spectrometry of a large integral membrane protein complex: photosystem II from Galdieria sulphuraria.

21 January 2018

1 reference

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Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation

21 January 2018

1 reference

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Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence.

21 January 2018

1 reference

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Top down proteomics of human membrane proteins from enriched mitochondrial fractions

21 January 2018

1 reference

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Increased coverage in the transmembrane domain with activated-ion electron capture dissociation for top-down Fourier-transform mass spectrometry of integral membrane proteins

21 January 2018

1 reference

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H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach?

21 January 2018

1 reference

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Protein conformations can be probed in top-down HDX MS experiments utilizing electron transfer dissociation of protein ions without hydrogen scrambling.

21 January 2018

1 reference

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Electron capture dissociation of electrosprayed protein ions for spatially resolved hydrogen exchange measurements

21 January 2018

1 reference

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Approach to characterization of the higher order structure of disulfide-containing proteins using hydrogen/deuterium exchange and top-down mass spectrometry

21 January 2018

1 reference

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Spatially resolved protein hydrogen exchange measured by subzero-cooled chip-based nanoelectrospray ionization tandem mass spectrometry.

21 January 2018

1 reference

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Subzero temperature chromatography and top-down mass spectrometry for protein higher-order structure characterization: method validation and application to therapeutic antibodies

21 January 2018

1 reference

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New reagents for increasing ESI multiple charging of proteins and protein complexes

21 January 2018

1 reference

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Dissecting the large noncovalent protein complex GroEL with surface-induced dissociation and ion mobility-mass spectrometry

21 January 2018

1 reference

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Studying 18 MDa virus assemblies with native mass spectrometry

21 January 2018

1 reference

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Revealing the quaternary structure of a heterogeneous noncovalent protein complex through surface-induced dissociation

21 January 2018

1 reference

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From protein complexes to subunit backbone fragments: a multi-stage approach to native mass spectrometry.

21 January 2018

1 reference

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Evaluation of the compact high-field orbitrap for top-down proteomics of human cells

21 January 2018

1 reference

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Performance evaluation of a high-field Orbitrap mass analyzer

21 January 2018

1 reference

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Fourier transform mass spectrometry

21 January 2018

1 reference

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Automated broadband phase correction of Fourier transform ion cyclotron resonance mass spectra

21 January 2018

1 reference

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Tandem Native Mass-Spectrometry on Antibody-Drug Conjugates and Submillion Da Antibody-Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector

21 January 2018

1 reference

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Elucidating the site of protein-ATP binding by top-down mass spectrometry

21 January 2018

1 reference

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Native electrospray and electron-capture dissociation in FTICR mass spectrometry provide top-down sequencing of a protein component in an intact protein assembly.

21 January 2018

1 reference

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Revealing ligand binding sites and quantifying subunit variants of noncovalent protein complexes in a single native top-down FTICR MS experiment

21 January 2018

1 reference

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Native GELFrEE: a new separation technique for biomolecular assemblies

21 January 2018

1 reference

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Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology

21 January 2018

1 reference

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Nanoflow LC/IMS-MS and LC/IMS-CID/MS of protein mixtures

21 January 2018

1 reference

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Ion mobility-mass spectrometry (IM-MS) for top-down proteomics: increased dynamic range affords increased sequence coverage

21 January 2018

1 reference

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Structural stability from solution to the gas phase: native solution structure of ubiquitin survives analysis in a solvent-free ion mobility-mass spectrometry environment

21 January 2018

1 reference

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Conformation types of ubiquitin [M+8H]8+ Ions from water:methanol solutions: evidence for the N and A States in aqueous solution

21 January 2018

1 reference

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Selected overtone mobility spectrometry

21 January 2018

1 reference

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Ion mobility separation of variant histone tails extending to the "middle-down" range

21 January 2018

1 reference

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Electron-capture dissociation and ion mobility mass spectrometry for characterization of the hemoglobin protein assembly

21 January 2018

1 reference

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Interactions between amyloid-β and Tau fragments promote aberrant aggregates: implications for amyloid toxicity

21 January 2018

1 reference

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Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry

21 January 2018

1 reference

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A mass-spectrometry-based framework to define the extent of disorder in proteins

21 January 2018

1 reference

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Chemical noise reduction via mass spectrometry and ion/ion charge inversion: amino acids

21 January 2018

1 reference

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Recent developments in the ion/ion chemistry of high-mass multiply charged ions

21 January 2018

1 reference

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Peptide and protein ion/ion reactions in electrodynamic ion traps: tools and methods.

21 January 2018

1 reference

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Simultaneous transmission mode collision-induced dissociation and ion/ion reactions for top-down protein identification/characterization using a quadrupole/time-of-flight tandem mass spectrometer

21 January 2018

1 reference

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Controlling gas-phase reactions for efficient charge reduction electrospray mass spectrometry of intact proteins

21 January 2018

1 reference

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Charge reduction electrospray mass spectrometry

21 January 2018

1 reference

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Analysis of intact proteins on a chromatographic time scale by electron transfer dissociation tandem mass spectrometry

21 January 2018

1 reference

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Solution additives for supercharging proteins beyond the theoretical maximum proton-transfer limit in electrospray ionization mass spectrometry

21 January 2018

1 reference

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Surfactant effects on protein structure examined by electrospray ionization mass spectrometry

21 January 2018

1 reference

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Supercharged protein and peptide ions formed by electrospray ionization

21 January 2018

1 reference

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New reagents for enhanced liquid chromatographic separation and charging of intact protein ions for electrospray ionization mass spectrometry

21 January 2018

1 reference

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Effects of solvent on the maximum charge state and charge state distribution of protein ions produced by electrospray ionization

21 January 2018

1 reference

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Anions in electrothermal supercharging of proteins with electrospray ionization follow a reverse Hofmeister series

21 January 2018

1 reference

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Electrothermal supercharging of proteins in native electrospray ionization

21 January 2018

1 reference

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The ABRF Proteomics Research Group Studies: Educational exercises for qualitative and quantitative proteomic analyses

21 January 2018

1 reference

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Utility of Accurate Mass Tags for Proteome-Wide Protein Identification

21 January 2018

1 reference

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Proteomic Profiling of Intact Proteins Using WAX-RPLC 2-D Separations and FTICR Mass Spectrometry

21 January 2018

1 reference

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Proteome analysis using selective incorporation of isotopically labeled amino acids

21 January 2018

1 reference

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Attomole-sensitivity electrospray source for large-molecule mass spectrometry

21 January 2018

1 reference

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Sensitive and reproducible intact mass analysis of complex protein mixtures with superficially porous capillary reversed-phase liquid chromatography mass spectrometry

31 March 2020

1 reference

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Microspray and microflow LC-MS/MS: the perfect fit for bioanalysis

31 March 2020

1 reference

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Top down mass spectrometry of < 60-kDa proteins from Methanosarcina acetivorans using quadrupole FRMS with automated octopole collisionally activated dissociation

31 March 2020

1 reference

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An accurate mass tag strategy for quantitative and high-throughput proteome measurements

31 March 2020

1 reference

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Electrospray ionization Fourier transform ion cyclotron resonance at 9.4 T

31 March 2020

1 reference

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Pervasive combinatorial modification of histone H3 in human cells

31 March 2020

1 reference

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Generating protein sequence tags by combining cone and conventional collision induced dissociation in a quadrupole time-of-flight mass spectrometer

31 March 2020

1 reference

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Tandem mass spectrometry of peptides using hybrid and four-sector instruments: A comparative study

31 March 2020

1 reference

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Electron transfer dissociation of N-glycopeptides: loss of the entire N-glycosylated asparagine side chain

31 March 2020

1 reference

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Charge state dependent top-down characterisation using electron transfer dissociation

31 March 2020

1 reference

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ProSight Lite: graphical software to analyze top-down mass spectrometry data

31 March 2020

1 reference

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High-resolution separations of protein isoforms with liquid chromatography time-of-flight mass spectrometry using polymer monolithic capillary columns

31 March 2020

1 reference

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Low-flow sheathless capillary electrophoresis-mass spectrometry for sensitive glycoform profiling of intact pharmaceutical proteins

31 March 2020

1 reference

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Proteoform analysis of lipocalin-type prostaglandin D-synthase from human cerebrospinal fluid by isoelectric focusing and superficially porous liquid chromatography with Fourier transform mass spectrometry

31 March 2020

1 reference

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Mass spectrometric detection for capillary isoelectric focusing separations of complex protein mixtures

31 March 2020

1 reference

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A new approach for plant proteomics: characterization of chloroplast proteins of Arabidopsis thaliana by top-down mass spectrometry

31 March 2020

1 reference

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Top-Down Proteomics and Direct Surface Sampling of Neonatal Dried Blood Spots: Diagnosis of Unknown Hemoglobin Variants

31 March 2020

1 reference

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Mass spectrometric characterization of human histone H3: a bird's eye view

31 March 2020

1 reference

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Top-down N-terminal sequencing of Immunoglobulin subunits with electrospray ionization time of flight mass spectrometry

31 March 2020

1 reference

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Top-down mass spectrometry and hydrogen/deuterium exchange for comprehensive structural characterization of interferons: implications for biosimilars

31 March 2020

1 reference

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Native mass spectrometry as a tool in structural biology

31 March 2020

1 reference

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Broadband phase correction of FT-ICR mass spectra via simultaneous excitation and detection

31 March 2020

1 reference

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High-performance mass spectrometry: Fourier transform ion cyclotron resonance at 14.5 Tesla

31 March 2020

1 reference

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Ultrahigh-resolution differential ion mobility separations of conformers for proteins above 10 kDa: onset of dipole alignment?

31 March 2020

1 reference

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Charge determination of product ions formed from collision-induced dissociation of multiply protonated molecules via ion/molecule reactions

31 March 2020

1 reference

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Electrospray ionization mass spectrometry of highly heterogeneous protein systems: protein ion charge state assignment via incomplete charge reduction

31 March 2020

1 reference

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Ion Parking during Ion/Ion Reactions in Electrodynamic Ion Traps

31 March 2020

1 reference

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10.1007/978-3-319-41448-5_8

31 March 2020

Identifiers

DOI

0 references

PubMed ID

27975217

1 reference

PubMed ID

27975217