A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation (Q38834978)

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scientific article published on 16 September 2015

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English	A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation	scientific article published on 16 September 2015

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scholarly article

1 reference

Europe PubMed Central

6 September 2017

A phosphomimetic mutant of RelA/p65 at Ser536 induces apoptosis and senescence: An implication for tumor-suppressive role of Ser536 phosphorylation (English)

1 reference

Europe PubMed Central

6 September 2017

author name string

Yiwen Bu

1

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Europe PubMed Central

6 September 2017

Xiaoning Li

2

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Europe PubMed Central

6 September 2017

Yingchun He

3

1 reference

Europe PubMed Central

6 September 2017

Chenfei Huang

4

1 reference

Europe PubMed Central

6 September 2017

Yi Shen

5

1 reference

Europe PubMed Central

6 September 2017

Yu Cao

6

1 reference

Europe PubMed Central

6 September 2017

Dan Huang

7

1 reference

Europe PubMed Central

6 September 2017

Chuan Cai

8

1 reference

Europe PubMed Central

6 September 2017

Yuhong Wang

9

1 reference

Europe PubMed Central

6 September 2017

Ziqi Wang

10

1 reference

Europe PubMed Central

6 September 2017

Duan-Fang Liao

11

1 reference

Europe PubMed Central

6 September 2017

Deliang Cao

12

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Europe PubMed Central

6 September 2017

language of work or name

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publication date

16 September 2015

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Europe PubMed Central

6 September 2017

number of pages

13

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International Journal of Cancer

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6 September 2017

138

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6 September 2017

5

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Europe PubMed Central

6 September 2017

1186-1198

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Europe PubMed Central

6 September 2017

Signaling to NF-kappaB

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The nuclear factor NF-kappaB pathway in inflammation

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Shared principles in NF-kappaB signaling

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Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathway

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21 January 2018

Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B.

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21 January 2018

Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

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21 January 2018

Site-specific phosphorylation of the p65 protein subunit mediates selective gene expression by differential NF-κB and RNA polymerase II promoter recruitment

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21 January 2018

IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation

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21 January 2018

Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding [...]

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21 January 2018

IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.

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21 January 2018

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

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The Two Faces of NF-κB Signaling in Cancer Development and Therapy.

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A loss-of-function RNA interference screen for molecular targets in cancer

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Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis

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Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells.

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21 January 2018

NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis

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21 January 2018

Mitogenic and antiapoptotic role of constitutive NF-kappaB/Rel activity in pancreatic cancer.

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21 January 2018

Targeting NF-kappaB for colorectal cancer

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Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

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21 January 2018

NF-kappaB signaling pathway, inflammation and colorectal cancer.

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21 January 2018

Oncogenic activation of NF-kappaB.

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21 January 2018

Methylated chrysin induces co-ordinated attenuation of the canonical Wnt and NF-kB signaling pathway and upregulates apoptotic gene expression in the early hepatocarcinogenesis rat model

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21 January 2018

Inhibitors of NF-kappaB signaling: 785 and counting

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21 January 2018

To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis

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21 January 2018

relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells.

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21 January 2018

PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis

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21 January 2018

Role of NF-κB in p53-mediated programmed cell death

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21 January 2018

NF-kappaB and IKK as therapeutic targets in cancer

1 reference

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21 January 2018

Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway

1 reference

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21 January 2018

Heat shock protein 90-α mediates aldo-keto reductase 1B10 (AKR1B10) protein secretion through secretory lysosomes

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21 January 2018

Epidermal growth factor induces tumour marker AKR1B10 expression through activator protein-1 signalling in hepatocellular carcinoma cells

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21 January 2018

Aldo-keto reductase family 1 member B10 promotes cell survival by regulating lipid synthesis and eliminating carbonyls

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21 January 2018

Aldo-keto reductase family 1, member B10 is secreted through a lysosome-mediated non-classical pathway

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21 January 2018

Changes in apoptosis during the development of colorectal cancer: a systematic review of the literature

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21 January 2018

Metalloproteinase-mediated release of human Fas ligand

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21 January 2018

The essence of senescence

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21 January 2018

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

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21 January 2018

Immortalization of human mammary epithelial cells is associated with inactivation of the p14ARF-p53 pathway

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21 January 2018

The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration

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21 January 2018

Nuclear NF-kappaB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer.

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21 January 2018

Constitutive NF-kappaB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth

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21 January 2018

NF-κB p65 phosphorylated at serine-536 is an independent prognostic factor in Swedish colorectal cancer patients.

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NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells

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Suppression of PTEN expression by NF-kappa B prevents apoptosis

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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AKR1B10 overexpression in breast cancer: association with tumor size, lymph node metastasis and patient survival and its potential as a novel serum marker

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21 January 2018

Identifiers

10.1002/IJC.29852

1 reference

Europe PubMed Central

6 September 2017

1 reference

Europe PubMed Central

6 September 2017

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