Kv10.1 K(+) channel: from physiology to cancer. (Q38690062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26743871%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Kv10.1 K(+) channel: from physiology to cancer (English)

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4 March 2020

3

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4 March 2020

author name string

Halima Ouadid-Ahidouch

series ordinal

1

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4 March 2020

Ahmed Ahidouch

series ordinal

2

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4 March 2020

publication date

8 January 2016

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4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26743871%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

468

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4 March 2020

issue

5

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4 March 2020

page(s)

751-762

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https://scigraph.springernature.com/pub.10.1007/s00424-015-1784-3

4 March 2020

exact match

0 references

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21 January 2018

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Oncogenic potential of EAG K(+) channels

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An ether -à-go-go K+ current, Ih-eag, contributes to the hyperpolarization of human fusion-competent myoblasts.

21 January 2018

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Ether à go-go potassium channel expression in soft tissue sarcoma patients

21 January 2018

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Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.

21 January 2018

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Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP.

21 January 2018

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Sh and eag K(+) channel subunit interaction in frog oocytes depends on level and time of expression

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Shaker and ether-à-go-go K+ channel subunits fail to coassemble in Xenopus oocytes

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Carboxy-terminal domain mediates assembly of the voltage-gated rat ether-à-go-go potassium channel

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Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes

21 January 2018

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Subunit folding and assembly steps are interspersed during Shaker potassium channel biogenesis

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Heteromeric assembly of human ether-à-go-go-related gene (hERG) 1a/1b channels occurs cotranslationally via N-terminal interactions

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Distal end of carboxyl terminus is not essential for the assembly of rat Eag1 potassium channels

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C-terminal domains implicated in the functional surface expression of potassium channels

21 January 2018

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The subfamily-specific assembly of Eag and Erg K+ channels is determined by both the amino and the carboxyl recognition domains

21 January 2018

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Influence of C-terminal protein domains and protein-lipid interactions on tetramerization and stability of the potassium channel KcsA.

21 January 2018

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Glycosylation of Eag1 (Kv10.1) potassium channels: intracellular trafficking and functional consequences

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Potassium ion current in the squid giant axon: dynamic characteristic

21 January 2018

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Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment

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Extracellular Mg2+ regulates activation of rat eag potassium channel.

21 January 2018

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Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.

21 January 2018

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Structural properties of PAS domains from the KCNH potassium channels

21 January 2018

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21 January 2018

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Influence of amino-terminal structures on kinetic transitions between several closed and open states in human erg K+ channels.

21 January 2018

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Molecular regions responsible for differences in activation between heag channels.

21 January 2018

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Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain

21 January 2018

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Structural basis of two-stage voltage-dependent activation in K+ channels

21 January 2018

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21 January 2018

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Absence of direct cyclic nucleotide modulation of mEAG1 and hERG1 channels revealed with fluorescence and electrophysiological methods

21 January 2018

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Functional K(v)10.1 channels localize to the inner nuclear membrane

21 January 2018

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Elevation of intracellular calcium by muscarinic receptor activation induces a block of voltage-activated rat ether-à-go-go channels in a stably transfected cell line

21 January 2018

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Calmodulin interaction with hEAG1 visualized by FRET microscopy

21 January 2018

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21 January 2018

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21 January 2018

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Current inhibition of human EAG1 potassium channels by the Ca2+ binding protein S100B

21 January 2018

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Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel

21 January 2018

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21 January 2018

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21 January 2018

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Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes

21 January 2018

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21 January 2018

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KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels

21 January 2018

1 reference

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14-3-3θ is a binding partner of rat Eag1 potassium channels

21 January 2018

1 reference

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PIST (GOPC) modulates the oncogenic voltage-gated potassium channel KV10.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Cytoskeletal interactions determine the electrophysiological properties of human EAG potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Interaction of the K channel beta subunit, Hyperkinetic, with eag family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The eag potassium channel binds and locally activates calcium/calmodulin-dependent protein kinase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Rapid internalization of the oncogenic K+ channel K(V)10.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Involvement of genes encoding a K+ channel (ether a go-go) and a Na+ channel (smellblind) in Drosophila olfaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Differential localization of rat Eag1 and Eag2 K+ channels in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Differential localization of rat Eag1 and Eag2 potassium channels in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Temporal mismatch between pain behaviour, skin Nerve Growth factor and intra-epidermal nerve fibre density in trigeminal neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

KV 10.1 opposes activity-dependent increase in Ca2+ influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Eag1 and Bestrophin 1 are up-regulated in fast-growing colonic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The roles of K(+) channels in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Regulation of IGF-1-dependent cyclin D1 and E expression by hEag1 channels in MCF-7 cells: the critical role of hEag1 channels in G1 phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Eag1 expression interferes with hypoxia homeostasis and induces angiogenesis in tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Astemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

K+ channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Potassium channels in cell cycle and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

DNA methylation of channel-related genes in cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Large-scale characterization of DNA methylation changes in human gastric carcinomas with and without metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

DNA methylation in tumor and matched normal tissues from non-small cell lung cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Transcriptional and post-transcriptional mechanisms for oncogenic overexpression of ether à go-go K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Antitumor mechanisms when pRb and p53 are genetically inactivated

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

MiR-296-3p regulates cell growth and multi-drug resistance of human glioblastoma by targeting ether-à-go-go (EAG1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Papillomaviruses and cancer: from basic studies to clinical application

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Potassium channels keep mobile cells on the go.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Human ether à-gogo K(+) channel 1 (hEag1) regulates MDA-MB-231 breast cancer cell migration through Orai1-dependent calcium entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Calcitriol inhibits Ether-à go-go potassium channel expression and cell proliferation in human breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

A novel native store-operated calcium channel encoded by Orai3: selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Orai1 and STIM1 are critical for breast tumor cell migration and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

21 January 2018

S100 proteins in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Pivotal role of the lipid Raft SK3-Orai1 complex in human cancer cell migration and bone metastases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Identification of SK3 channel as a new mediator of breast cancer cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Physical and functional interaction between integrins and hERG potassium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Human ether-a-go-go-related gene 1 channels are physically linked to beta1 integrins and modulate adhesion-dependent signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

HERG K+ channels and beta1 integrins interact through the assembly of a macromolecular complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Putting tumours in context

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Acid-base transport in pancreatic cancer: molecular mechanisms and clinical potential.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The chemistry, physiology and pathology of pH in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The impact of O2 availability on human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Biological consequences of tumor hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Structural, biochemical, and functional characterization of the cyclic nucleotide binding homology domain from the mouse EAG1 potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Hypoxia-inducible factor 1 (HIF-1) pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Tumor hypoxia and malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Positive correlation between the expression of hEag1 and HIF-1α in breast cancers: an observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Integrins in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Effect of extracellular matrix on adhesion, viability, actin cytoskeleton and K+ currents of cells expressing human ether à go-go channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The Eag potassium channel as a new prognostic marker in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Short Hairpin RNA (shRNA) Ether à go-go 1 (Eag1) inhibition of human osteosarcoma angiogenesis via VEGF/PI3K/AKT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

The Y-box binding protein YB-1 is associated with progressive disease and mediates survival and drug resistance in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Expression of ether à go-go potassium channels in human gliomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Silencing of Ether à go-go 1 by shRNA inhibits osteosarcoma growth and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Potassium channel ether à go-go1 is aberrantly expressed in human liposarcoma and promotes tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Ether a go-go potassium channels as human cervical cancer markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Aberrant expression of ether à go-go potassium channel in colorectal cancer patients and cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

SIGNAL TRANSDUCTION. Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Analysis of the expression of Kv10.1 potassium channel in patients with brain metastases and glioblastoma multiforme: impact on survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Monoclonal Antibody Blockade of the Human Eag1 Potassium Channel Function Exerts Antitumor Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Different relevance of inactivation and F468 residue in the mechanisms of hEag1 channel blockage by astemizole, imipramine and dofetilide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Expression of Voltage-Gated Potassium Channels in Human and Mouse Colonic Carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-015-1784-3

Identification of ether à go-go and calcium-activated potassium channels in human melanoma cells

21 January 2018

1 reference

12 December 2020

Cloning of components of a novel subthreshold-activating K(+) channel with a unique pattern of expression in the cerebral cortex.

1 reference

12 December 2020

p38 MAPK regulates the expression of ether à go-go potassium channel in human osteosarcoma cells

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12 December 2020

Potassium channel ether à go-go mRNA expression in the spiral ligament of the rat

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12 December 2020

Integrins and ion channels in cell migration: implications for neuronal development, wound healing and metastatic spread

1 reference

12 December 2020

Expression of Eag1 K+ channel and ErbBs in human pituitary adenomas: cytoskeleton arrangement patterns in cultured cells

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12 December 2020

The behavior of four neurological mutants of Drosophila

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12 December 2020

Relationship of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression to vascular endothelial growth factor induction and hypoxia survival in human breast cancer cell lines.

1 reference

12 December 2020

Individual subunits contribute independently to slow gating of bovine EAG potassium channels

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12 December 2020

RNA interference with EAG1 enhances interferon gamma injury to glioma cells in vitro.

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12 December 2020

Expression and prognostic roles of Eag1 in resected esophageal squamous cell carcinomas

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12 December 2020

Human EAG1 potassium channels in the epithelial-to-mesenchymal transition in lung cancer cells.

1 reference

12 December 2020

Mutations in KCNH1 and ATP6V1B2 cause Zimmermann-Laband syndrome.

1 reference

12 December 2020

Differential expression of genes encoding subthreshold-operating voltage-gated K+ channels in brain.

1 reference

12 December 2020

Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart

1 reference

12 December 2020

Changes in the K+ current-density of MCF-7 cells during progression through the cell cycle: possible involvement of a h-ether.a-gogo K+ channel.

1 reference

12 December 2020

Modulation of different K+ currents in Drosophila: a hypothetical role for the Eag subunit in multimeric K+ channels.

1 reference

12 December 2020

The punctate localization of rat Eag1 K+ channels is conferred by the proximal post-CNBHD region

1 reference

12 December 2020

A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.

1 reference

12 December 2020