The multifaceted roles of intrinsic disorder in protein complexes (Q38527462)

3 September 2017

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title

The multifaceted roles of intrinsic disorder in protein complexes (English)

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3 September 2017

1

Vladimir N Uversky

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PubMed ID

26073257

3 September 2017

language of work or name

English

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publication date

11 June 2015

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3 September 2017

9

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based on heuristic

inferred from page(s)

published in

FEBS Letters

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3 September 2017

589

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3 September 2017

19 Pt A

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3 September 2017

2498-2506

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Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life

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1 reference

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The mysterious unfoldome: structureless, underappreciated, yet vital part of any given proteome

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1 reference

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The relationship between proteome size, structural disorder and organism complexity

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Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life

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1 reference

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Intrinsically unstructured proteins and their functions

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Coupling of folding and binding for unstructured proteins

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Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

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Function and structure of inherently disordered proteins

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Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

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Showing your ID: intrinsic disorder as an ID for recognition, regulation and cell signaling

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Intrinsic disorder and protein function

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Intrinsically disordered protein

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The unfoldomics decade: an update on intrinsically disordered proteins.

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Signal transduction via unstructured protein conduits.

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Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes

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Intrinsic disorder-based protein interactions and their modulators

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Intrinsic disorder is a common feature of hub proteins from four eukaryotic interactomes

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Unusual biophysics of intrinsically disordered proteins

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The protein trinity--linking function and disorder.

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Natively unfolded proteins: a point where biology waits for physics

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What does it mean to be natively unfolded?

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The interplay between structure and function in intrinsically unstructured proteins.

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Folding and assembly of oligomeric proteins in Escherichia coli

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Mechanism and evolution of protein dimerization

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Analysis of ordered and disordered protein complexes reveals structural features discriminating between stable and unstable monomers.

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Disordered proteinaceous machines

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A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome

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More than just tails: intrinsic disorder in histone proteins.

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Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

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Induced alpha helix in the VP16 activation domain upon binding to a human TAF

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Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions

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Mechanism of coupled folding and binding of an intrinsically disordered protein

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The physics and bioinformatics of binding and folding-an energy landscape perspective

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Structural flexibility of intrinsically disordered proteins induces stepwise target recognition.

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Intrinsic protein-protein interaction-mediated and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome

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Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits

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Dissecting beta-ring assembly pathway of the mammalian 20S proteasome.

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Assembly of Saccharomyces cerevisiae 60S ribosomal subunits: role of factors required for 27S pre-rRNA processing

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Protein complexes are under evolutionary selection to assemble via ordered pathways

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Parallel dynamics and evolution: Protein conformational fluctuations and assembly reflect evolutionary changes in sequence and structure.

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The role of salt bridges, charge density, and subunit flexibility in determining disassembly routes of protein complexes.

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Assembly reflects evolution of protein complexes

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Structural basis for regulation of protein phosphatase 1 by inhibitor-2

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Calcium-induced tripartite binding of intrinsically disordered calpastatin to its cognate enzyme, calpain

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Role of intrinsic flexibility in signal transduction mediated by the cell cycle regulator, p27 Kip1.

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Regulation of cell division by intrinsically unstructured proteins: intrinsic flexibility, modularity, and signaling conduits

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Crystal structure of a beta-catenin/Tcf complex

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An overview of the structures of protein-DNA complexes

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Molecular biology of HMGA proteins: hubs of nuclear function

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The solution structure of an HMG-I(Y)-DNA complex defines a new architectural minor groove binding motif

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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

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Structure of the 30S ribosomal subunit

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Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA

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Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface

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Self-assembly of biological macromolecules

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Polybivalency and disordered proteins in ordering macromolecular assemblies

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Designing a polyvalent inhibitor of anthrax toxin

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Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

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Flexible nets. The roles of intrinsic disorder in protein interaction networks.

21 January 2018

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Functional classification of scaffold proteins and related molecules

21 January 2018

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Intrinsic disorder in scaffold proteins: getting more from less

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High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1

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Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

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p27 binds cyclin-CDK complexes through a sequential mechanism involving binding-induced protein folding

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Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division

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Coupled folding and binding with alpha-helix-forming molecular recognition elements.

21 January 2018

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Mining alpha-helix-forming molecular recognition features with cross species sequence alignments

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Characterization of molecular recognition features, MoRFs, and their binding partners

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Understanding protein non-folding.

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Fuzzy complexes: polymorphism and structural disorder in protein-protein interactions

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Limitations of induced folding in molecular recognition by intrinsically disordered proteins

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Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif

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Binding of intrinsically disordered proteins is not necessarily accompanied by a structural transition to a folded form

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Conditionally and transiently disordered proteins: awakening cryptic disorder to regulate protein function

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Conditional disorder in chaperone action

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Stochastic machines as a colocalization mechanism for scaffold protein function

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Casein kinase I and casein kinase II differentially regulate axin function in Wnt and JNK pathways

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Crystal Structure of a Full-Length β-Catenin

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Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

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High mobility of proteins in the mammalian cell nucleus

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Review: properties and assembly mechanisms of ND10, PML bodies, or PODs

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Review: perinucleolar structures

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Nuclear speckles: a model for nuclear organelles

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Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition

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Edc3p and a glutamine/asparagine-rich domain of Lsm4p function in processing body assembly in Saccharomyces cerevisiae

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Germline P granules are liquid droplets that localize by controlled dissolution/condensation.

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Ultrastructural characterization of spermatogenesis and its evolutionary conservation in the germline: germinal granules in mammals

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Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis

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Limiting amounts of centrosome material set centrosome size in C. elegans embryos

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Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling

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Phase transitions and size scaling of membrane-less organelles

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Aqueous phase separation as a possible route to compartmentalization of biological molecules

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Phase transition of a disordered nuage protein generates environmentally responsive membraneless organelles

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SNAREpins: minimal machinery for membrane fusion

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Membrane fusion: grappling with SNARE and SM proteins

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Single-molecule studies of SNARE complex assembly reveal parallel and antiparallel configurations

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SNAP receptors implicated in vesicle targeting and fusion

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Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy

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Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

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DNA damage: RNA-binding proteins protect from near and far.

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The structure of the eukaryotic ribosome at 3.0 Å resolution

21 January 2018

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Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain

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Intrinsically disordered proteins as crucial constituents of cellular aqueous two phase systems and coacervates

21 January 2018

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10.1016/J.FEBSLET.2015.06.004

21 January 2018

Identifiers

DOI

1 reference

3 September 2017

1 reference

PubMed ID

26073257