Membrane fusion: grappling with SNARE and SM proteins (Q24633113)

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Europe PubMed Central

title

Membrane fusion: grappling with SNARE and SM proteins (English)

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1

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author name string

James E Rothman

series ordinal

2

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language of work or name

English

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publication date

23 January 2009

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published in

Science

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volume

323

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page(s)

474-7

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issue

5913

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ScienceSource

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cites work

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7 April 2017

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Topological restriction of SNARE-dependent membrane fusion

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Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily

7 April 2017

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SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex

7 April 2017

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SNAP receptors implicated in vesicle targeting and fusion

7 April 2017

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SNAREpins: minimal machinery for membrane fusion

7 April 2017

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A complexin/synaptotagmin 1 switch controls fast synaptic vesicle exocytosis

7 April 2017

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Synaptotagmin I functions as a calcium regulator of release probability

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Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex

7 April 2017

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A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding

7 April 2017

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A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

7 April 2017

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SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

7 April 2017

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7 April 2017

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Sly1 binds to Golgi and ER syntaxins via a conserved N-terminal peptide motif

7 April 2017

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Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy

7 April 2017

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Sec18p (NSF)-driven release of Sec17p (alpha-SNAP) can precede docking and fusion of yeast vacuoles

7 April 2017

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Identification of the nerve terminal targets of botulinum neurotoxin serotypes A, D, and E

7 April 2017

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7 April 2017

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Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin

7 April 2017

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Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

7 April 2017

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Tetanus toxin action: inhibition of neurotransmitter release linked to synaptobrevin proteolysis

7 April 2017

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Purification of active HOPS complex reveals its affinities for phosphoinositides and the SNARE Vam7p

7 April 2017

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Crossref

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Alternative zippering as an on-off switch for SNARE-mediated fusion

22 April 2017

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Synaptic assembly of the brain in the absence of neurotransmitter secretion

22 April 2017

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Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

7 April 2017

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Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

7 April 2017

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7 April 2017

Synaptic vesicle fusion

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SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes

27 September 2017

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An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system

27 September 2017

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Multiple intermediates in SNARE-induced membrane fusion

27 September 2017

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A clamping mechanism involved in SNARE-dependent exocytosis

27 September 2017

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Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release

27 September 2017

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The energetics of membrane fusion from binding, through hemifusion, pore formation, and pore enlargement

27 September 2017

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Single molecule observation of liposome-bilayer fusion thermally induced by soluble N-ethyl maleimide sensitive-factor attachment protein receptors (SNAREs)

27 September 2017

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Three SNARE complexes cooperate to mediate membrane fusion

27 September 2017

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Complexins regulate a late step in Ca2+-dependent neurotransmitter release

27 September 2017

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Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors

27 September 2017

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Timing of neurotransmission at fast synapses in the mammalian brain

27 September 2017

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VAMP-1: a synaptic vesicle-associated integral membrane protein

27 September 2017

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The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations

27 September 2017

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A synaptic vesicle membrane protein is conserved from mammals to Drosophila

27 September 2017

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The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast

27 September 2017

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Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1

27 September 2017

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Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

27 September 2017

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Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Synaptotagmin: a calcium sensor on the synaptic vesicle surface.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Distinct targeting and fusion functions of the PX and SNARE domains of yeast vacuolar Vam7p.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

A gain-of-function mutation in synaptotagmin-1 reveals a critical role of Ca2+-dependent soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex binding in synaptic exocytosis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Hemifusion arrest by complexin is relieved by Ca2+-synaptotagmin I.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Structural determinants of synaptobrevin 2 function in synaptic vesicle fusion.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Ca2+ regulates the interaction between synaptotagmin and syntaxin 1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3736821

Functional architecture of an intracellular membrane t-SNARE

28 November 2018

1 reference

12 December 2020

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

1 reference

12 December 2020

The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion

1 reference

12 December 2020

Energetics and dynamics of SNAREpin folding across lipid bilayers

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1161748

1 reference

471306

471306

1 reference

1 reference

1 reference