Roles of divalent metal ions in flap endonuclease-substrate interactions. (Q38342596)

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27 December 2019

title

Roles of divalent metal ions in flap endonuclease-substrate interactions (English)

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7

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author name string

Min Feng

1

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Dipak Patel

2

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Joe J Dervan

3

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Thomas Ceska

4

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Dietrich Suck

5

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Ihtshamul Haq

6

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publication date

11 April 2004

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Nature Structural & Molecular Biology

27 December 2019

language of work or name

English

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published in

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volume

11

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issue

5

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page(s)

450-456

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The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

27 December 2019

cites work

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Structure-specific DNA cleavage by 5' nucleases

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Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

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Streptococcus pneumoniae DNA polymerase I lacks 3'-to-5' exonuclease activity: localization of the 5'-to-3' exonucleolytic domain

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Bacteriophage T4 RNase H removes both RNA primers and adjacent DNA from the 5' end of lagging strand fragments

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Flexible loops and helical arches

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Crystal structure of Thermus aquaticus DNA polymerase

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Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins

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A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

21 January 2018

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The crystal structure of flap endonuclease-1 from Methanococcus jannaschii

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Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

21 January 2018

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Molecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshii

21 January 2018

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Purification and properties of the 5′‐3′ exonuclease D190 ←A mutant of DNA polymerase I from Streptococcus pneumoniae

21 January 2018

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Deoxy- and dideoxynucleotide discrimination and identification of critical 5' nuclease domain residues of the DNA polymerase I from Mycobacterium tuberculosis

21 January 2018

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Biochemical and mutational studies of the 5'-3' exonuclease of DNA polymerase I of Escherichia coli

21 January 2018

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Contacts between the 5' nuclease of DNA polymerase I and its DNA substrate.

21 January 2018

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Functional analysis of point mutations in human flap endonuclease-1 active site

21 January 2018

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Biochemical analysis of point mutations in the 5'-3' exonuclease of DNA polymerase I of Streptococcus pneumoniae. Functional and structural implications.

21 January 2018

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Dynamic evidence for metal ion catalysis in the reaction mediated by a flap endonuclease.

21 January 2018

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Calorimetric techniques in the study of high-order DNA-drug interactions

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Rapid measurement of binding constants and heats of binding using a new titration calorimeter

21 January 2018

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Distinct roles of two Mg2+ binding sites in regulation of murine flap endonuclease-1 activities

21 January 2018

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Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1.

21 January 2018

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Specific DNA recognition by EcoRV restriction endonuclease induced by calcium ions

21 January 2018

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A single-strand specific endonuclease activity copurifies with overexpressed T5 D15 exonuclease

21 January 2018

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Structure-specific DNA binding by bacteriophage T5 5'-->3' exonuclease.

21 January 2018

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Viral polymerase-associated 5'-->3'-exonucleases: expression, purification, and uses

21 January 2018

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Mutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavage

21 January 2018

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Preliminary crystallographic studies on the D15 5' to 3' exonuclease from phage T5.

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Metal Activation of Enzymes in Nucleic Acid Biochemistry

21 January 2018

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The characterization of a mammalian DNA structure-specific endonuclease

31 March 2020

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Structure-Specific Endonucleolytic Cleavage of Nucleic Acids by Eubacterial DNA Polymerases

31 March 2020

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Creation and Removal of Embedded Ribonucleotides in Chromosomal DNA during Mammalian Okazaki Fragment Processing

31 March 2020

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Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

31 March 2020

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Identification of Residues of T4 RNase H Required for Catalysis and DNA Binding

31 March 2020

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Calcium binding to calmodulin: effects of ionic strength, Mg2+, pH and temperature

31 March 2020

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Quantitative evaluation of metal ion binding to PvuII restriction endonuclease

31 March 2020

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33 Purification and properties of Neurospora crassa Endo-exonuclease, an Enzyme which can be converted to a single-strand specific endonuclease

31 March 2020

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The CCP4 suite: programs for protein crystallography

31 March 2020

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Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

31 March 2020

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NSMB754

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27 December 2019

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