Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity (Q22003979)

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5 December 2019

title

Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity (English)

1 reference

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5'-flap endonuclease activity

5 December 2019

main subject

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0017108

Flap structure-specific endonuclease 1

1 reference

GOA release 2020-03-11

DNA replication

1 reference

GOA release 2020-03-11

4

J A Tainer

J A

Tainer

1 reference

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5 December 2019

D J Hosfield

1

D J

Hosfield

1 reference

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5 December 2019

C D Mol

series ordinal

2

author given names

C D

author last names

Mol

1 reference

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5 December 2019

B Shen

series ordinal

3

author given names

B

author last names

Shen

1 reference

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5 December 2019

publication date

1 October 1998

1 reference

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5 December 2019

language of work or name

0 references

1 reference

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5 December 2019

volume

95

1 reference

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5 December 2019

issue

1

1 reference

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5 December 2019

page(s)

135-146

1 reference

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Enzymes and reactions at the eukaryotic DNA replication fork

5 December 2019

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Mechanism of tracking and cleavage of adduct-damaged DNA substrates by the mammalian 5'- to 3'-exonuclease/endonuclease RAD2 homologue 1 or flap endonuclease 1.

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Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

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Identification of Residues of T4 RNase H Required for Catalysis and DNA Binding

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A yeast replicative helicase, Dna2 helicase, interacts with yeast FEN-1 nuclease in carrying out its essential function

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A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

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p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex

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Defective transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G

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The helix-hairpin-helix DNA-binding motif: a structural basis for non-sequence-specific recognition of DNA.

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Expansion and Length-Dependent Fragility of CTG Repeats in Yeast

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The DNA repair endonuclease XPG binds to proliferating cell nuclear antigen (PCNA) and shares sequence elements with the PCNA-binding regions of FEN-1 and cyclin-dependent kinase inhibitor p21

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Repeat expansion--all in a flap?

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7 January 2021

Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

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7 January 2021

Crystal structure of E.coli RuvA with bound DNA Holliday junction at 6 Å resolution

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Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

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Requirement of the yeast RTH1 5' to 3' exonuclease for the stability of simple repetitive DNA.

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Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen

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Crystal structure of Thermus aquaticus DNA polymerase

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Involvement of flap endonuclease 1 in base excision DNA repair.

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7 January 2021

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

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7 January 2021

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

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7 January 2021

Structure-Specific Endonucleolytic Cleavage of Nucleic Acids by Eubacterial DNA Polymerases

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Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins

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7 January 2021

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7 January 2021

Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage

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XPG endonuclease makes the 3' incision in human DNA nucleotide excision repair

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Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

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Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9778254%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017