Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target (Q38326252)

2 September 2017

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target (English)

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2 September 2017

1

Roberto Chiarle

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2 September 2017

9

Giorgio Inghirami

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2 September 2017

William J Simmons

2

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2 September 2017

Honjying Cai

3

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2 September 2017

Girish Dhall

4

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2 September 2017

Alberto Zamo

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2 September 2017

Regina Raz

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2 September 2017

James G Karras

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2 September 2017

David E Levy

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2 September 2017

language of work or name

English

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publication date

15 May 2005

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2 September 2017

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11

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2 September 2017

623-629

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6

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https://scigraph.springernature.com/pub.10.1038/nm1249

2 September 2017

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cites work

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

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7 January 2021

Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas

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7 January 2021

Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity

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7 January 2021

NPM-ALK transgenic mice spontaneously develop T-cell lymphomas and plasma cell tumors.

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7 January 2021

Translocations involving anaplastic lymphoma kinase (ALK).

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7 January 2021

Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death

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7 January 2021

STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription

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7 January 2021

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

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7 January 2021

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma

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7 January 2021

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7 January 2021

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo

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7 January 2021

Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis

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7 January 2021

Essential role of STAT3 for embryonic stem cell pluripotency

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7 January 2021

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

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7 January 2021

The Hallmarks of Cancer

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7 January 2021

Chronic Myeloid Leukemia — Advances in Biology and New Approaches to Treatment

1 reference

7 January 2021

The role of STATs in transcriptional control and their impact on cellular function

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7 January 2021

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

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7 January 2021

STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation

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7 January 2021

Specific inhibition of PTEN expression reverses hyperglycemia in diabetic mice

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7 January 2021

Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors

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7 January 2021

Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice

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7 January 2021

ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma.

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7 January 2021

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2

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7 January 2021

Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells

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7 January 2021

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

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7 January 2021

Stat3 activation is required for cellular transformation by v-src

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7 January 2021

Expression of ALK1 and p80 in inflammatory myofibroblastic tumor and its mesenchymal mimics: a study of 135 cases

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7 January 2021

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

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7 January 2021

B lymphocyte-specific, Cre-mediated mutagenesis in mice

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7 January 2021

Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

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7 January 2021

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

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7 January 2021

Differential regulation of constitutive major histocompatibility complex class I expression in T and B lymphocytes

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7 January 2021

Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation

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7 January 2021

Identifiers

DOI

10.1038/NM1249

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2 September 2017

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