Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells (Q38359739)

2 September 2017

Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells (English)

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2 September 2017

Mei Huang

1

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2 September 2017

Jay F Dorsey

2

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2 September 2017

P K Epling-Burnette

3

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2 September 2017

Ramadevi Nimmanapalli

4

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2 September 2017

Terry H Landowski

5

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2 September 2017

Linda B Mora

6

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2 September 2017

Guilian Niu

7

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2 September 2017

Dominic Sinibaldi

8

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2 September 2017

Fanqi Bai

9

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2 September 2017

Alan Kraker

10

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2 September 2017

Hua Yu

11

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2 September 2017

Lynn Moscinski

12

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2 September 2017

Sheng Wei

13

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2 September 2017

Julie Djeu

14

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2 September 2017

William S Dalton

15

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2 September 2017

Kapil Bhalla

16

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2 September 2017

Thomas P Loughran

17

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2 September 2017

Jie Wu

18

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2 September 2017

Richard Jove

19

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2 September 2017

language of work or name

English

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publication date

1 December 2002

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2 September 2017

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2 September 2017

21

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2 September 2017

57

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2 September 2017

8804-8816

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206028

2 September 2017

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cites work

Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

Direct tumor lysis by NK cells uses a Ras-independent mitogen-activated protein kinase signal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

Differential complementation of Bcr-Abl point mutants with c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

1 reference

7 January 2021

The role of STATs in transcriptional control and their impact on cellular function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Stat3 activation is required for cellular transformation by v-src

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

1 reference

7 January 2021

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

The role of STATs in myeloid differentiation and leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Jak-STAT signaling induced by the v-abl oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

JAK-STAT signaling activated by Abl oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Function of the c-Myc oncogenic transcription factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Interleukin-3 protects Bcr-Abl-transformed hematopoietic progenitor cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Cooperative regulation of Mcl-1 by Janus kinase/stat and phosphatidylinositol 3-kinase contribute to granulocyte-macrophage colony-stimulating factor-delayed apoptosis in human neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: cooperation of akt with raf/erk leads to p65 nuclear factor kappaB-mediated antiapoptosis involving c-IAP2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Adhesion to fibronectin via beta1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Bcr-Abl kinase promotes cell cycle entry of primary myeloid CML cells in the absence of growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

CRKL binding to BCR-ABL and BCR-ABL transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

STAT signaling in the pathogenesis and treatment of leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Transformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective Hck

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Activation of STAT3 by the c-Fes protein-tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Co-treatment with As2O3 enhances selective cytotoxic effects of STI-571 against Brc-Abl-positive acute leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

CrkL functions as a nuclear adaptor and transcriptional activator in Bcr-Abl-expressing cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Dominant negative MYC blocks transformation by ABL oncogenes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Control of myeloid differentiation and survival by Stats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

STAT signaling in head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Stat3 plays an important role in oncogenic Ros- and insulin-like growth factor I receptor-induced anchorage-independent growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206028

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206028

1 reference

Dimensions Publication ID

2 September 2017

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1 reference