Non-histone protein methylation as a regulator of cellular signalling and function (Q38285792)

1 September 2017

1 reference

title

Non-histone protein methylation as a regulator of cellular signalling and function (English)

1 reference

1 September 2017

Kyle K Biggar

1

1 reference

PubMed ID

25491103

1 September 2017

Shawn S-C Li

series ordinal

2

1 reference

1 September 2017

10 December 2014

1 reference

Nature Reviews Molecular Cell Biology

1 September 2017

1 reference

1 September 2017

16

1 reference

1 September 2017

5-17

1 reference

1 September 2017

1

1 reference

https://scigraph.springernature.com/pub.10.1038/nrm3915

1 September 2017

0 references

cites work

ɛ-N-Methyl-lysine in Bacterial Flagellar Protein

1 reference

THE OCCURRENCE OF EPSILON-N-METHYL LYSINE IN HISTONES

31 March 2020

1 reference

An activity phosphorylating tyrosine in polyoma T antigen immunoprecipitates

31 March 2020

1 reference

The language of covalent histone modifications

31 March 2020

1 reference

Histone methylation: a dynamic mark in health, disease and inheritance

31 March 2020

1 reference

Charting histone modifications and the functional organization of mammalian genomes

31 March 2020

1 reference

The complex language of chromatin regulation during transcription

31 March 2020

1 reference

High-resolution profiling of histone methylations in the human genome

31 March 2020

1 reference

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

31 March 2020

1 reference

Cancer epigenomics: DNA methylomes and histone-modification maps

31 March 2020

1 reference

DNA methylation and histone modifications: teaming up to silence genes

31 March 2020

1 reference

Historical review: the field of protein methylation

31 March 2020

1 reference

Protein methylation and DNA repair

31 March 2020

1 reference

Chemical mechanisms of histone lysine and arginine modifications

31 March 2020

1 reference

Arginine methylation an emerging regulator of protein function

31 March 2020

1 reference

Deciphering arginine methylation: Tudor tells the tale.

31 March 2020

1 reference

Src homology region 2 domains direct protein-protein interactions in signal transduction

31 March 2020

1 reference

SH2 domain specificity and activity modified by a single residue

31 March 2020

1 reference

Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain

31 March 2020

1 reference

Temporal regulation of EGF signalling networks by the scaffold protein Shc1

31 March 2020

1 reference

Tudor: a versatile family of histone methylation 'readers'.

31 March 2020

1 reference

Histone lysine methylation dynamics: establishment, regulation, and biological impact

31 March 2020

1 reference

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

31 March 2020

1 reference

Readers of histone methylarginine marks.

31 March 2020

1 reference

Role for 53BP1 Tudor domain recognition of p53 dimethylated at lysine 382 in DNA damage signaling

31 March 2020

1 reference

p53 is regulated by the lysine demethylase LSD1

31 March 2020

1 reference

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

31 March 2020

1 reference

The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors

31 March 2020

1 reference

Epigenetic protein families: a new frontier for drug discovery

31 March 2020

1 reference

Protein arginine methyltransferases and cancer

31 March 2020

1 reference

Tyrosine phosphorylation mapping of the epidermal growth factor receptor signaling pathway

31 March 2020

1 reference

Mass spectrometry mapping of epidermal growth factor receptor phosphorylation related to oncogenic mutations and tyrosine kinase inhibitor sensitivity

31 March 2020

1 reference

A histone methylation network regulates transgenerational epigenetic memory in C. elegans

31 March 2020

1 reference

Histone methyltransferase MLL3 contributes to genome-scale circadian transcription

31 March 2020

1 reference

Dynamic methylation of Numb by Set8 regulates its binding to p53 and apoptosis

31 March 2020

1 reference

A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response

31 March 2020

1 reference

Proteome-wide enrichment of proteins modified by lysine methylation.

31 March 2020

1 reference

Identification and characterization of lysine-methylated sites on histones and non-histone proteins

31 March 2020

1 reference

Methylation-mediated regulation of E2F1 in DNA damage-induced cell death

31 March 2020

1 reference

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

31 March 2020

1 reference

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

31 March 2020

1 reference

SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer

31 March 2020

1 reference

The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity

31 March 2020

1 reference

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

31 March 2020

1 reference

Concerted activities of distinct H4K20 methyltransferases at DNA double-strand breaks regulate 53BP1 nucleation and NHEJ-directed repair

31 March 2020

1 reference

Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage

31 March 2020

1 reference

The growing landscape of lysine acetylation links metabolism and cell signalling

31 March 2020

1 reference

Immunoaffinity enrichment and mass spectrometry analysis of protein methylation

31 March 2020

1 reference

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

31 March 2020

1 reference

A general molecular affinity strategy for global detection and proteomic analysis of lysine methylation

31 March 2020

1 reference

Mass spectrometry-based identification and characterisation of lysine and arginine methylation in the human proteome.

31 March 2020

1 reference

Large-scale global identification of protein lysine methylation in vivo

31 March 2020

1 reference

Identifying and quantifying in vivo methylation sites by heavy methyl SILAC

31 March 2020

1 reference

Purification and functional characterization of a histone H3-lysine 4-specific methyltransferase.

31 March 2020

1 reference

Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

31 March 2020

1 reference

Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor

31 March 2020

1 reference

Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

31 March 2020

1 reference

Methylation of SPT5 Regulates Its Interaction with RNA Polymerase II and Transcriptional Elongation Properties

31 March 2020

1 reference

Arginine methylation of Sam68 and SLM proteins negatively regulates their poly(U) RNA binding activity

31 March 2020

1 reference

Ribosomal protein rpS2 is hypomethylated in PRMT3-deficient mice.

31 March 2020

1 reference

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

31 March 2020

1 reference

Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I.

31 March 2020

1 reference

An unexpected journey: lysine methylation across the proteome

31 March 2020

1 reference

Crosstalk between ubiquitin and other post-translational modifications on chromatin during double-strand break repair

31 March 2020

1 reference

Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt.

31 March 2020

1 reference

An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation

31 March 2020

1 reference

A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability

31 March 2020

1 reference

The nuclear factor NF-kappaB pathway in inflammation

31 March 2020

1 reference

Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

31 March 2020

1 reference

Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling

31 March 2020

1 reference

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

31 March 2020

1 reference

Lysine methylation regulates the pRb tumour suppressor protein

31 March 2020

1 reference

Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation

31 March 2020

1 reference

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

31 March 2020

1 reference

Arginine/lysine-methyl/methyl switches: biochemical role of histone arginine methylation in transcriptional regulation

31 March 2020

1 reference

p53 post-translational modification: deregulated in tumorigenesis

31 March 2020

1 reference

Arginine methylation regulates the p53 response

31 March 2020

1 reference

Lysine-specific modifications of p53: a matter of life and death?

31 March 2020

1 reference

Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage

31 March 2020

1 reference

Repression of p53 activity by Smyd2-mediated methylation

31 March 2020

1 reference

Regulation of p53 activity through lysine methylation

31 March 2020

1 reference

Structural Insight into p53 Recognition by the 53BP1 Tandem Tudor Domain

31 March 2020

1 reference

The MBT Repeats of L3MBTL1 Link SET8-mediated p53 Methylation at Lysine 382 to Target Gene Repression

31 March 2020

1 reference

PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53

31 March 2020

1 reference

Modulation of p53 function by SET8-mediated methylation at lysine 382

31 March 2020

1 reference

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

31 March 2020

1 reference

Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF

31 March 2020

1 reference

Lysine methylation promotes VEGFR-2 activation and angiogenesis

31 March 2020

1 reference

Crosstalk between Arg 1175 methylation and Tyr 1173 phosphorylation negatively modulates EGFR-mediated ERK activation

31 March 2020

1 reference

Bone morphogenetic proteins

31 March 2020

1 reference

Does Smad6 methylation control BMP signaling in cancer?

31 March 2020

1 reference

TGF-beta and the Smad signal transduction pathway

31 March 2020

1 reference

LRP5 and LRP6 in development and disease

31 March 2020

1 reference

Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling

31 March 2020

1 reference

GSK3: a multifaceted kinase in Wnt signaling

31 March 2020

1 reference

The β-catenin destruction complex

31 March 2020

1 reference

Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2.

31 March 2020

1 reference

Dishevelled3 is a novel arginine methyl transferase substrate

31 March 2020

1 reference

Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA

31 March 2020

1 reference

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

31 March 2020

1 reference

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

31 March 2020

1 reference

Control of the hippo pathway by Set7-dependent methylation of Yap.

31 March 2020

1 reference

Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cells

31 March 2020

1 reference

Characterization of molecular recognition of STAT3 SH2 domain inhibitors through molecular simulation.

31 March 2020

1 reference

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

31 March 2020

1 reference

Regulation of chromatin by histone modifications

31 March 2020

1 reference

Chromatin remodeling at DNA double-strand breaks

31 March 2020

1 reference

Double-strand break repair: 53BP1 comes into focus

31 March 2020

1 reference

Push back to respond better: regulatory inhibition of the DNA double-strand break response

31 March 2020

1 reference

The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks

31 March 2020

1 reference

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

31 March 2020

1 reference

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

31 March 2020

1 reference

The p53 network: cellular and systemic DNA damage responses in aging and cancer

31 March 2020

1 reference

Mdm2 promotes the rapid degradation of p53

31 March 2020

1 reference

NUMB controls p53 tumour suppressor activity

31 March 2020

1 reference

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation

31 March 2020

1 reference

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage

31 March 2020

1 reference

Mass-spectrometry-based draft of the human proteome

31 March 2020

1 reference

A draft map of the human proteome

31 March 2020

1 reference

Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directions

31 March 2020

1 reference

Mass spectrometry-based proteomics

31 March 2020

1 reference

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor

31 March 2020

1 reference

Linear Motif Atlas for Phosphorylation-Dependent Signaling

31 March 2020

1 reference

NetworKIN: a resource for exploring cellular phosphorylation networks

31 March 2020

1 reference

Targeting protein lysine methylation and demethylation in cancers.

31 March 2020

1 reference

Targeting histone lysine demethylases - progress, challenges, and the future

31 March 2020

1 reference

Histone lysine methylation and demethylation pathways in cancer

31 March 2020

1 reference

12 December 2020

The enzymatic phosphorylation of proteins

1 reference

12 December 2020

The intersection between DNA damage response and cell death pathways

1 reference

12 December 2020

Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion

1 reference

12 December 2020

DNA double strand break repair via non-homologous end-joining

1 reference

12 December 2020

Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins

1 reference

12 December 2020

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

1 reference

12 December 2020

Prediction of phosphotyrosine signaling networks using a scoring matrix-assisted ligand identification approach

1 reference

12 December 2020

JAK-STAT3 and somatic cell reprogramming

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM3915

1 reference

PubMed ID

25491103

Dimensions Publication ID

1 September 2017

0 references

1 reference

PubMed ID

25491103