The growing landscape of lysine acetylation links metabolism and cell signalling (Q38232935)

31 August 2017

The growing landscape of lysine acetylation links metabolism and cell signalling (English)

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31 August 2017

4

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31 August 2017

Brian T Weinert

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author name string

Chunaram Choudhary

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1

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31 August 2017

Yuya Nishida

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31 August 2017

Matthias Mann

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31 August 2017

1 August 2014

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Nature Reviews Molecular Cell Biology

31 August 2017

15

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based on heuristic

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published in

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31 August 2017

15

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31 August 2017

536-550

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31 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrm3841

31 August 2017

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Calorie restriction alters mitochondrial protein acetylation

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Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III

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MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

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Methylation-acetylation interplay activates p53 in response to DNA damage

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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Acetylation-dependent signal transduction for type I interferon receptor

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Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

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MYST protein acetyltransferase activity requires active site lysine autoacetylation

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Kinetic and mass spectrometric analysis of p300 histone acetyltransferase domain autoacetylation.

21 January 2018

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The SIRT2 deacetylase regulates autoacetylation of p300

21 January 2018

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Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer

21 January 2018

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Acetylation-dependent regulation of Skp2 function

21 January 2018

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Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase is regulated by acetylation

21 January 2018

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A brief introduction to FOXOlogy

21 January 2018

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

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Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

21 January 2018

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SIRT2 regulates adipocyte differentiation through FoxO1 acetylation/deacetylation

21 January 2018

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Advances in characterizing ubiquitylation sites by mass spectrometry.

21 January 2018

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Nepsilon-formylation of lysine is a widespread post-translational modification of nuclear proteins occurring at residues involved in regulation of chromatin function

21 January 2018

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Probing the active site of homoserine trans-succinylase

21 January 2018

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Identification of lysine succinylation as a new post-translational modification

21 January 2018

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The first identification of lysine malonylation substrates and its regulatory enzyme

21 January 2018

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N-lysine propionylation controls the activity of propionyl-CoA synthetase

21 January 2018

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Lysine propionylation and butyrylation are novel post-translational modifications in histones

21 January 2018

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Molecular characterization of propionyllysines in non-histone proteins

21 January 2018

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Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

21 January 2018

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Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

21 January 2018

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Identification and verification of lysine propionylation and butyrylation in yeast core histones using PTMap software

21 January 2018

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The human histone acetyltransferase P/CAF is a promiscuous histone propionyltransferase.

21 January 2018

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Catalytic mechanism of a MYST family histone acetyltransferase

21 January 2018

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Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

21 January 2018

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A map of general and specialized chromatin readers in mouse tissues generated by label-free interaction proteomics.

21 January 2018

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Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers

21 January 2018

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Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

21 January 2018

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SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks

21 January 2018

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SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways

21 January 2018

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Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli

21 January 2018

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Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

21 January 2018

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SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

21 January 2018

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Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

21 January 2018

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SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine

21 January 2018

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Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins

21 January 2018

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Genetically encoding N(epsilon)-acetyllysine in recombinant proteins.

21 January 2018

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Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization

21 January 2018

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Inactivating mutations of acetyltransferase genes in B-cell lymphoma

21 January 2018

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CREBBP mutations in relapsed acute lymphoblastic leukaemia

21 January 2018

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Histone deacetylases and cancer: causes and therapies

21 January 2018

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

21 January 2018

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Selective inhibition of BET bromodomains

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Small-molecule inhibition of BRDT for male contraception

21 January 2018

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A protease for 'middle-down' proteomics

21 January 2018

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Bioorthogonal chemical reporters for monitoring protein acetylation

21 January 2018

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The many faces of insulin-like peptide signalling in the brain

21 January 2018

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Quantitative assessment of the impact of the gut microbiota on lysine epsilon-acetylation of host proteins using gnotobiotic mice

21 January 2018

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Circadian acetylome reveals regulation of mitochondrial metabolic pathways

21 January 2018

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Monoclonal antibody cocktail as an enrichment tool for acetylome analysis

21 January 2018

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Cyclophilin D modulates mitochondrial acetylome

21 January 2018

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The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching

21 January 2018

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Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation

21 January 2018

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The acetylproteome of Gram-positive model bacterium Bacillus subtilis.

21 January 2018

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Chlamydomonas alpha-tubulin is posttranslationally modified by acetylation on the epsilon-amino group of a lysine

21 January 2018

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Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity

31 March 2020

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Pervasive combinatorial modification of histone H3 in human cells

31 March 2020

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Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ.

31 March 2020

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Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases

31 March 2020

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A two-way street: reciprocal regulation of metabolism and signalling.

31 March 2020

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Nonenzymatic acetylation of histones with acetyl-CoA

31 March 2020

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Posttranslational modification of p53: cooperative integrators of function

31 March 2020

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Formation of Nepsilon-(succinyl)lysine in vivo: a novel marker for docosahexaenoic acid-derived protein modification

31 March 2020

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Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism

31 March 2020

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Sirtuins as regulators of metabolism and healthspan

31 March 2020

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SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM3841

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Dimensions Publication ID

31 August 2017

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