Role of SIRT1 in autoimmune demyelination and neurodegeneration (Q38256576)

1 September 2017

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title

Role of SIRT1 in autoimmune demyelination and neurodegeneration (English)

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1 September 2017

Alvaro Martin

1

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1 September 2017

Cosmin A Tegla

2

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1 September 2017

Cornelia D Cudrici

3

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1 September 2017

Adam M Kruszewski

4

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1 September 2017

Philippe Azimzadeh

5

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1 September 2017

Dallas Boodhoo

6

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1 September 2017

Armugam P Mekala

7

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1 September 2017

Violeta Rus

8

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1 September 2017

Horea Rus

9

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1 September 2017

1 March 2015

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1 September 2017

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1 September 2017

61

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1 September 2017

3

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1 September 2017

187-197

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https://scigraph.springernature.com/pub.10.1007/s12026-014-8557-5

1 September 2017

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cites work

Roles of histone acetyltransferases and deacetylases in gene regulation

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Histone deacetylases: salesmen and customers in the post-translational modification market.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirtuins (histone deacetylases III) in the cellular response to DNA damage--facts and hypotheses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1, is it a tumor promoter or tumor suppressor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Histone deacetylases and their role in motor neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Histone deacetylases and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Regulation of histone deacetylase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Epigenetic modifications induced by RGC-32 in colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

dSir2 and longevity in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Therapeutic potential of activators and inhibitors of sirtuins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Biochemical effects of SIRT1 activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Rationale for the use of histone deacetylase inhibitors as a dual therapeutic modality in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Molecular cloning and characterization of RGC-32, a novel gene induced by complement activation in oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

B cells in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Molecular pathways: emerging roles of mammalian Sirtuin SIRT7 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Tissue-specific regulation of SIRT1 by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The role of sirtuins in modulating redox stressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Evidence for a common mechanism of SIRT1 regulation by allosteric activators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

JNK1 phosphorylates SIRT1 and promotes its enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 and other sirtuins in metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The NAD+ precursor nicotinamide governs neuronal survival during oxidative stress through protein kinase B coupled to FOXO3a and mitochondrial membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Small molecule SIRT1 activators for the treatment of aging and age-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 is decreased during relapses in patients with multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The many faces of insulin-like peptide signalling in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRTUIN 1: regulating the regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirtuins' modulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

FoxO1 mediates an autofeedback loop regulating SIRT1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Phosphorylation regulates SIRT1 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The ways and means that fine tune Sirt1 activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

DBC1 is a negative regulator of SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Antimicrobial effect of resveratrol on dermatophytes and bacterial pathogens of the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Brain SIRT1: anatomical distribution and regulation by energy availability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Protective effects and mechanisms of sirtuins in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The neurobiology of sirtuins and their role in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 and neuronal diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Neurogenic responses to amyloid-beta plaques in the brain of Alzheimer's disease-like transgenic (pPDGF-APPSw,Ind) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Deacetylation of p53 modulates its effect on cell growth and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirtuin deacetylases in neurodegenerative diseases of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

2012 Alzheimer's disease facts and figures

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

The amyloid pathology progresses in a neurotransmitter-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Protective effect of resveratrol on beta-amyloid-induced oxidative PC12 cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Synergistic protection of PC12 cells from beta-amyloid toxicity by resveratrol and catechin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Neuronal protection by sirtuins in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Epidemiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Classic and new animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 protects against α-synuclein aggregation by activating molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Mechanisms of synaptic dysfunction and excitotoxicity in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Cell-based therapies for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Multiple sclerosis--the plaque and its pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Neuroprotective effects of the complement terminal pathway during demyelination: implications for oligodendrocyte survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Using EAE to better understand principles of immune function and autoimmune pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirtuins in mammals: insights into their biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

SIRT1 activation confers neuroprotection in experimental optic neuritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirt1 contributes critically to the redox-dependent fate of neural progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Oral resveratrol reduces neuronal damage in a model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Resveratrol neuroprotection in a chronic mouse model of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Decreased severity of experimental autoimmune encephalomyelitis during resveratrol administration is associated with increased IL-17+IL-10+ T cells, CD4(-) IFN-gamma+ cells, and decreased macrophage IL-6 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis, primarily via induction of apoptosis in T cells involving activation of aryl hydrocarbon receptor and estrogen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Role of C5b-9 complement complex and response gene to complement-32 (RGC-32) in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Dual role of Response gene to complement-32 in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12026-014-8557-5

Sirtuins as regulators of metabolism and healthspan

21 January 2018

1 reference

12 December 2020

Characterization of two genes required for the position-effect control of yeast mating-type genes

1 reference

12 December 2020

Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae

1 reference

12 December 2020

Histone acetylation and an epigenetic code

1 reference

12 December 2020

The LXXLL motif of murine forkhead transcription factor FoxO1 mediates Sirt1-dependent transcriptional activity

1 reference

12 December 2020

1 reference

12 December 2020

Sirtuins in neurodegenerative diseases: an update on potential mechanisms.

1 reference

12 December 2020

The emerging and diverse roles of sirtuins in cancer: a clinical perspective

1 reference

12 December 2020

MAR1-a Regulator of the HMa and HMalpha Loci in SACCHAROMYCES CEREVISIAE

1 reference

12 December 2020

Overexpression of SIRT1 protein in neurons protects against experimental autoimmune encephalomyelitis through activation of multiple SIRT1 targets

1 reference

12 December 2020

Structure and function of poly(ADP-ribose) polymerase-1: role in oxidative stress-related pathologies

1 reference

12 December 2020

10.1007/S12026-014-8557-5

Identifiers

DOI

1 reference

Dimensions Publication ID

1 September 2017

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1 reference