Evidence for a common mechanism of SIRT1 regulation by allosteric activators (Q28286859)

Thomas V Riera

7

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Anabela Pinto Rolo

Anabela P Rolo

24

0 references

David A. Sinclair

David A Sinclair

30

0 references

Dudley W Lamming

Dudley W Lamming

10

0 references

Basil P Hubbard

Basil P Hubbard

1

0 references

Bradley L. Pentelute

11

Bradley L Pentelute

0 references

Joel Moss

26

Joel Moss

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author name string

Ana P Gomes

2

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Han Dai

3

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Jun Li

4

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April W Case

5

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Thomas Considine

6

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Sook Yen E

9

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Eli R Schuman

12

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Linda A Stevens

13

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Alvin J Y Ling

14

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Sean M Armour

15

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Shaday Michan

16

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Huizhen Zhao

17

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Yong Jiang

18

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Sharon M Sweitzer

19

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Charles A Blum

20

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Jeremy S Disch

21

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Pui Yee Ng

22

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Konrad T Howitz

23

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Yoshitomo Hamuro

25

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Robert B Perni

27

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James L Ellis

28

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George P Vlasuk

From sirtuin biology to human diseases: an update

29

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language of work or name

English

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publication date

8 March 2013

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published in

Science

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volume

339

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page(s)

1216-9

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issue

6124

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SRT1720 improves survival and healthspan of obese mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activator

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Resveratrol is not a direct activator of SIRT1 enzyme activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

CBP/p300-mediated acetylation of histone H3 on lysine 56

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Resveratrol improves health and survival of mice on a high-calorie diet

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Mechanism of human SIRT1 activation by resveratrol

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Substrate-specific activation of sirtuins by resveratrol

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Mammalian sirtuins: biological insights and disease relevance

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SIRT1 associates with eIF2-alpha and regulates the cellular stress response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Sirtuins mediate mammalian metabolic responses to nutrient availability

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

SIRT1 contains N- and C-terminal regions that potentiate deacetylase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Peptide switch is essential for Sirt1 deacetylase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

The biochemistry of sirtuins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Identification and functional analysis of the Saccharomyces cerevisiae nicotinamidase gene, PNC1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3799917

Fluorogenic reaction and specific microdetermination of ammonia

2 June 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23471411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1231097

1 reference

release_zxcdcrz43fd6vnk7m2begldg2i

1374437

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zxcdcrz43fd6vnk7m2begldg2i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1374437

1 reference

1 reference

1 reference