Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics (Q38209232)

31 August 2017

Eph- and ephrin-dependent mechanisms in tumor and stem cell dynamics (English)

1 reference

31 August 2017

Erika Gucciardo

1

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Kaisa Lehti

object named as

Kaisa Lehti

series ordinal

3

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author name string

Nami Sugiyama

series ordinal

2

1 reference

31 August 2017

4 May 2014

1 reference

Cellular and Molecular Life Sciences

31 August 2017

1 reference

31 August 2017

71

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31 August 2017

3685-3710

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31 August 2017

19

1 reference

https://scigraph.springernature.com/pub.10.1007/s00018-014-1633-0

31 August 2017

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Soluble ephrin a1 is necessary for the growth of HeLa and SK-BR3 cells

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EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin

21 January 2018

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Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse

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Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins

21 January 2018

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Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion

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Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans

21 January 2018

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EphA2 cleavage by MT1-MMP triggers single cancer cell invasion via homotypic cell repulsion

21 January 2018

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Unified Nomenclature for Eph Family Receptors and Their Ligands, the Ephrins

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cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases

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Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors

21 January 2018

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Dancing with the dead: Eph receptors and their kinase-null partners

21 January 2018

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Crystal structure of an ephrin ectodomain

21 January 2018

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'Eph'ective signaling: forward, reverse and crosstalk

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Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.

21 January 2018

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EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt

21 January 2018

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Concepts and consequences of Eph receptor clustering

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Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex

21 January 2018

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Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling

21 January 2018

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Biological and structural characterization of glycosylation on ephrin-A1, a preferred ligand for EphA2 receptor tyrosine kinase

21 January 2018

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Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5

21 January 2018

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An extracellular steric seeding mechanism for Eph-ephrin signaling platform assembly

21 January 2018

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Oligomeric structure of the human EphB2 receptor SAM domain

21 January 2018

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Dissecting the EphA3/Ephrin-A5 interactions using a novel functional mutagenesis screen

21 January 2018

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Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.

21 January 2018

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Eph receptor function is modulated by heterooligomerization of A and B type Eph receptors

21 January 2018

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Identification of the Jak/Stat proteins as novel downstream targets of EphA4 signaling in muscle: implications in the regulation of acetylcholinesterase expression

21 January 2018

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EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis

21 January 2018

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Ephrin-B1 Reverse Signaling Activates JNK through a Novel Mechanism That Is Independent of Tyrosine Phosphorylation

21 January 2018

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The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain

21 January 2018

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PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

21 January 2018

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PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands

21 January 2018

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Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion

21 January 2018

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Ephrin signaling: One raft to rule them all? One raft to sort them? One raft to spread their call and in signaling bind them?

21 January 2018

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Lipid rafts and signal transduction

21 January 2018

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Eph, a protein family coming of age: more confusion, insight, or complexity?

21 January 2018

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Recruitment of Eph receptors into signaling clusters does not require ephrin contact

21 January 2018

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Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrins are not only unattractive

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A conditional feedback loop regulates Ras activity through EphA2.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Constitutive activation of the Raf-MAPK pathway causes negative feedback inhibition of Ras-PI3K-AKT and cellular arrest through the EphA2 receptor

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Attenuation of eph receptor kinase activation in cancer cells by coexpressed ephrin ligands

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cytoplasmic relaxation of active Eph controls ephrin shedding by ADAM10

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB-ephrinB bi-directional endocytosis terminates adhesion allowing contact mediated repulsion.

21 January 2018

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B61 is a ligand for the ECK receptor protein-tyrosine kinase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Regulated cleavage of a contact-mediated axon repellent

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Tissue transglutaminase clusters soluble A-type ephrins into functionally active high molecular weight oligomers.

21 January 2018

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Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity

21 January 2018

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Decreased tumorigenic potential of EphA2-overexpressing breast cancer cells following treatment with adenoviral vectors that express EphrinA1.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Caveolin-1 is required for signaling and membrane targeting of EphB1 receptor tyrosine kinase

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Reverse endocytosis of transmembrane ephrin-B ligands via a clathrin-mediated pathway.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

PTP1B regulates Eph receptor function and trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Elevated protein tyrosine phosphatase activity provokes Eph/ephrin-facilitated adhesion of pre-B leukemia cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-A1 induces c-Cbl phosphorylation and EphA receptor down-regulation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Vav family GEFs link activated Ephs to endocytosis and axon guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephexin4-mediated promotion of cell migration and anoikis resistance is regulated by serine 897 phosphorylation of EphA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-A5 modulates cell adhesion and morphology in an integrin-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Tyrosine phosphorylation of transmembrane ligands for Eph receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The C-terminus of ephrin-B1 regulates metalloproteinase secretion and invasion of cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B3 ligand promotes glioma invasion through activation of Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphrinB1 controls cell-cell junctions through the Par polarity complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B2 regulates endothelial cell morphology and motility independently of Eph-receptor binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Receptor tyrosine kinase EphB4 is a survival factor in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ligand-independent activation of EphA2 by arachidonic acid induces metastasis-like behaviour in prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The interplay between Src family kinases and receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Src is required for cell migration and shape changes induced by fibroblast growth factor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Syk, c-Src, the alphavbeta3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The EphB4 receptor-tyrosine kinase promotes the migration of melanoma cells through Rho-mediated actin cytoskeleton reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 induces metastatic growth regulating amoeboid motility and clonogenic potential in prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 bears plasticity to tumor invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Expression profile of Eph receptors and ephrin ligands in human skin and downregulation of EphA1 in nonmelanoma skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 is a critical oncogene in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Expression of Ephb2 and Ephb4 in breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Potential clinical relevance of Eph receptors and ephrin ligands expressed in prostate carcinoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

High-level expression of EphA2 receptor tyrosine kinase in prostatic intraepithelial neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Mechanisms and functions of Eph and ephrin signalling

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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Classifying collective cancer cell invasion

21 January 2018

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EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion

21 January 2018

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Eph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Aberrant DNA methylation and epigenetic inactivation of Eph receptor tyrosine kinases and ephrin ligands in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Competition amongst Eph receptors regulates contact inhibition of locomotion and invasiveness in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB6-null mutation results in compromised T cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA and ephrin-A proteins regulate integrin-mediated T lymphocyte interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cell polarity and cancer--cell and tissue polarity as a non-canonical tumor suppressor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Epithelial cell polarity: a major gatekeeper against cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cell polarity as a regulator of cancer cell behavior plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA4 activity causes cell shape change and a loss of cell polarity in Xenopus laevis embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA kinase activation regulates HGF-induced epithelial branching morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 engages Git1 to suppress Arf6 activity modulating epithelial cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 phosphorylates the cytoplasmic tail of Claudin-4 and mediates paracellular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Polarity proteins in migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Rac and Rho GTPases in cancer cell motility control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cancer invasion and the microenvironment: plasticity and reciprocity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin A5 expression promotes invasion and transformation of murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

An Eph receptor regulates integrin activity through R-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphrinA1 activates a Src/focal adhesion kinase-mediated motility response leading to rho-dependent actino/myosin contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cooperation between integrins and growth factor receptors in signaling and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Integrin signalling during tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

FAK integrates growth-factor and integrin signals to promote cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Activated R-ras, Rac1, PI 3-kinase and PKCepsilon can each restore cell spreading inhibited by isolated integrin beta1 cytoplasmic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cell migration: Rho GTPases lead the way

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Lysophosphatidic acid stimulates PC-3 prostate cancer cell Matrigel invasion through activation of RhoA and NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Membrane type 1-matrix metalloproteinase: substrate diversity in pericellular proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Matrix metalloproteinase-2 cleavage of the β1 integrin ectodomain facilitates colon cancer cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

MT1-MMP regulates VEGF-A expression through a complex with VEGFR-2 and Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Shedding of discoidin domain receptor 1 by membrane-type matrix metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Correction of ADAMTS13 deficiency by in utero gene transfer of lentiviral vector encoding ADAMTS13 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

When MT1-MMP meets ADAMs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Restriction of receptor movement alters cellular response: physical force sensing by EphA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Src-dependent phosphorylation of membrane type I matrix metalloproteinase on cytoplasmic tyrosine 573: role in endothelial and tumor cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Membrane-type-3 matrix metalloproteinase (MT3-MMP) functions as a matrix composition-dependent effector of melanoma cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Navigating ECM barriers at the invasive front: the cancer cell-stroma interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Invadopodia formation in oral squamous cell carcinoma: the role of epidermal growth factor receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Synaptic activity prompts gamma-secretase-mediated cleavage of EphA4 and dendritic spine formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Presenilin-dependent intramembrane cleavage of ephrin-B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ligand binding and calcium influx induce distinct ectodomain/gamma-secretase-processing pathways of EphB2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ligand-dependent EphB1 signaling suppresses glioma invasion and correlates with patient survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 as a novel molecular marker and target in glioblastoma multiforme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphrinA1 repulsive response is regulated by an EphA2 tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Receptor EphA2 activation with ephrinA1 suppresses growth of malignant mesothelioma (MM).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 as a promoter of melanoma tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Eph receptors and ephrin ligands: embryogenesis to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Overexpression of EPH receptor B2 in malignant mesothelioma correlates with oncogenic behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB receptor activity suppresses colorectal cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB4 promotes or suppresses Ras/MEK/ERK pathway in a context-dependent manner: Implications for EphB4 as a cancer target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Inhibition of retinal neovascularization by soluble EphA2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB4 controls blood vascular morphogenesis during postnatal angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

PDZ interaction site in ephrinB2 is required for the remodeling of lymphatic vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The ephrins and Eph receptors in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

New molecular pathways in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Vasculogenic mimicry and tumour-cell plasticity: lessons from melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Deciphering the signaling events that promote melanoma tumor cell vasculogenic mimicry and their link to embryonic vasculogenesis: role of the Eph receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB signaling controls lineage plasticity of adult neural stem cell niche cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Disruption of Eph/ephrin signaling affects migration and proliferation in the adult subventricular zone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphrinB3 is an anti-apoptotic ligand that inhibits the dependence receptor functions of EphA4 receptors during adult neurogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Embryonic stem cells express multiple Eph-subfamily receptor tyrosine kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Adult neurogenesis in the mammalian brain: significant answers and significant questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Forebrain ependymal cells are Notch-dependent and generate neuroblasts and astrocytes after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Regulation of neural progenitor cell state by ephrin-B

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA receptors direct the differentiation of mammalian neural precursor cells through a mitogen-activated protein kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A stem cell molecular signature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Primary human CD34+ hematopoietic stem and progenitor cells express functionally active receptors of neuromediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Ephrin receptor, EphB4, regulates ES cell differentiation of primitive mammalian hemangioblasts, blood, cardiomyocytes, and blood vessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A role of EphB4 receptor and its ligand, ephrin-B2, in erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphB and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Novel expression gradients of Eph-like receptor tyrosine kinases in the developing chick retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Axonal protein synthesis provides a mechanism for localized regulation at an intermediate target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Tiam1 mediates neurite outgrowth induced by ephrin-B1 and EphA2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

EphA receptor signaling--complexity and emerging themes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Multivalent ligands control stem cell behaviour in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A restricted cell population propagates glioblastoma growth after chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Eph receptors and ephrins as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Emerging strategies for EphA2 receptor targeting for cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

A novel, potent, and specific ephrinA1-based cytotoxin against EphA2 receptor expressing tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Plasticity of cell migration: a multiscale tuning model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Cell-matrix adhesions in 3D

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-014-1633-0

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

21 January 2018

1 reference

12 December 2020

EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas).

1 reference

12 December 2020

Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee

1 reference

12 December 2020

Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling

1 reference

12 December 2020

Up-regulation of ephrin-A1 during melanoma progression

1 reference

12 December 2020

Cooperative interactions of laminin 5 gamma2 chain, matrix metalloproteinase-2, and membrane type-1-matrix/metalloproteinase are required for mimicry of embryonic vasculogenesis by aggressive melanoma.

1 reference

12 December 2020

Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain

1 reference

12 December 2020

Cancer cells exploit the Eph-ephrin system to promote invasion and metastasis: tales of unwitting partners

1 reference

12 December 2020

Ephrin-B2 overexpression enhances integrin-mediated ECM-attachment and migration of B16 melanoma cells.

1 reference

12 December 2020

EphB receptors coordinate migration and proliferation in the intestinal stem cell niche

1 reference

12 December 2020

ADAM12-cleaved ephrin-A1 contributes to lung metastasis

1 reference

12 December 2020

A paradigm shift in EPH receptor interaction: biological relevance of EPHB6 interaction with EPHA2 and EPHB2 in breast carcinoma cell lines.

1 reference

12 December 2020

Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood.

1 reference

12 December 2020

Selective expression of the receptor tyrosine kinase, HTK, on human erythroid progenitor cells

1 reference

12 December 2020

Phosphoinositide 3-kinase regulates membrane Type 1-matrix metalloproteinase (MMP) and MMP-2 activity during melanoma cell vasculogenic mimicry.

1 reference

12 December 2020

Ephrin-A1 is a negative regulator in glioma through down-regulation of EphA2 and FAK.

1 reference

12 December 2020

EPH receptors in cancer.

1 reference

12 December 2020

Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2).

1 reference

12 December 2020

Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients.

1 reference

12 December 2020

EphA2 overexpression causes tumorigenesis of mammary epithelial cells.

1 reference

12 December 2020

Epithelial cell kinase-B61: an autocrine loop modulating intestinal epithelial migration and barrier function

1 reference

12 December 2020

c-Cbl-dependent EphA2 protein degradation is induced by ligand binding.

1 reference

12 December 2020

E-cadherin regulates the function of the EphA2 receptor tyrosine kinase

1 reference

12 December 2020

Expression of Eph receptors and ephrins is differentially regulated by E-cadherin.

1 reference

12 December 2020

Prediction and validation of the distinct dynamics of transient and sustained ERK activation

1 reference

12 December 2020

10.1007/S00018-014-1633-0

Identifiers

DOI

1 reference

31 August 2017

1 reference

PubMed ID

24794629