The interplay between Src family kinases and receptor tyrosine kinases (Q35920901)

11 August 2017

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title

The interplay between Src family kinases and receptor tyrosine kinases (English)

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11 August 2017

Paul A Bromann

1

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11 August 2017

Hasan Korkaya

series ordinal

2

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11 August 2017

Sara A Courtneidge

series ordinal

3

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11 August 2017

language of work or name

English

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publication date

1 October 2004

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11 August 2017

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11 August 2017

23

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11 August 2017

48

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11 August 2017

7957-7968

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208079

11 August 2017

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cites work

Src family tyrosine kinases and growth factor signaling

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7 January 2021

Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The role of c-Src in platelet-derived growth factor alpha receptor internalization

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src promotes destruction of c-Cbl: implications for oncogenic synergy between Src and growth factor receptors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src family kinases and HER2 interactions in human breast cancer cell growth and survival

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Cisplatin-induced activation of the EGF receptor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

c-Src, receptor tyrosine kinases, and human cancer

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Phospholipase Cgamma activates Ras on the Golgi apparatus by means of RasGRP1

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The role of STATs in transcriptional control and their impact on cellular function

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

No requirement for src family kinases for PDGF signaling in fibroblasts expressing SV40 large T antigen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The proto-oncogene c-Cbl is a negative regulator of DNA synthesis initiated by both receptor and cytoplasmic tyrosine kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Co-localization of 125I-epidermal growth factor and ferritin-low density lipoprotein in coated pits: a quantitative electron microscopic study in normal and mutant human fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Requirement of Src kinase Lyn for induction of DNA synthesis by granulocyte colony-stimulating factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Tightly regulated and inducible expression of dominant interfering dynamin mutant in stably transformed HeLa cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Translocation of Src kinase to the cell periphery is mediated by the actin cytoskeleton under the control of the Rho family of small G proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

v-Src's hold over actin and cell adhesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Intracellular Translocation of Iodine-125-Labeled Insulin: Direct Demonstration in Isolated Hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Regulation of mRNA stability in mammalian cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Ubiquitin-mediated degradation of active Src tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Analysing c-kit internalization using a functional c-kit-EGFP chimera containing the fluorochrome within the extracellular domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Membranous intermediates in endocytosis are labile, as shown in a temperature-sensitive mutant

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

c-Src regulation of fibroblast growth factor-induced proliferation in murine embryonic fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Cbl-c suppresses v-Src-induced transformation through ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

STAT5b, a Mediator of Synergism between c-Src and the Epidermal Growth Factor Receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Phosphorylation of protein kinase Cdelta on distinct tyrosine residues regulates specific cellular functions.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Association between the PDGF receptor and members of the src family of tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Identification of Tyr900 in the kinase domain of c-Kit as a Src-dependent phosphorylation site mediating interaction with c-Crk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Platelet-derived growth factor-stimulated migration of murine fibroblasts is associated with epidermal growth factor receptor expression and tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src is required for cell migration and shape changes induced by fibroblast growth factor 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Involvement of pp60c-src with two major signaling pathways in human breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Potentiation of epidermal growth factor receptor-mediated oncogenesis by c-Src: implications for the etiology of multiple human cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src family kinases and nitric oxide production are required for hepatocyte growth factor-stimulated endothelial cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Agrin-induced activation of acetylcholine receptor-bound Src family kinases requires Rapsyn and correlates with acetylcholine receptor clustering.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src-class kinases act within the agrin/MuSK pathway to regulate acetylcholine receptor phosphorylation, cytoskeletal anchoring, and clustering.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Integrin-induced epidermal growth factor (EGF) receptor activation requires c-Src and p130Cas and leads to phosphorylation of specific EGF receptor tyrosines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Role of the basic, proline-rich region of dynamin in Src homology 3 domain binding and endocytosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

PKCdelta acts as a growth and tumor suppressor in rat colonic epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Signaling via Shc family adapter proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Selective effect of nerve growth factor on some Golgi and lysosomal enzyme activities of rat pheochromocytoma (PC12) cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src family kinases negatively regulate platelet-derived growth factor alpha receptor-dependent signaling and disease progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

New roles for Src kinases in control of cell survival and angiogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Ephrin-A1 induces c-Cbl phosphorylation and EphA receptor down-regulation in T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Identification of dynamin, a novel mechanochemical enzyme that mediates interactions between microtubules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src, Fyn, and Yes are not required for neuromuscular synapse formation but are necessary for stabilization of agrin-induced clusters of acetylcholine receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Cellular functions regulated by Src family kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Autophosphorylation activity and association with Src family kinase of Sky receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Critical roles of c-Kit tyrosine residues 567 and 719 in stem cell factor-induced chemotaxis: contribution of src family kinase and PI3-kinase on calcium mobilization and cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

EphB1 recruits c-Src and p52Shc to activate MAPK/ERK and promote chemotaxis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Overexpression of cellular Src in fibroblasts enhances endocytic internalization of epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Activation and translocation of c-Src to the cytoskeleton by both platelet-derived growth factor and epidermal growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Identification of sites on epidermal growth factor receptors which are phosphorylated by pp60src in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208079

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208079

1 reference

11 August 2017

1 reference