Biological significance of the importin-β family-dependent nucleocytoplasmic transport pathways (Q38207085)

31 August 2017

Biological significance of the importin-β family-dependent nucleocytoplasmic transport pathways (English)

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31 August 2017

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766099%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Naoko Imamoto

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766099%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

23 May 2014

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31 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766099%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766099%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

7

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766099%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

727-748

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24766099%20AND%20SRC:MED&resulttype=core&format=json

Nucleocytoplasmic transport: taking an inventory

1 June 2020

cites work

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The nuclear pore complex and nuclear transport

21 January 2018

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Role of the nuclear transport factor p10 in nuclear import.

21 January 2018

1 reference

Hikeshi, a nuclear import carrier for Hsp70s, protects cells from heat shock-induced nuclear damage

21 January 2018

1 reference

Evolutionary and transcriptional analysis of karyopherin beta superfamily proteins

21 January 2018

1 reference

Importin α: a multipurpose nuclear-transport receptor

21 January 2018

1 reference

Rules for nuclear localization sequence recognition by karyopherin beta 2

21 January 2018

1 reference

CRM1-mediated nuclear export: to the pore and beyond.

21 January 2018

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Classical nuclear localization signals: definition, function, and interaction with importin alpha

21 January 2018

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Karyopherin flexibility in nucleocytoplasmic transport

21 January 2018

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Structural biology of nucleocytoplasmic transport

21 January 2018

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Upstream and downstream of ran GTPase

21 January 2018

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Nucleocytoplasmic protein transport and recycling of Ran.

21 January 2018

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Molecular mechanism of the nuclear protein import cycle

21 January 2018

1 reference

Proteomic analysis of the mammalian nuclear pore complex

21 January 2018

1 reference

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

21 January 2018

1 reference

Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death

21 January 2018

1 reference

CCCTC-binding factor controls its own nuclear transport via regulating the expression of importin 13.

21 January 2018

1 reference

Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis

21 January 2018

1 reference

Redox-dependent control of FOXO/DAF-16 by transportin-1.

21 January 2018

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Forkhead box o as a sensor, mediator, and regulator of redox signaling.

21 January 2018

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Involvement of transportin 2-mediated HuR import in muscle cell differentiation

21 January 2018

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The cleavage of HuR interferes with its transportin-2-mediated nuclear import and promotes muscle fiber formation

21 January 2018

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Transportin 2 regulates apoptosis through the RNA-binding protein HuR.

21 January 2018

1 reference

Importin alpha protein acts as a negative regulator for Snail protein nuclear import

21 January 2018

1 reference

Regional distribution of importin subtype mRNA expression in the nervous system: study of early postnatal and adult mouse

21 January 2018

1 reference

Distinct effects of importin α2 and α4 on Oct3/4 localization and expression in mouse embryonic stem cells.

21 January 2018

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Expression of nuclear transport importins beta 1 and beta 3 is regulated during rodent spermatogenesis.

21 January 2018

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Expression of testicular germ cell genes identified by differential display analysis

21 January 2018

1 reference

Cloning and characterization of rat importin 9: implication for its neuronal function.

21 January 2018

1 reference

A novel karyopherin-beta homolog is developmentally and hormonally regulated in fetal lung

21 January 2018

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Importin 13 serves as a potential marker for corneal epithelial progenitor cells

21 January 2018

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Expression and subcellular distribution of imp13 are regulated in brain development

21 January 2018

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Identification of a novel putative Ran-binding protein and its close homologue

21 January 2018

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RANBP17 is localized to the XY body of spermatocytes and interacts with SPEM1 on the manchette of elongating spermatids

21 January 2018

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Cse1l is essential for early embryonic growth and development

21 January 2018

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Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1

21 January 2018

1 reference

Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins

21 January 2018

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Steroidal regulation of uterine miRNAs is associated with modulation of the miRNA biogenesis components Exportin-5 and Dicer1.

21 January 2018

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Differential gene expression during terminal erythroid differentiation

21 January 2018

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Stem cells transform into a cardiac phenotype with remodeling of the nuclear transport machinery

21 January 2018

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Involvement of importin-4 in the transport of transition protein 2 into the spermatid nucleus

21 January 2018

1 reference

Genome-wide profiling of developmental, hormonal or environmental responsiveness of the nucleocytoplasmic transport receptors in Arabidopsis

21 January 2018

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Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni

21 January 2018

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Genes involved in the RNA interference pathway are differentially expressed during sea urchin development.

21 January 2018

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21 January 2018

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Time course of housekeeping gene expression changes in diffuse alveolar damage induced by hyperoxia exposure in mice

21 January 2018

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Age-associated reduction of nuclear protein import in human fibroblasts

21 January 2018

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1,25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells

21 January 2018

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Differentiation-associated alteration in gene expression of importins and exportins in human leukemia HL-60 cells

21 January 2018

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Repression of classical nuclear export by S-nitrosylation of CRM1.

21 January 2018

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Comprehensive identification and modified-site mapping of S-nitrosylated targets in prostate epithelial cells

21 January 2018

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The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export

21 January 2018

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Sumoylation regulates Kap114-mediated nuclear transport

21 January 2018

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Protein phosphatase 1H, overexpressed in colon adenocarcinoma, is associated with CSE1L.

21 January 2018

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PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

21 January 2018

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Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells.

21 January 2018

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NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3

21 January 2018

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A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons

21 January 2018

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Specific binding of the karyopherin Kap121p to a subunit of the nuclear pore complex containing Nup53p, Nup59p, and Nup170p.

21 January 2018

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Cell cycle regulated transport controlled by alterations in the nuclear pore complex.

21 January 2018

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Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p

21 January 2018

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Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1

21 January 2018

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Yeast karyopherin Kap95 is required for cell cycle progression at Start

21 January 2018

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Cell cycle-regulated attachment of the ubiquitin-related protein SUMO to the yeast septins

21 January 2018

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The role of karyopherins in the regulated sumoylation of septins

21 January 2018

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Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells

21 January 2018

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Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication

21 January 2018

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Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformans

21 January 2018

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Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip

21 January 2018

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Modulation of histone deposition by the karyopherin kap114

21 January 2018

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Active maintenance of nuclear actin by importin 9 supports transcription

21 January 2018

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Stage-specific Importin13 activity influences meiosis of germ cells in the mouse.

21 January 2018

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Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast

21 January 2018

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KapI, a non-essential member of the Pse1p/Imp5 karyopherin family, controls colonial and asexual development in Aspergillus nidulans.

21 January 2018

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The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1.

21 January 2018

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Leptomycins A and B, new antifungal antibiotics. II. Structure elucidation

21 January 2018

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Crm1 is a mitotic effector of Ran-GTP in somatic cells

21 January 2018

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Temporal and spatial control of nucleophosmin by the Ran-Crm1 complex in centrosome duplication

21 January 2018

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The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins

21 January 2018

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tRNA actively shuttles between the nucleus and cytosol in yeast

21 January 2018

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Genome-wide investigation of the role of the tRNA nuclear-cytoplasmic trafficking pathway in regulation of the yeast Saccharomyces cerevisiae transcriptome and proteome

21 January 2018

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The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

21 January 2018

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Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p.

21 January 2018

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Msn5p is involved in formaldehyde resistance but not in oxidative stress response in the methylotrophic yeast Candida boidinii.

21 January 2018

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Identification of a nuclear export receptor for tRNA

21 January 2018

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Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA

21 January 2018

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Linking tRNA localization with activation of nutritional stress responses.

21 January 2018

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Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p

21 January 2018

1 reference

Export of importin alpha from the nucleus is mediated by a specific nuclear transport factor

21 January 2018

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Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae

21 January 2018

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Cse1p is involved in export of yeast importin alpha from the nucleus

21 January 2018

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Heat-shock induced nuclear retention and recycling inhibition of importin alpha.

21 January 2018

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Cellular stresses induce the nuclear accumulation of importin alpha and cause a conventional nuclear import block

21 January 2018

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Dissecting the signaling events that impact classical nuclear import and target nuclear transport factors

21 January 2018

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CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae

21 January 2018

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Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast

21 January 2018

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The human CAS protein which is homologous to the CSE1 yeast chromosome segregation gene product is associated with microtubules and mitotic spindle

21 January 2018

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Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells

21 January 2018

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hCAS/CSE1L associates with chromatin and regulates expression of select p53 target genes

21 January 2018

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Cse1l is a negative regulator of CFTR-dependent fluid secretion

21 January 2018

1 reference

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

21 January 2018

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Nuclear export of microRNA precursors

21 January 2018

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Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

21 January 2018

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Global microRNA elevation by inducible Exportin 5 regulates cell cycle entry.

21 January 2018

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A genetic defect in exportin-5 traps precursor microRNAs in the nucleus of cancer cells

21 January 2018

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Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs

21 January 2018

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MIR-137 suppresses growth and invasion, is downregulated in oligodendroglial tumors and targets CSE1L.

21 January 2018

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Identification of ZNF217, hnRNP-K, VEGF-A and IPO7 as targets for microRNAs that are downregulated in prostate carcinoma

21 January 2018

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Perturbing nuclear transport in Drosophila eye imaginal discs causes specific cell adhesion and axon guidance defects.

21 January 2018

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Moleskin is essential for the formation of the myotendinous junction in Drosophila

21 January 2018

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A genetic screen in Drosophila for genes interacting with senseless during neuronal development identifies the importin moleskin

21 January 2018

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Delta and Egfr expression are regulated by Importin-7/Moleskin in Drosophila wing development.

21 January 2018

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smoothened and thickveins regulate Moleskin/Importin 7-mediated MAP kinase signaling in the developing Drosophila eye.

21 January 2018

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The moleskin gene product is essential for Caudal-mediated constitutive antifungal Drosomycin gene expression in Drosophila epithelia

21 January 2018

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Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads

21 January 2018

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Importin-beta11 regulates synaptic phosphorylated mothers against decapentaplegic, and thereby influences synaptic development and function at the Drosophila neuromuscular junction.

21 January 2018

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The nuclear import of Frizzled2-C by Importins-beta11 and alpha2 promotes postsynaptic development

21 January 2018

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Importin 13 regulates neurotransmitter release at the Drosophila neuromuscular junction

21 January 2018

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Nuclear export of actin: a novel mechanism regulating the subcellular localization of a major cytoskeletal protein

21 January 2018

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Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila

21 January 2018

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Rice Importin β1 gene affects pollen tube elongation

21 January 2018

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An Arabidopsis homolog of importin β1 is required for ABA response and drought tolerance

21 January 2018

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Mutation of SAD2, an importin beta-domain protein in Arabidopsis, alters abscisic acid sensitivity.

21 January 2018

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Transportin-SR is required for proper splicing of resistance genes and plant immunity

21 January 2018

1 reference

Exportin1 genes are essential for development and function of the gametophytes in Arabidopsis thaliana.

21 January 2018

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Isolation and characterization of the Arabidopsis heat-intolerant 2 (hit2) mutant reveal the essential role of the nuclear export receptor EXPORTIN1A (XPO1A) in plant heat tolerance

21 January 2018

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PAUSED encodes the Arabidopsis exportin-t ortholog

21 January 2018

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PAUSED, a putative exportin-t, acts pleiotropically in Arabidopsis development but is dispensable for viability

21 January 2018

1 reference

Seizures increase importin-beta1 expression in NG2+ cells in the rat hippocampus

21 January 2018

1 reference

Expanded polyglutamine domain possesses nuclear export activity which modulates subcellular localization and toxicity of polyQ disease protein via exportin-1.

21 January 2018

1 reference

Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease

21 January 2018

1 reference

Influence of heart failure on nucleocytoplasmic transport in human cardiomyocytes

21 January 2018

1 reference

Limb-girdle muscular dystrophy 1F is caused by a microdeletion in the transportin 3 gene.

21 January 2018

1 reference

Next-generation sequencing identifies transportin 3 as the causative gene for LGMD1F

21 January 2018

1 reference

Importin 13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells

21 January 2018

1 reference

Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma

21 January 2018

1 reference

The impact of glucocorticoid polymorphisms on markers of neonatal respiratory disease after antenatal betamethasone administration

21 January 2018

1 reference

2p15-p16.1 microdeletion syndrome: molecular characterization and association of the OTX1 and XPO1 genes with autism spectrum disorders

21 January 2018

1 reference

Expression of cellular apoptosis susceptibility protein in serous ovarian carcinoma: a clinicopathologic and immunohistochemical study

21 January 2018

1 reference

AKT activation drives the nuclear localization of CSE1L and a pro-oncogenic transcriptional activation in ovarian cancer cells.

21 January 2018

1 reference

A new diagnostic algorithm for Burkitt and diffuse large B-cell lymphomas based on the expression of CSE1L and STAT3 and on MYC rearrangement predicts outcome

21 January 2018

1 reference

Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer

21 January 2018

1 reference

Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.

21 January 2018

1 reference

The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.

21 January 2018

1 reference

Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity

21 January 2018

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Decreased expression of XPO4 is associated with poor prognosis in hepatocellular carcinoma

21 January 2018

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Inducing cell proliferation inhibition and apoptosis via silencing Dicer, Drosha, and Exportin 5 in urothelial carcinoma of the bladder

21 January 2018

1 reference

Importin β1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells

21 January 2018

1 reference

Regulation of cell proliferation and migration by keratin19-induced nuclear import of early growth response-1 in breast cancer cells

21 January 2018

1 reference

An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

21 January 2018

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Inhibition of CRM1-mediated nucleocytoplasmic transport: triggering human melanoma cell apoptosis by perturbing multiple cellular pathways

21 January 2018

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Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia

21 January 2018

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Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia

21 January 2018

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Novel selective inhibitors of nuclear export CRM1 antagonists for therapy in mantle cell lymphoma

21 January 2018

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Prognostic impact and targeting of CRM1 in acute myeloid leukemia

21 January 2018

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Genome-wide studies in multiple myeloma identify XPO1/CRM1 as a critical target validated using the selective nuclear export inhibitor KPT-276.

21 January 2018

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Human topoisomerase IIalpha nuclear export is mediated by two CRM-1-dependent nuclear export signals

21 January 2018

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Human multiple myeloma cells are sensitized to topoisomerase II inhibitors by CRM1 inhibition

21 January 2018

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CSE1L/CAS, a microtubule-associated protein, inhibits taxol (paclitaxel)-induced apoptosis but enhances cancer cell apoptosis induced by various chemotherapeutic drugs

21 January 2018

1 reference

CAS Enhances Chemotherapeutic Drug-Induced p53 Accumulation and Apoptosis: Use of CAS for High-Sensitivity Anticancer Drug Screening

21 January 2018

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The cellular apoptosis susceptibility CAS/CSE1L gene protects ovarian cancer cells from death by suppressing RASSF1C.

21 January 2018

1 reference

Identification of cargo proteins specific for the nucleocytoplasmic transport carrier transportin by combination of an in vitro transport system and stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics.

21 January 2018

1 reference

Quantitative proteomics reveals regulation of karyopherin subunit alpha-2 (KPNA2) and its potential novel cargo proteins in nonsmall cell lung cancer

21 January 2018

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Identification of CRM1-dependent Nuclear Export Cargos Using Quantitative Mass Spectrometry

21 January 2018

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Identification of cargo proteins specific for importin-β with importin-α applying a stable isotope labeling by amino acids in cell culture (SILAC)-based in vitro transport system.

21 January 2018

1 reference

Cellular apoptosis susceptibility (chromosome segregation 1-like,CSE1L) gene is a key regulator of apoptosis, migration and invasion in colorectal cancer

21 January 2018

1 reference