Fibrosis--a lethal component of systemic sclerosis (Q38206104)

31 August 2017

Fibrosis--a lethal component of systemic sclerosis (English)

1 reference

31 August 2017

Yuen Yee Ho

1

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31 August 2017

David Lagares

series ordinal

2

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31 August 2017

Andrew M Tager

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3

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31 August 2017

Mohit Kapoor

series ordinal

4

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31 August 2017

language of work or name

English

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publication date

22 April 2014

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Nature Reviews Rheumatology

31 August 2017

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31 August 2017

10

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31 August 2017

390-402

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31 August 2017

7

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https://scigraph.springernature.com/pub.10.1038/nrrheum.2014.53

31 August 2017

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Mortality in systemic sclerosis: lessons learned from population-based and observational cohort studies

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Understanding fibrosis in systemic sclerosis: shifting paradigms, emerging opportunities

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Cellular and molecular aspects of vascular dysfunction in systemic sclerosis

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Diagnosis and classification of systemic sclerosis

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Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta

31 March 2020

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The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma

31 March 2020

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MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

31 March 2020

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miR-150 down-regulation contributes to the constitutive type I collagen overexpression in scleroderma dermal fibroblasts via the induction of integrin β3.

31 March 2020

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Increased expression of lysyl oxidase in skin with scleroderma

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Cutaneous chronic graft-versus-host disease does not have the abnormal endothelial phenotype or vascular rarefaction characteristic of systemic sclerosis

31 March 2020

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Evidence for progressive reduction and loss of telocytes in the dermal cellular network of systemic sclerosis

31 March 2020

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Telocytes in human skin--are they involved in skin regeneration?

31 March 2020

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Telocytes as supporting cells for myocardial tissue organization in developing and adult heart

31 March 2020

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Telocytes and putative stem cells in the lungs: electron microscopy, electron tomography and laser scanning microscopy

31 March 2020

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Molecular subsets in the gene expression signatures of scleroderma skin

31 March 2020

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Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts

31 March 2020

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31 March 2020

12 December 2020

Vascular complications of scleroderma

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Defective vasculogenesis in systemic sclerosis

31 March 2020

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Angiogenesis and vasculopathy in systemic sclerosis: evolving concepts

31 March 2020

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Thrombospondin 1 in hypoxia-conditioned media blocks the growth of human microvascular endothelial cells and is increased in systemic sclerosis tissues

31 March 2020

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In situ expression of cytokines and cellular adhesion molecules in the skin of patients with systemic sclerosis. Their role in early and late disease

31 March 2020

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Up-regulation of class II major histocompatibility complex and intercellular adhesion molecule 1 expression on scleroderma fibroblasts and endothelial cells by interferon-gamma and tumor necrosis factor alpha in the early disease stage

31 March 2020

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Activation of microvascular pericytes in autoimmune Raynaud's phenomenon and systemic sclerosis

31 March 2020

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Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Dendritic cells a double-edge sword in autoimmune responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Dendritic cells and damage-associated molecular patterns: endogenous danger signals linking innate and adaptive immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Dendritic cells: novel players in fibrosis and scleroderma

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Central role of dendritic cells in the regulation and deregulation of immune responses.

31 March 2020

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An update on an immune system that goes awry in systemic sclerosis

31 March 2020

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Activation of Toll-like receptor 3 augments myofibroblast differentiation.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Poly(I:C) drives type I IFN- and TGFβ-mediated inflammation and dermal fibrosis simulating altered gene expression in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Enhanced interleukin-10 production by dendritic cells upon stimulation with Toll-like receptor 4 agonists in systemic sclerosis that is possibly implicated in CCL18 secretion.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Antifibroblast antibodies in systemic sclerosis induce fibroblasts to produce profibrotic chemokines, with partial exploitation of toll-like receptor 4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Lymphocytes in the skin of patients with progressive systemic sclerosis. Quantification, subtyping, and clinical correlations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Increase in activated T cells and reduction in suppressor inducer T cells in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Involvement of mast cells in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Stimulation of collagen and glycosaminoglycan production in cultured human adult dermal fibroblasts by recombinant human interleukin 6.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Fibrotic disease and the T(H)1/T(H)2 paradigm

31 March 2020

1 reference

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Regulatory effect of extracellular signal-regulated kinases (ERK) on type I collagen synthesis in human dermal fibroblasts stimulated by IL-4 and IL-13.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Interleukin-13 stimulates the transcription of the human alpha2(I) collagen gene in human dermal fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autoimmune mechanisms of scleroderma and a role of oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Interleukin-4- and interleukin-13-enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Human recombinant interleukin-4 induces proliferation and interleukin-6 production by cultured human skin fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

IL-4-induced oxidative stress upregulates VCAM-1 gene expression in human endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Production of type 2 cytokines by CD8+ lung cells is associated with greater decline in pulmonary function in patients with systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Interleukin-13 in systemic sclerosis: relationship to nailfold capillaroscopy abnormalities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Role of IL-13 in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Effector CD8+ T cells in systemic sclerosis patients produce abnormally high levels of interleukin-13 associated with increased skin fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Interleukin-6 signaling drives fibrosis in unresolved inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

IL-6 modulates alpha-smooth muscle actin expression in dermal fibroblasts from IL-6-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Outcomes of patients with systemic sclerosis-associated polyarthritis and myopathy treated with tocilizumab or abatacept: a EUSTAR observational study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Targeting interleukin-6 in rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autoantibodies in systemic sclerosis and fibrosing syndromes: clinical indications and relevance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Clinical significance of anti-topoisomerase I antibody levels determined by ELISA in systemic sclerosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Antifibroblast antibodies from systemic sclerosis patients are internalized by fibroblasts via a caveolin-linked pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autoantibodies to fibrillin 1 in systemic sclerosis: ethnic differences in antigen recognition and lack of correlation with specific clinical features or HLA alleles

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autoantibody against matrix metalloproteinase-3 in patients with systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Endoplasmic reticulum stress as a pro-fibrotic stimulus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

The unfolded protein response in secretory cell function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autophagy eliminates a specific species of misfolded procollagen and plays a protective role in cell survival against ER stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Scleroderma-like properties of skin from caveolin-1-deficient mice: implications for new treatment strategies in patients with fibrosis and systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Heat-shock protein 90, a chaperone for folding and regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Critical regulation of TGFbeta signaling by Hsp90

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

The Hsp90 inhibitor 17-AAG represses calcium-induced cytokeratin 1 and 10 expression in HaCaT keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Heat shock protein 90 inhibitor attenuates renal fibrosis through degradation of transforming growth factor-β type II receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Decreased susceptibility to Fas-induced apoptosis of systemic sclerosis dermal fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Alpha-smooth muscle actin is crucial for focal adhesion maturation in myofibroblasts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen-producing cells in systemic sclerosis fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Normal skin wound and hypertrophic scar myofibroblasts have differential responses to apoptotic inductors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

An essential role for resident fibroblasts in experimental lung fibrosis is defined by lineage-specific deletion of high-affinity type II transforming growth factor β receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

TGF-β signaling in fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Recombinant human anti–transforming growth factor β1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

LPA1 receptor activation promotes renal interstitial fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

LPA1-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Lipids and eicosanoids in fibrosis: emerging targets for therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Lysoglycerophospholipids in chronic inflammatory disorders: the PLA(2)/LPC and ATX/LPA axes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Insights into the pharmacological relevance of lysophospholipid receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Production of lysophosphatidic acid in blister fluid: involvement of a lysophospholipase D activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Elevated serum levels of arachidonoyl-lysophosphatidic acid and sphingosine 1-phosphate in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Peroxisome proliferator-activated receptor-gamma abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Tumor suppressor and anti-inflammatory actions of PPARgamma agonists are mediated via upregulation of PTEN.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Loss of peroxisome proliferator-activated receptor gamma in mouse fibroblasts results in increased susceptibility to bleomycin-induced skin fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Inhibition of Notch signaling by a γ-secretase inhibitor attenuates hepatic fibrosis in rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Inhibition of Notch signaling prevents experimental fibrosis and induces regression of established fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Wnt/β-catenin signaling is hyperactivated in systemic sclerosis and induces Smad-dependent fibrotic responses in mesenchymal cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Canonical Wnt signaling induces skin fibrosis and subcutaneous lipoatrophy: a novel mouse model for scleroderma?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Thiazolidinediones downregulate Wnt/beta-catenin signaling via multiple mechanisms in breast cancer cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Calcification inhibitors and Wnt signaling proteins are implicated in bovine artery smooth muscle cell calcification in the presence of phosphate and vitamin D sterols

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Surface morphology and mechanical properties of fibroblasts from scleroderma patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Biomechanical regulation of mesenchymal cell function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cell

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

The rationale for targeting the LOX family in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Transmembrane crosstalk between the extracellular matrix--cytoskeleton crosstalk

31 March 2020

1 reference

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Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.

31 March 2020

1 reference

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Therapeutic potential and limitations of new FAK inhibitors in the treatment of cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Relaxin regulates myofibroblast contractility and protects against lung fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Fasudil, a Rho-kinase inhibitor, attenuates bleomycin-induced pulmonary fibrosis in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Fasudil attenuates myocardial fibrosis in association with inhibition of monocyte/macrophage infiltration in the heart of DOCA/salt hypertensive rats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Role of YAP/TAZ in mechanotransduction

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Targeted therapies for systemic sclerosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2014.53

Autotaxin and lysophospholipids in rheumatoid arthritis.

31 March 2020

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12 December 2020

Analysis of gene expression patterns in systemic sclerosis fibroblasts using RNA arbitrarily primed-polymerase chain reaction for differential display.

1 reference

12 December 2020

Elevated serum levels of interleukin 4 (IL-4), IL-10, and IL-13 in patients with systemic sclerosis

1 reference

12 December 2020

Serum levels of interleukin 6 (IL-6), oncostatin M, soluble IL-6 receptor, and soluble gp130 in patients with systemic sclerosis

1 reference

12 December 2020

Functional impairment of systemic scleroderma patients with digital ulcerations: results from the DUO Registry

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12 December 2020

A role for lysophosphatidic acid and sphingosine 1-phosphate in the pathogenesis of systemic sclerosis.

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12 December 2020

Immunological basis of systemic sclerosis

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12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2014.53

1 reference

Dimensions Publication ID

31 August 2017

0 references

1 reference