Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition (Q38204222)

31 August 2017

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition (English)

1 reference

31 August 2017

1 reference

7

1 reference

31 August 2017

6

L Galluzzi

0 references

Guido Kroemer

5

object named as

G Kroemer

0 references

Oliver Kepp

4

object named as

O Kepp

0 references

Christos Chinopoulos

object named as

C Chinopoulos

3

0 references

author name string

M Bonora

1

1 reference

31 August 2017

M R Wieckowski

2

1 reference

31 August 2017

language of work or name

English

0 references

publication date

14 April 2014

1 reference

31 August 2017

1 reference

31 August 2017

34

1 reference

31 August 2017

1475-1486

1 reference

31 August 2017

12

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2014.96

31 August 2017

0 references

cites work

Mitochondrial membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The permeability transition pore complex in cancer cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondria and the autophagy-inflammation-cell death axis in organismal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Molecular mechanisms of necroptosis: an ordered cellular explosion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

ATP synthesis and storage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondria: master regulators of danger signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondria and cell death: outer membrane permeabilization and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Different mitochondrial intermembrane space proteins are released during apoptosis in a manner that is coordinately initiated but can vary in duration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Apoptosis: controlled demolition at the cellular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

S-Nitrosylation of mitochondrial caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

XIAP discriminates between type I and type II FAS-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bax regulates primary necrosis through mitochondrial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Pharmacologic targeting or genetic deletion of mitochondrial cyclophilin D protects from NSAID-induced small intestinal ulceration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Molecular mechanisms of cisplatin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Targeting Bax interaction sites reveals that only homo-oligomerization sites are essential for its activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial membrane permeabilization in neuronal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Targeting mitochondria for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondria as therapeutic targets for cancer chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Inhibition of the Mitochondrial Permeability Transition for Cytoprotection: Direct versus Indirect Mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cell death assays for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Individuality: the barrier to optimal immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The apoptotic pore on mitochondria: are we breaking through or still stuck?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The mitochondrial megachannel is the permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The mitochondrial permeability transition pore may comprise VDAC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cyclophilin-D binds strongly to complexes of the voltage-dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Inhibition of Ca2(+)-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adeni

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

A fourth ADP/ATP carrier isoform in man: identification, bacterial expression, functional characterization and tissue distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Adenine nucleotide translocase 3 (ANT3) overexpression induces apoptosis in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

VDAC2 inhibits BAK activation and mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The mitochondrial transporter family (SLC25): physiological and pathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Permeability transition in rat liver mitochondria is modulated by the ATP-Mg/Pi carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca(2+) buffering

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Viral control of mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The mitochondrial phosphate carrier interacts with cyclophilin D and may play a key role in the permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The reversible antiport-uniport conversion of the phosphate carrier from yeast mitochondria depends on the presence of a single cysteine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial benzodiazepine receptors regulate steroid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Peripheral-type benzodiazepine receptor ligands: mitochondrial permeability transition induction in rat cardiac tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The nitric oxide donor sodium nitroprusside requires the 18 kDa Translocator Protein to induce cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Modulation of intracellular Ca2+ signalling in HeLa cells by the apoptotic cell death enhancer PK11195.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Inhibition of the mitochondrial permeability transition by creatine kinase substrates. Requirement for microcompartmentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Regulation of hexokinase binding to VDAC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Hexokinase II: the integration of energy metabolism and control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Disruption of the hexokinase-VDAC complex for tumor therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Methyl jasmonate binds to and detaches mitochondria-bound hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Voltage-dependent anion channel 1-based peptides interact with hexokinase to prevent its anti-apoptotic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Disruption of hexokinase II-mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Metabolic targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Glucose phosphorylation and mitochondrial binding are required for the protective effects of hexokinases I and II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Hexokinase 1 blocks apoptotic signals at the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Protein kinase Cepsilon interacts with and inhibits the permeability transition pore in cardiac mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Glycogen synthase kinase 3 inhibition slows mitochondrial adenine nucleotide transport and regulates voltage-dependent anion channel phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Chemotherapeutic induction of mitochondrial oxidative stress activates GSK-3α/β and Bax, leading to permeability transition pore opening and tumor cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Local delivery of PKCepsilon-activating peptide mimics ischemic preconditioning in aged hearts through GSK-3beta but not F1-ATPase inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Role of glycogen synthase kinase-3beta in cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bid acts on the permeability transition pore complex to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bad targets the permeability transition pore independent of Bax or Bak to switch between Ca2+-dependent cell survival and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mediation of the antiapoptotic activity of Bcl-xL protein upon interaction with VDAC1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The C-terminal helix of Bcl-x(L) mediates Bax retrotranslocation from the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

p53 opens the mitochondrial permeability transition pore to trigger necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Senescence and aging: the critical roles of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FONC.2014.96

21 January 2018

12 December 2020

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The endoplasmic reticulum-mitochondria connection: one touch, multiple functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Calcium signaling around Mitochondria Associated Membranes (MAMs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial Ca(2+) and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

PML regulates apoptosis at endoplasmic reticulum by modulating calcium release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

ATP synthase--a marvellous rotary engine of the cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The structure and function of mitochondrial F1F0-ATP synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Rotation and structure of FoF1-ATP synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Structure of the mitochondrial ATP synthase by electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial ATP synthase: architecture, function and pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The proton pore in the Escherichia coli F0F1-ATPase: substitution of glutamate by glutamine at position 219 of the alpha-subunit prevents F0-mediated proton permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Each yeast mitochondrial F1F0-ATP synthase complex contains a single copy of subunit 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Direct observation of the rotation of F1-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Essentials for ATP synthesis by F1F0 ATP synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

F1-ATPase is a highly efficient molecular motor that rotates with discrete 120 degree steps.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

An alternative reaction pathway of F1-ATPase suggested by rotation without 80 degrees/40 degrees substeps of a sluggish mutant at low ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Stepping rotation of F(1)-ATPase with one, two, or three altered catalytic sites that bind ATP only slowly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Basic properties of rotary dynamics of the molecular motor Enterococcus hirae V1-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Rotation mechanism of Enterococcus hirae V1-ATPase based on asymmetric crystal structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The peripheral stalk of the mitochondrial ATP synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Sequence and organization of the human mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Assembly and oligomerization of human ATP synthase lacking mitochondrial subunits a and A6L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

ATP synthase from Saccharomyces cerevisiae: location of the OSCP subunit in the peripheral stalk region

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial ATP synthase deficiency due to a mutation in the ATP5E gene for the F1 epsilon subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Yeast mitochondrial F1F0-ATP synthase exists as a dimer: identification of three dimer-specific subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

ATP synthase oligomerization: from the enzyme models to the mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Characterization of domain interfaces in monomeric and dimeric ATP synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Dimer ribbons of ATP synthase shape the inner mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Formation of the yeast F1F0-ATP synthase dimeric complex does not require the ATPase inhibitor protein, Inh1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The GxxxG motif of the transmembrane domain of subunit e is involved in the dimerization/oligomerization of the yeast ATP synthase complex in the mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Structure of dimeric mitochondrial ATP synthase: novel F0 bridging features and the structural basis of mitochondrial cristae biogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Regulation of mitochondrial structure and function by the F1Fo-ATPase inhibitor protein, IF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

IF(1): setting the pace of the F(1)F(o)-ATP synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The inhibitor protein (IF1) promotes dimerization of the mitochondrial F1F0-ATP synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Regulatory mechanisms of proton-translocating F(O)F (1)-ATP synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

How the regulatory protein, IF1, inhibits F1-ATPase from bovine mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Molecular Regulation of the Mitochondrial F(1)F(o)-ATPsynthase: Physiological and Pathological Significance of the Inhibitory Factor 1 (IF(1)).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Modeling of ATP-ADP steady-state exchange rate mediated by the adenine nucleotide translocase in isolated mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial consumption of cytosolic ATP: not so fast.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The "B space" of mitochondrial phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial dynamics and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Role of Bax and Bak in mitochondrial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Modulation of the mitochondrial permeability transition by cyclophilin D: moving closer to F(0)-F(1) ATP synthase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mg2+-Induced ADP-dependent inhibition of the ATPase activity of beef heart mitochondrial coupling factor F1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

An inhibitory high affinity binding site for ADP in the oligomycin-sensitive ATPase of beef heart submitochondrial particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The pre-steady state and steady-state kinetics of the ATPase activity of mitochondrial F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Interaction of Mg2+ with F0.F1 mitochondrial ATPase as related to its slow active/inactive transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Active/inactive state transitions of mitochondrial ATPase molecules influenced by Mg2+ , anions and aurovertin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Redox regulation of mitochondrial ATP synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

On the voltage dependence of the mitochondrial permeability transition pore. A critical appraisal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Energy metabolism during apoptosis. Bcl-2 promotes survival in hematopoietic cells induced to apoptose by growth factor withdrawal by stabilizing a form of metabolic arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Respiratory active mitochondrial supercomplexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Is supercomplex organization of the respiratory chain required for optimal electron transfer activity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Cyclophilin D modulates mitochondrial F0F1-ATP synthase by interacting with the lateral stalk of the complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Oligomycin frames a common drug-binding site in the ATP synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines : a mechanism for induction of apoptosis via the 18 kDa mitochondrial tran

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Dimers of mitochondrial ATP synthase form the permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

What Makes You Can Also Break You, Part II: Mitochondrial Permeability Transition Pore Formation by Dimers of the F1FO ATP-Synthase?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Induction of the permeability transition pore in cells depleted of mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The transmembrane domain of subunit b of the Escherichia coli F1F(O) ATP synthase is sufficient for H(+)-translocating activity together with subunits a and c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

A 0.1-700 Hz current through a voltage-clamped pore: candidate protein for initiator of neural oscillations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Ion pores made of mitochondrial ATP synthase subunit c in the neuronal plasma membrane and Batten disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Phosphorylation of a peptide related to subunit c of the F0F1-ATPase/ATP synthase and relationship to permeability transition pore opening in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Effect of peripheral benzodiazepine receptor (PBR/TSPO) ligands on opening of Ca2+-induced pore and phosphorylation of 3.5-kDa polypeptide in rat brain mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Potential role of subunit c of F0F1-ATPase and subunit c of storage body in the mitochondrial permeability transition. Effect of the phosphorylation status of subunit c on pore opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

What is the mitochondrial permeability transition pore?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

No death without life: vital functions of apoptotic effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Non-apoptotic functions of apoptosis-regulatory proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The mitochondrial permeability transition pore may comprise VDAC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Involvement of Cyclophilin D in the Activation of A mitochondrial Pore by Ca2+ and Oxidant Stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial apoptosis without VDAC

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Osmotic reversal of phosphate-induced mitochondrial swelling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Unexpected role of the phosphate carrier in mitochondrial fragmentation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

PK11195, a specific ligand of the peripheral benzodiazepine receptor, may protect pancreatic beta-cells from cytokine-induced cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Modulation of the mitochondrial permeability transition pore complex in GSK-3beta-mediated myocardial protection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Studies on the activation of purified mitochondrial ATPase by phospholipids

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Mitochondrial diaphorases as NAD⁺ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Tightly bound adenosine diphosphate, which inhibits the activity of mitochondrial F1-ATPase, is located at the catalytic site of the enzyme

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Energy-dependent transformation of the catalytic activities of the mitochondrial F0 x F1-ATP synthase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The role of inorganic phosphate in the release of Ca2+ from rat-liver mitochondria

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

The effect of inorganic pyrophosphate on the activity and Pi-binding properties of mitochondrial F1-ATPase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Structural organization of mitochondrial ATP synthase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Oxidative stress, thiol reagents, and membrane potential modulate the mitochondrial permeability transition by affecting nucleotide binding to the adenine nucleotide translocase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.96

Protoporphyrin IX, an endogenous ligand of the peripheral benzodiazepine receptor, potentiates induction of the mitochondrial permeability transition and the killing of cultured hepatocytes by rotenone.

31 March 2020

1 reference

12 December 2020

Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine

1 reference

12 December 2020

Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo.

1 reference

12 December 2020

The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms

1 reference

12 December 2020

Modulation of the mitochondrial megachannel by divalent cations and protons

1 reference

12 December 2020

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization

1 reference

12 December 2020

The mitochondrial permeability transition pore may comprise VDAC molecules. I. Binary structure and voltage dependence of the pore

1 reference

12 December 2020

Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress

1 reference

12 December 2020

Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore. II. The minimal requirements for pore induction underscore a key role for transmembrane electrical potential, matrix pH, and matrix Ca2+.

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.96

1 reference

Dimensions Publication ID

31 August 2017

0 references

1 reference