Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition (Q33640002)

28 July 2017

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition (English)

1 reference

28 July 2017

Andrea Rasola

1

1 reference

28 July 2017

Marco Sciacovelli

2

1 reference

28 July 2017

Federica Chiara

3

1 reference

28 July 2017

Boris Pantic

4

1 reference

28 July 2017

William S Brusilow

5

1 reference

28 July 2017

Paolo Bernardi

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

22 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

1 reference

28 July 2017

107

1 reference

28 July 2017

2

1 reference

28 July 2017

726-731

1 reference

Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

A mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

MAP kinase signalling pathways in cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

MAPKs: function, regulation, role in cancer and therapeutic targeting

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Rewired ERK-JNK signaling pathways in melanoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Hyperactive Ras in developmental disorders and cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial permeability transition from in vitro artifact to disease target

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Signal transduction in prostate cancer progression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Oxidative neuronal injury. The dark side of ERK1/2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The glamour and gloom of glycogen synthase kinase-3

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Mitogen-activated protein kinase/extracellular signal-regulated kinase attenuates 3-hydroxykynurenine-induced neuronal cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation By electron flow through the respiratory chain complex i.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Mitochondrial extracellular signal-regulated kinases 1/2 (ERK1/2) are modulated during brain development.

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Aggravation of necrotic death of glucose-deprived cells by the MEK1 inhibitors U0126 and PD184161 through depletion of ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

A flow cytometry assay simultaneously detects independent apoptotic parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)- and PKB/AKT-independent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Modulation of the mitochondrial permeability transition pore complex in GSK-3beta-mediated myocardial protection

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080742

12 December 2020

inferred from PubMed ID database lookup

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080742

12 December 2020

inferred from PubMed ID database lookup

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080742

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0912742107

1 reference

release_w4rkm66gqjdj7nti42f2eq3hd4

28 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w4rkm66gqjdj7nti42f2eq3hd4

24 November 2022

mapped directly with Wikidata item

PMCID

2818893

1 reference

28 July 2017

1 reference