Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy. (Q38165627)

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1 March 2020

title

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy (English)

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1 March 2020

2

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1 March 2020

Danuta S Kalinowski

4

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Des R. Richardson

8

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1 March 2020

Darius Lane

6

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Sumit Sahni

7

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5

Patric J Jansson

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1 March 2020

author name string

Bernard A Fang

1

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Kyung Chan Park

3

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1 March 2020

language of work or name

English

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publication date

21 November 2013

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Biochimica et Biophysica Acta

1 March 2020

published in

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1 March 2020

volume

1845

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1 March 2020

page(s)

1-19

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issue

1

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The Chemistry Development Kit (CDK): an open-source Java library for Chemo- and Bioinformatics

1 March 2020

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5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Copper(II) binding to Cap43 protein fragments

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Increased N-myc downstream-regulated gene 1 expression is associated with breast atypia-to-carcinoma progression.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Hypophosphorylation of Mdm2 augments p53 stability

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

WoLF PSORT: protein localization predictor

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

SGK1 activity in Na+ absorbing airway epithelial cells monitored by assaying NDRG1-Thr346/356/366 phosphorylation.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Nickel (Ni2+) enhancement of alpha-tubulin acetylation in cultured 3T3 cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-Myc down-regulated gene 1 mediates proliferation, invasion, and apoptosis of hepatocellular carcinoma cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Modulation of differentiation-related gene 1 expression by cell cycle blocker mimosine, revealed by proteomic analysis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Nickel(II) binding to Cap43 protein fragments.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Cathepsin B as a cancer target

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Geno3D: automatic comparative molecular modelling of protein.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Inflammation, proteases and cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Identification and classification of p53-regulated genes

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Preclinical and clinical studies of novel breast cancer drugs targeting molecules involved in protein kinase C signaling, the putative metastasis-suppressor gene Cap43 and the Y-box binding protein-1.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

NDRG1 is necessary for p53-dependent apoptosis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Molecular chaperones and the regulation of neurotransmitter exocytosis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The medicinal chemistry of novel iron chelators for the treatment of cancer.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Microarray analysis of normal cervix, carcinoma in situ, and invasive cervical cancer: identification of candidate genes in pathogenesis of invasion in cervical cancer.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Advancing a clinically relevant perspective of the clonal nature of cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Nitric oxide donor, (+/-)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1alpha by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

PRSS3/mesotrypsin is a therapeutic target for metastatic prostate cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Decreased expression of NDRG1 is correlated with tumor progression and poor prognosis in patients with esophageal squamous cell carcinoma.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Nickel-induced transformation shifts the balance between HIF-1 and p53 transcription factors

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Expression of NDRG1, a differentiation-related gene, in human tissues

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Novel chelators for cancer treatment: where are we now?

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The Rho/ROCK pathway for lysophosphatidic acid-induced proteolytic enzyme expression and ovarian cancer cell invasion.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

An NMR study on nickel binding sites in Cap43 protein fragments

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The metastasis suppressor, N-myc downstream regulated gene 1 (NDRG1), upregulates p21 via p53-independent mechanisms.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

NDRG1/Cap43 overexpression in tumor tissues and serum from lung cancer patients.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Inflammation and cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Localization of N-myc downstream-regulated gene 1 in gastric cancer tissue

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Homocysteine-respondent genes in vascular endothelial cells identified by differential display analysis. GRP78/BiP and novel genes

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Mutation screening of the N-myc downstream-regulated gene 1 (NDRG1) in patients with Charcot-Marie-Tooth Disease

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Initiation of human colon cancer cell proliferation by trypsin acting at protease-activated receptor-2

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

NDRG1 is down-regulated in the early apoptotic event induced by camptothecin analogs: the potential role in proteolytic activation of PKC delta and apoptosis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Differential expression patterns of NDRG family proteins in the central nervous system

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Role of Ca(2+) in the regulation of nickel-inducible Cap43 gene expression

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Novel second-generation di-2-pyridylketone thiosemicarbazones show synergism with standard chemotherapeutics and demonstrate potent activity against lung cancer xenografts after oral and intravenous administration in vivo.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Identification of a stress-induced protein during human trophoblast differentiation by differential display analysis.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Preclinical studies of molecular-targeting diagnostic and therapeutic strategies against breast cancer.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream-regulated gene 1/Cap43 may function as tumor suppressor in endometrial cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Molecular pathways to prostate cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Dinitrosyliron complexes are the most abundant nitric oxide-derived cellular adduct: biological parameters of assembly and disappearance.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

TGFbeta modulates PTEN expression independently of SMAD signaling for growth proliferation in colon cancer cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

PI3K/PTEN signaling in angiogenesis and tumorigenesis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Prostate cancer and inflammation: the evidence

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Hypoxia increases cytoplasmic expression of NDRG1, but is insufficient for its membrane localization in human hepatocellular carcinoma

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Inflammation and prostate carcinogenesis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Transmembrane helices predicted at 95% accuracy

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Tumor heterogeneity and personalized medicine

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Actin structure and function.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

PTEN and the PI3-kinase pathway in cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Downregulation of NDRG1 promotes invasion of human gastric cancer AGS cells through MMP-2.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Bp44mT: an orally active iron chelator of the thiosemicarbazone class with potent anti-tumour efficacy

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream-regulated gene 1 is involved in the regulation of cystogenesis in transgenic mice overexpressing human PKD2 gene.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

NPS@: network protein sequence analysis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Gene mapping in Gypsies identifies a novel demyelinating neuropathy on chromosome 8q24

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The TGF-beta, PI3K/Akt and PTEN pathways: established and proposed biochemical integration in prostate cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

A deletion in the N-myc downstream regulated gene 1 (NDRG1) gene in Greyhounds with polyneuropathy

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Nuclear expression of N-myc downstream regulated gene 1/Ca(2+)-associated protein 43 is closely correlated with tumor angiogenesis and poor survival in patients with gastric cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Biomolecules in the computer: Jmol to the rescue

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Regulation of the differentiation-related gene Drg-1 during mouse skin carcinogenesis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1).

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Mesotrypsin promotes malignant growth of breast cancer cells through shedding of CD109

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Enhanced overexpression of an HIF-1/hypoxia-related protein in cancer cells.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

N-myc downstream regulated gene-1/Cap43 may play an important role in malignant progression of prostate cancer, in its close association with E-cadherin.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Association of NDRG1 gene promoter methylation with reduced NDRG1 expression in gastric cancer cells and tissue specimens

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Genomic targets of the human c-Myc protein

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Inflammation and cancer: how hot is the link?

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Chelators at the cancer coalface: desferrioxamine to Triapine and beyond.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

PRSS3 promotes tumour growth and metastasis of human pancreatic cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Improved performance in protein secondary structure prediction by inhomogeneous score combination.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Determination of the DNA sequence recognized by the bHLH-zip domain of the N-Myc protein

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Expression of gelatinase A, tissue inhibitor of metalloproteinases-2, matrilysin, and trypsin(ogen) in lung neoplasms: an immunohistochemical study

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Trypsins and their role in carcinoma growth

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Tumour evolution inferred by single-cell sequencing

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The evolution of iron chelators for the treatment of iron overload disease and cancer.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Crystal Structure of the Human N-Myc Downstream-regulated Gene 2 Protein Provides Insight into Its Role as a Tumor Suppressor

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Down-regulation of NDRG1 promotes migration of cancer cells during reoxygenation

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

A Gly98Val mutation in the N-Myc downstream regulated gene 1 (NDRG1) in Alaskan Malamutes with polyneuropathy

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Gene expression correlates of clinical prostate cancer behavior

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Prognostic significance of NDRG1 expression in oral and oropharyngeal squamous cell carcinoma.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Overexpression of Cap43 gene in supraglottic laryngeal squamous cell carcinoma

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states

1 reference

5 April 2022

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Novel agents and new therapeutics in castration-resistant prostate cancer

1 reference

5 April 2022

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NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Mutational Analysis of thePTENGene in Endometrial Carcinoma and Hyperplasia

1 reference

5 April 2022

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ExPASy: SIB bioinformatics resource portal

1 reference

5 April 2022

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The N-Myc down regulated Gene1 (NDRG1) Is a Rab4a effector involved in vesicular recycling of E-cadherin

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Proteomics identified nuclear N-myc downstream-regulated gene 1 as a prognostic tissue biomarker candidate in renal cell carcinoma.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

1 reference

5 April 2022

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The multiple roles of PTEN in tumor suppression

1 reference

5 April 2022

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Impaired mast cell maturation and degranulation and attenuated allergic responses in Ndrg1-deficient mice

1 reference

5 April 2022

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Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Phosphorylation of RTP, an ER stress-responsive cytoplasmic protein

1 reference

5 April 2022

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Pancreatic trypsinogen and cathepsin B in human pancreatic carcinomas and associated metastatic lesions

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Expression of trypsin in human cancer cell lines and cancer tissues and its tight binding to soluble form of Alzheimer amyloid precursor protein in culture.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Phospholipid species act as modulators in p97/p47-mediated fusion of Golgi membranes

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Hereditary motor and sensory neuropathy associated with auditory neuropathy in a Gypsy family.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Cellular Distribution of NDRG1 Protein in the Rat Kidney and Brain During Normal Postnatal Development

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Molecular portraits and the family tree of cancer

1 reference

5 April 2022

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Identification of high-risk stage II colorectal tumors by combined analysis of the NDRG1 gene expression and the depth of tumor invasion.

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The iron chelator, deferasirox, as a novel strategy for cancer treatment: oral activity against human lung tumor xenografts and molecular mechanism of action

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Metastasis suppressors genes in cancer.

1 reference

5 April 2022

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Enhanced expression of a novel protein in human cancer cells: a potential aid to cancer diagnosis

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Hypoxia in cancer: significance and impact on clinical outcome

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

The myc oncogene: MarvelouslY Complex

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Differential expression of the RTP/Drg1/Ndr1 gene product in proliferating and growth arrested cells

1 reference

5 April 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BBCAN.2013.11.002

Identifiers

DOI

10.1016/J.BBCAN.2013.11.002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24269900%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference