T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells (Q34107166)

31 July 2017

T-box 2 represses NDRG1 through an EGR1-dependent mechanism to drive the proliferation of breast cancer cells (English)

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31 July 2017

K L Redmond

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31 July 2017

N T Crawford

2

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31 July 2017

H Farmer

3

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31 July 2017

Z C D'Costa

4

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31 July 2017

G J O'Brien

5

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31 July 2017

N E Buckley

6

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31 July 2017

R D Kennedy

7

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31 July 2017

P G Johnston

8

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31 July 2017

D P Harkin

9

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P B Mullan

10

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31 July 2017

language of work or name

English

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publication date

29 March 2010

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29

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22

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3252-3262

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https://scigraph.springernature.com/pub.10.1038/onc.2010.84

31 July 2017

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cites work

Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43

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https://api.crossref.org/works/10.1038%2FONC.2010.84

BRCA1 regulates IFN-gamma signaling through a mechanism involving the type I IFNs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

p53 and Egr-1 additively suppress transformed growth in HT1080 cells but Egr-1 counteracts p53-dependent apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Expression of TBX2 promotes anchorage-independent growth and survival in the p53-negative SW13 adrenocortical carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

BRCA1 and c-Myc associate to transcriptionally repress psoriasin, a DNA damage-inducible gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Transcriptional responses to estrogen and progesterone in mammary gland identify networks regulating p53 activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.84

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.84

BRCA1 and GADD45 mediated G2/M cell cycle arrest in response to antimicrotubule agents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Early growth response gene 1 (EGR1) is deleted in estrogen receptor-negative human breast carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2010.84

NDRG1 is necessary for p53-dependent apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

A network of p73, p53 and Egr1 is required for efficient apoptosis in tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

EGR-1 forms a complex with YAP-1 and upregulates Bax expression in irradiated prostate carcinoma cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.84

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.84

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Dimensions Publication ID

31 July 2017

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