Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620. (Q39616078)

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18 January 2020

title

Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620 (English)

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18 January 2020

main subject

gene silencing

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metastatic colon cancer

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1

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18 January 2020

author name string

Hong Chen

series ordinal

2

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18 January 2020

publication date

24 December 2010

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Clinical & Experimental Metastasis

18 January 2020

published in

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volume

28

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18 January 2020

page(s)

127-135

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18 January 2020

issue

2

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https://scigraph.springernature.com/pub.10.1007/s10585-010-9366-4

18 January 2020

exact match

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cites work

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Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint

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NDRG1 is necessary for p53-dependent apoptosis

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Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells

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Egr-1 mediates hypoxia-inducible transcription of the NDRG1 gene through an overlapping Egr-1/Sp1 binding site in the promoter

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N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant.

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Human differentiation-related gene NDRG1 is a Myc downstream-regulated gene that is repressed by Myc on the core promoter region

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Validation of a model of colon cancer progression.

21 January 2018

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Amino acid deprivation induces the transcription rate of the human asparagine synthetase gene through a timed program of expression and promoter binding of nutrient-responsive basic region/leucine zipper transcription factors as well as localized hi

21 January 2018

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A novel molecular marker for early detection and evaluating prognosis of gastric cancer: N-myc downstream regulated gene-1 (NDRG1).

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Gene expression profiling of primary and metastatic colon cancers identifies a reduced proliferative rate in metastatic tumors.

21 January 2018

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Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells

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Functions of site-specific histone acetylation and deacetylation

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High-resolution profiling of histone methylations in the human genome

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Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation

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Regulation of chromatin structure by histone H3S10 phosphorylation

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Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer

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12 December 2020

Classification of human colorectal adenocarcinoma cell lines

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12 December 2020

Hyperinducibility of hypoxia-responsive genes without p53/p21-dependent checkpoint in aggressive prostate cancer

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12 December 2020

Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage

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12 December 2020

10.1007/S10585-010-9366-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21184144%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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