Canonical RTK-Ras-ERK signaling and related alternative pathways (Q38125960)

13 October 2017

Canonical RTK-Ras-ERK signaling and related alternative pathways (English)

1 reference

13 October 2017

1

1 reference

13 October 2017

Meera V Sundaram

1

1 reference

29 August 2017

11 July 2013

1 reference

13 October 2017

1 reference

13 October 2017

1-38

1 reference

Alternative splicing affecting a novel domain in the C. elegans EGL-15 FGF receptor confers functional specificity

13 October 2017

1 reference

12 December 2020

Dynamic Interplay of the SUMO and ERK Pathways in Regulating Elk-1 Transcriptional Activity

1 reference

12 December 2020

Modulation of EGF receptor-mediated vulva development by the heterotrimeric G-protein Galphaq and excitable cells in C. elegans

1 reference

12 December 2020

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

1 reference

12 December 2020

Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans

1 reference

12 December 2020

Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer

1 reference

12 December 2020

Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

1 reference

12 December 2020

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

1 reference

12 December 2020

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

1 reference

12 December 2020

The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway.

1 reference

12 December 2020

The C. elegans vulval induction gene lin-2 encodes a member of the MAGUK family of cell junction proteins

1 reference

12 December 2020

LET-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction

1 reference

12 December 2020

A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans.

1 reference

12 December 2020

lin-12 and glp-1 are required zygotically for early embryonic cellular interactions and are regulated by maternal GLP-1 signaling in Caenorhabditis elegans.

1 reference

12 December 2020

The family of Caenorhabditis elegans tyrosine kinase receptors: similarities and differences with mammalian receptors.

1 reference

12 December 2020

let-756, a C. elegans fgf essential for worm development.

1 reference

12 December 2020

NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans

1 reference

12 December 2020

C. elegans vulval development as a model system to study the cancer biology of EGFR signaling

1 reference

12 December 2020

The Ras-MAPK pathway is important for olfaction in Caenorhabditis elegans.

1 reference

12 December 2020

Association of membrane-associated guanylate kinase-interacting protein-1 with Raf-1.

1 reference

12 December 2020

The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf

1 reference

12 December 2020

Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals

1 reference

12 December 2020

ARK-1 inhibits EGFR signaling in C. elegans

1 reference

12 December 2020

Docking domains and substrate-specificity determination for MAP kinases

1 reference

12 December 2020

Mechanisms controlling sex myoblast migration in Caenorhabditis elegans hermaphrodites

1 reference

12 December 2020

Ras pathway specificity is determined by the integration of multiple signal-activated and tissue-restricted transcription factors.

1 reference

12 December 2020

Combinatorial signaling in the specification of unique cell fates

1 reference

12 December 2020

Caenorhabditis elegans lin-25: a study of its role in multiple cell fate specification events involving Ras and the identification and characterization of evolutionarily conserved domains

1 reference

12 December 2020

Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development

1 reference

12 December 2020

A sperm cytoskeletal protein that signals oocyte meiotic maturation and ovulation

1 reference

12 December 2020

All in the family: the BTB/POZ, KRAB, and SCAN domains

1 reference

12 December 2020

Positive and negative regulation of Raf kinase activity and function by phosphorylation

1 reference

12 December 2020

The C. elegans E2F- and DP-related proteins are required for embryonic asymmetry and negatively regulate Ras/MAPK signaling.

1 reference

12 December 2020

dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development

1 reference

12 December 2020

LAD-1, the Caenorhabditis elegans L1CAM homologue, participates in embryonic and gonadal morphogenesis and is a substrate for fibroblast growth factor receptor pathway-dependent phosphotyrosine-based signaling

1 reference

12 December 2020

The Caenorhabditis elegans EGL-15 signaling pathway implicates a DOS-like multisubstrate adaptor protein in fibroblast growth factor signal transduction

1 reference

12 December 2020

Fibroblast growth factor signaling in Caenorhabditis elegans

1 reference

12 December 2020

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

1 reference

12 December 2020

Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates

1 reference

12 December 2020

C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation

1 reference

12 December 2020

A heterochromatin protein 1 homologue in Caenorhabditis elegans acts in germline and vulval development

1 reference

12 December 2020

Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit

1 reference

12 December 2020

Caenorhabditis elegans inositol 5-phosphatase homolog negatively regulates inositol 1,4,5-triphosphate signaling in ovulation

1 reference

12 December 2020

Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling

1 reference

12 December 2020

A lin-45 raf enhancer screen identifies eor-1, eor-2 and unusual alleles of Ras pathway genes in Caenorhabditis elegans

1 reference

12 December 2020

Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling

1 reference

12 December 2020

Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction

1 reference

12 December 2020

Complexities in ETS-domain transcription factor function and regulation: lessons from the TCF (ternary complex factor) subfamily. The Colworth Medal Lecture.

1 reference

12 December 2020

Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans

1 reference

12 December 2020

Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers

1 reference

12 December 2020

C. elegans EOR-1/PLZF and EOR-2 positively regulate Ras and Wnt signaling and function redundantly with LIN-25 and the SUR-2 Mediator component

1 reference

12 December 2020

The C.elegans MAPK phosphatase LIP-1 is required for the G(2)/M meiotic arrest of developing oocytes

1 reference

12 December 2020

Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling

1 reference

12 December 2020

A component of the transcriptional mediator complex inhibits RAS-dependent vulval fate specification in C. elegans

1 reference

12 December 2020

Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans

1 reference

12 December 2020

An Eph receptor sperm-sensing control mechanism for oocyte meiotic maturation in Caenorhabditis elegans

1 reference

12 December 2020

UNC-52/perlecan affects gonadal leader cell migrations in C. elegans hermaphrodites through alterations in growth factor signaling

1 reference

12 December 2020

Cis regulatory requirements for vulval cell-specific expression of the caenorhabditis elegans fibroblast growth factor gene egl-17

1 reference

12 December 2020

TheC. elegansG-protein-coupled receptor SRA-13 inhibits RAS/MAPK signalling during olfaction and vulval development

1 reference

12 December 2020

RAS oncogenes: the first 30 years.

1 reference

12 December 2020

Galphao/i and Galphas signaling function in parallel with the MSP/Eph receptor to control meiotic diapause in C. elegans

1 reference

12 December 2020

Genome-wide RNAi screening identifies protein damage as a regulator of osmoprotective gene expression

1 reference

12 December 2020

C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival

1 reference

12 December 2020

Identification of cis-regulatory elements from the C. elegans Hox gene lin-39 required for embryonic expression and for regulation by the transcription factors LIN-1, LIN-31 and LIN-39.

1 reference

12 December 2020

The molecular diversity of glycosaminoglycans shapes animal development.

1 reference

12 December 2020

Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation

1 reference

12 December 2020

The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.

1 reference

12 December 2020

Lipoprotein receptors and a disabled family cytoplasmic adaptor protein regulate EGL-17/FGF export in C. elegans

1 reference

12 December 2020

Hox gene evolution in nematodes: novelty conserved

1 reference

12 December 2020

A cell-specific enhancer that specifies lin-3 expression in the C. elegans anchor cell for vulval development

1 reference

12 December 2020

Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase

1 reference

12 December 2020

Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development

1 reference

12 December 2020

C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites

1 reference

12 December 2020

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins

1 reference

12 December 2020

A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling

1 reference

12 December 2020

Differential functions of the C. elegans FGF receptor in axon outgrowth and maintenance of axon position.

1 reference

12 December 2020

FGF signaling functions in the hypodermis to regulate fluid balance in C. elegans.

1 reference

12 December 2020

The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans

1 reference

12 December 2020

Inositol 1,4,5-trisphosphate signaling regulates rhythmic contractile activity of myoepithelial sheath cells in Caenorhabditis elegans

1 reference

12 December 2020

Argos inhibits epidermal growth factor receptor signalling by ligand sequestration

1 reference

12 December 2020

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans

1 reference

12 December 2020

Functional phylogeny relates LET-756 to fibroblast growth factor 9

1 reference

12 December 2020

C. elegans LIN-18 is a Ryk ortholog and functions in parallel to LIN-17/Frizzled in Wnt signaling

1 reference

12 December 2020

FGF and PI3 kinase signaling pathways antagonistically modulate sex muscle differentiation in C. elegans.

1 reference

12 December 2020

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

1 reference

12 December 2020

The Caenorhabditis elegans male: Postembryonic development of nongonadal structures

1 reference

12 December 2020

Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans

1 reference

12 December 2020

Fine structure of the Caenorhabditis elegans secretory-excretory system.

1 reference

12 December 2020

The lin-12 locus specifies cell fates in Caenorhabditis elegans

1 reference

12 December 2020

The embryonic cell lineage of the nematode Caenorhabditis elegans

1 reference

12 December 2020

Functional study of the Caenorhabditis elegans secretory-excretory system using laser microsurgery

1 reference

12 December 2020

Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans

1 reference

12 December 2020

Genes that affect cell fates during the development of Caenorhabditis elegans

1 reference

12 December 2020

The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways.

1 reference

12 December 2020

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

1 reference

12 December 2020

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

1 reference

12 December 2020

The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

1 reference

12 December 2020

The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans

1 reference

12 December 2020

Analysis of dominant-negative mutations of the Caenorhabditis elegans let-60 ras gene

1 reference

12 December 2020

Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions

1 reference

12 December 2020

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1 reference

12 December 2020

A normally attractive cell interaction is repulsive in two C. elegans mesodermal cell migration mutants

1 reference

12 December 2020

The gene lin-3 encodes an inductive signal for vulval development in C. elegans

1 reference

12 December 2020

C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation.

1 reference

12 December 2020

lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulval development

1 reference

12 December 2020

unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein.

1 reference

12 December 2020

Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation

1 reference

12 December 2020

A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans

1 reference

12 December 2020

The GRB2/Sem-5 adaptor protein

1 reference

12 December 2020

The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development

1 reference

12 December 2020

lin-25, a gene required for vulval induction in Caenorhabditis elegans

1 reference

12 December 2020

Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans

1 reference

12 December 2020

MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events

1 reference

12 December 2020

The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK

1 reference

12 December 2020

Sequential signalling during Caenorhabditis elegans vulval induction

1 reference

12 December 2020

The Caenorhabditis elegans lin-12 gene mediates induction of ventral uterine specialization by the anchor cell

1 reference

12 December 2020

sli-1, a negative regulator of let-23-mediated signaling in C. elegans

1 reference

12 December 2020

The lin-3/let-23 pathway mediates inductive signalling during male spicule development in Caenorhabditis elegans

1 reference

12 December 2020

Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates

1 reference

12 December 2020

1 reference

12 December 2020

Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans

1 reference

12 December 2020

Mosaic analysis of the let-23 gene function in vulval induction of Caenorhabditis elegans

1 reference

12 December 2020

sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction.

1 reference

12 December 2020

An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites

1 reference

12 December 2020

Control of oocyte growth and meiotic maturation in Caenorhabditis elegans

1 reference

12 December 2020

Coordinated lumen contraction and expansion during vulval tube morphogenesis in Caenorhabditis elegans.

1 reference

12 December 2020

egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditis elegans

1 reference

12 December 2020

Caenorhabditis elegans HOM-C genes regulate the response of vulval precursor cells to inductive signal

1 reference

12 December 2020

Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans

1 reference

12 December 2020

The protein kinase KSR interacts with 14-3-3 protein and Raf.

1 reference

12 December 2020

Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase

1 reference

12 December 2020

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

1 reference

12 December 2020

EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans.

1 reference

12 December 2020

The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development

1 reference

12 December 2020

The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling.

1 reference

12 December 2020

Inositol trisphosphate mediates a RAS-independent response to LET-23 receptor tyrosine kinase activation in C. elegans

1 reference

12 December 2020

Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.

1 reference

12 December 2020

Post-embryonic expression pattern of C. elegans let-60 ras reporter constructs.

1 reference

12 December 2020

Interactions of EGF, Wnt and HOM-C genes specify the P12 neuroectoblast fate in C. elegans.

1 reference

12 December 2020

clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans

1 reference

12 December 2020

MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction

1 reference

12 December 2020

Characterization of the C. elegans gap-2 gene encoding a novel Ras-GTPase activating protein and its possible role in larval development

1 reference

12 December 2020

soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling

1 reference

12 December 2020

Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction

1 reference

12 December 2020

SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans

1 reference

12 December 2020

Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase

1 reference

12 December 2020

The beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development.

1 reference

12 December 2020

Genetic analysis of the Caenorhabditis elegans MAP kinase gene mpk-1

1 reference

12 December 2020

The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells

1 reference

12 December 2020

Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates

1 reference

12 December 2020

On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans

1 reference

12 December 2020

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

12 December 2020

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

1 reference

12 December 2020

Identification of Ce-AF-6, a novel Caenorhabditis elegans protein, as a putative Ras effector.

1 reference

12 December 2020

Reciprocal EGF signaling back to the uterus from the induced C. elegans vulva coordinates morphogenesis of epithelia

1 reference

12 December 2020

Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans

1 reference

12 December 2020

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

1 reference

12 December 2020

Basolateral localization of the Caenorhabditis elegans epidermal growth factor receptor in epithelial cells by the PDZ protein LIN-10.

1 reference

12 December 2020

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

1 reference

12 December 2020

A local, high-density, single-nucleotide polymorphism map used to clone Caenorhabditis elegans cdf-1

1 reference

12 December 2020

A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction

1 reference

12 December 2020

EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid

1 reference

12 December 2020

lin-35 Rb acts in the major hypodermis to oppose ras-mediated vulval induction in C. elegans

1 reference

12 December 2020

A pair as a minimum: the two fibroblast growth factors of the nematode Caenorhabditis elegans

1 reference

12 December 2020

Sumoylation of LIN-1 promotes transcriptional repression and inhibition of vulval cell fates.

1 reference

12 December 2020

RAS is regulated by the let-7 microRNA family

1 reference

12 December 2020

FGF signaling in flies and worms: more and more relevant to vertebrate biology.

1 reference

12 December 2020

The C. elegans homolog of the mammalian tumor suppressor Dep-1/Scc1 inhibits EGFR signaling to regulate binary cell fate decisions

1 reference

12 December 2020

Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans

1 reference

12 December 2020

Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling

1 reference

12 December 2020

LET-60 RAS modulates effects of insulin/IGF-1 signaling on development and aging in Caenorhabditis elegans

1 reference

12 December 2020

lin-1 has both positive and negative functions in specifying multiple cell fates induced by Ras/MAP kinase signaling in C. elegans

1 reference

12 December 2020

lin-8, which antagonizes Caenorhabditis elegans Ras-mediated vulval induction, encodes a novel nuclear protein that interacts with the LIN-35 Rb protein

1 reference

12 December 2020

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

1 reference

12 December 2020

LIP-1 phosphatase controls the extent of germline proliferation in Caenorhabditis elegans

1 reference

12 December 2020

Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion

1 reference

12 December 2020

Transcriptional upregulation of the C. elegans Hox gene lin-39 during vulval cell fate specification

1 reference

12 December 2020

The CRAL/TRIO and GOLD domain protein CGR-1 promotes induction of vulval cell fates in Caenorhabditis elegans and interacts genetically with the Ras signaling pathway

1 reference

12 December 2020

FGF negatively regulates muscle membrane extension in Caenorhabditis elegans

1 reference

12 December 2020

Intracellular trafficking of LET-756, a fibroblast growth factor of C. elegans, is controlled by a balance of export and nuclear signals

1 reference

12 December 2020

SynMuv genes redundantly inhibit lin-3/EGF expression to prevent inappropriate vulval induction in C. elegans

1 reference

12 December 2020

The adaptor protein soc-1/Gab1 modifies growth factor receptor output in Caenorhabditis elegans

1 reference

12 December 2020

Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development

1 reference

12 December 2020

The SynMuv genes of Caenorhabditis elegans in vulval development and beyond

1 reference

12 December 2020

The Mi-2 nucleosome-remodeling protein LET-418 is targeted via LIN-1/ETS to the promoter of lin-39/Hox during vulval development in C. elegans

1 reference

12 December 2020

Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development

1 reference

12 December 2020

Epidermal growth factor signaling induces behavioral quiescence in Caenorhabditis elegans

1 reference

12 December 2020

The C. elegans ROR receptor tyrosine kinase, CAM-1, non-autonomously inhibits the Wnt pathway

1 reference

12 December 2020

1 reference

12 December 2020

1 reference

12 December 2020

Genomic overview of protein kinases

1 reference

12 December 2020

Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development

1 reference

12 December 2020

Conserved regulation of MAP kinase expression by PUF RNA-binding proteins

1 reference

12 December 2020

Wnt signaling induces vulva development in the nematode Pristionchus pacificus.

1 reference

12 December 2020

The candidate MAP kinase phosphorylation substrate DPL-1 (DP) promotes expression of the MAP kinase phosphatase LIP-1 in C. elegans germ cells

1 reference

12 December 2020

Different isoforms of the C. elegans FGF receptor are required for attraction and repulsion of the migrating sex myoblasts

1 reference

12 December 2020

C. elegans La-related protein, LARP-1, localizes to germline P bodies and attenuates Ras-MAPK signaling during oogenesis

1 reference

12 December 2020

Ras oncogenes: split personalities

1 reference

12 December 2020

C. elegans anaplastic lymphoma kinase ortholog SCD-2 controls dauer formation by modulating TGF-beta signaling

1 reference

12 December 2020

Opposing Wnt pathways orient cell polarity during organogenesis

1 reference

12 December 2020

Tissue-specific functions of the Caenorhabditis elegans p120 Ras GTPase activating protein GAP-3.

1 reference

12 December 2020

Glycosphingolipids control the extracellular gradient of the Drosophila EGFR ligand Gurken.

1 reference

12 December 2020

The role of protease activity in ErbB biology

1 reference

12 December 2020

Wnt and EGF pathways act together to induce C. elegans male hook development

1 reference

12 December 2020

Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development

1 reference

12 December 2020

Lipocalin signaling controls unicellular tube development in the Caenorhabditis elegans excretory system

1 reference

12 December 2020

Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans

1 reference

12 December 2020

The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation

1 reference

12 December 2020

The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline

1 reference

12 December 2020

An unbiased screen identifies DEP-1 tumor suppressor as a phosphatase controlling EGFR endocytosis

1 reference

12 December 2020

N-Glycosylation regulates fibroblast growth factor receptor/EGL-15 activity in Caenorhabditis elegans in vivo

1 reference

12 December 2020

The roles of EGF and Wnt signaling during patterning of the C. elegans Bgamma/delta Equivalence Group

1 reference

12 December 2020

Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling.

1 reference

12 December 2020

Sperm and oocyte communication mechanisms controlling C. elegans fertility

1 reference

12 December 2020

The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation

1 reference

12 December 2020

MSP hormonal control of the oocyte MAP kinase cascade and reactive oxygen species signaling.

1 reference

12 December 2020

EOR-2 is an obligate binding partner of the BTB-zinc finger protein EOR-1 in Caenorhabditis elegans

1 reference

12 December 2020

Cell signaling by receptor tyrosine kinases

1 reference

12 December 2020

Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2.

1 reference

12 December 2020

Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC-gamma, and IP3R activation

1 reference

12 December 2020

Re-programming of C. elegans male epidermal precursor fates by Wnt, Hox, and LIN-12/Notch activities

1 reference

12 December 2020

The ERK-MAPK pathway regulates longevity through SKN-1 and insulin-like signaling in Caenorhabditis elegans

1 reference

12 December 2020

Klotho interferes with a novel FGF-signalling pathway and insulin/Igf-like signalling to improve longevity and stress resistance in Caenorhabditis elegans

1 reference

12 December 2020

Ras effector switching promotes divergent cell fates in C. elegans vulval patterning

1 reference

12 December 2020

Mechanistic principles of RAF kinase signaling

1 reference

12 December 2020

The cooperation of FGF receptor and Klotho is involved in excretory canal development and regulation of metabolic homeostasis in Caenorhabditis elegans.

1 reference

12 December 2020

Diverse transcription factor binding features revealed by genome-wide ChIP-seq in C. elegans

1 reference

12 December 2020

The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination

1 reference

12 December 2020

A RasGRP, C. elegans RGEF-1b, couples external stimuli to behavior by activating LET-60 (Ras) in sensory neurons

1 reference

12 December 2020

MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module

1 reference

12 December 2020

Heparan sulfate 6-O-sulfotransferase 1, a gene involved in extracellular sugar modifications, is mutated in patients with idiopathic hypogonadotrophic hypogonadism

1 reference

12 December 2020

Notch and Ras promote sequential steps of excretory tube development in C. elegans

1 reference

12 December 2020

EGF signalling activates the ubiquitin proteasome system to modulate C. elegans lifespan

1 reference

12 December 2020

Spatial regulation of lag-2 transcription during vulval precursor cell fate patterning in Caenorhabditis elegans

1 reference

12 December 2020

Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling

1 reference

12 December 2020

Interactions between subunits of the Mediator complex with gene-specific transcription factors

1 reference

12 December 2020

Regulating the regulator: post-translational modification of RAS

1 reference

12 December 2020

The Caenorhabditis elegans synthetic multivulva genes prevent ras pathway activation by tightly repressing global ectopic expression of lin-3 EGF

1 reference

12 December 2020

Behavioral and immune responses to infection require Gαq- RhoA signaling in C. elegans

1 reference

12 December 2020

RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans

1 reference

12 December 2020

Identifiers

DOI

10.1895/WORMBOOK.1.80.2

1 reference

13 October 2017

1 reference

13 October 2017

1 reference

PMCID

3885983