The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination (Q34714971)

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English	The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

4 August 2017

The LIN-15A and LIN-56 transcriptional regulators interact to negatively regulate EGF/Ras signaling in Caenorhabditis elegans vulval cell-fate determination (English)

1 reference

Europe PubMed Central

4 August 2017

Caenorhabditis elegans

0 references

Protein lin-56 CELE_ZK673.3

1 reference

GOA release 2020-03-11

EGF-like domain-containing protein;Protein lin-3 CELE_F36H1.4

1 reference

GOA release 2020-03-11

Protein lin-15A CELE_ZK678.1

1 reference

GOA release 2020-03-11

object named as

Adam M Saffer

2

0 references

Paul W. Sternberg

object named as

Paul W Sternberg

5

0 references

H. Robert Horvitz

6

object named as

H Robert Horvitz

1 reference

Europe PubMed Central

4 August 2017

author name string

Ewa M Davison

1

1 reference

Europe PubMed Central

4 August 2017

Linda S Huang

3

1 reference

Europe PubMed Central

4 August 2017

John DeModena

4

1 reference

Europe PubMed Central

4 August 2017

language of work or name

0 references

publication date

31 December 2010

1 reference

Europe PubMed Central

4 August 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

1 reference

Europe PubMed Central

4 August 2017

187

1 reference

Europe PubMed Central

4 August 2017

3

1 reference

Europe PubMed Central

4 August 2017

803-815

1 reference

Europe PubMed Central

4 August 2017

THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

LINC, a human complex that is related to pRB-containing complexes in invertebrates regulates the expression of G2/M genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

LIN-61, one of two Caenorhabditis elegans malignant-brain-tumor-repeat-containing proteins, acts with the DRM and NuRD-like protein complexes in vulval development but not in certain other biological processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Some C. elegans class B synthetic multivulva proteins encode a conserved LIN-35 Rb-containing complex distinct from a NuRD-like complex

1 reference

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The THAP-zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes

1 reference

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Epidermal growth factor receptor (EGFR) signaling in cancer

1 reference

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7 July 2018

lin-8, which antagonizes Caenorhabditis elegans Ras-mediated vulval induction, encodes a novel nuclear protein that interacts with the LIN-35 Rb protein

1 reference

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7 July 2018

Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans

1 reference

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7 July 2018

The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity

1 reference

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Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

1 reference

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7 July 2018

Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

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Genome annotation by high-throughput 5' RNA end determination

1 reference

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New Genes That Interact With lin-35 Rb to Negatively Regulate the let-60 ras Pathway in Caenorhabditis elegans

1 reference

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7 July 2018

The epidermal growth factor system in Caenorhabditis elegans

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The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase

1 reference

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7 July 2018

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

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Structural classification of zinc fingers: survey and summary

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Targeting RAS signalling pathways in cancer therapy

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The retinoblastoma tumour suppressor in development and cancer

1 reference

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7 July 2018

The Caenorhabditis elegans vulval morphogenesis gene sqv-4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The MEP-1 zinc-finger protein acts with MOG DEAH box proteins to control gene expression via the fem-3 3' untranslated region in Caenorhabditis elegans

1 reference

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7 July 2018

A global analysis of Caenorhabditis elegans operons

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7 July 2018

Functional requirement for histone deacetylase 1 in Caenorhabditis elegans gonadogenesis

1 reference

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7 July 2018

Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects

1 reference

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7 July 2018

fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

A heterochromatin protein 1 homologue in Caenorhabditis elegans acts in germline and vulval development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Rb targets histone H3 methylation and HP1 to promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Rb-mediated chromatin structure regulation and transcriptional repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The role of EGF-related peptides in tumor growth.

1 reference

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7 July 2018

The Rb/E2F pathway and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Zinc finger proteins: new insights into structural and functional diversity

1 reference

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7 July 2018

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

1 reference

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7 July 2018

Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes

1 reference

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7 July 2018

Caenorhabditis elegans lin-13, a member of the LIN-35 Rb class of genes involved in vulval development, encodes a protein with zinc fingers and an LXCXE motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Protein interaction mapping in C. elegans using proteins involved in vulval development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Sin meets NuRD and other tails of repression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The RING finger/B-box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

lin-35 and lin-53, two genes that antagonize a C. elegans Ras pathway, encode proteins similar to Rb and its binding protein RbAp48.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Vulval development in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Asymmetric distribution of the C. elegans HAM-1 protein in neuroblasts enables daughter cells to adopt distinct fates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Real time quantitative PCR

1 reference

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7 July 2018

A point mutation in the extracellular domain activates LET-23, the Caenorhabditis elegans epidermal growth factor receptor homolog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

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Isolation and genetic characterization of cell-lineage mutants of the nematode Caenorhabditis elegans

1 reference

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7 July 2018

Caenorhabditis elegans deficiency mapping

1 reference

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7 July 2018

The genetics of Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The multivulva phenotype of certain Caenorhabditis elegans mutants results from defects in two functionally redundant pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

A novel genetic system to detect protein-protein interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The unc-86 gene product couples cell lineage and cell identity in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

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Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences

1 reference

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7 July 2018

Muscle cell attachment in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

The gene lin-3 encodes an inductive signal for vulval development in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

7 July 2018

Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

C. elegans HIM-17 links chromatin modification and competence for initiation of meiotic recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

MEP-1 and a homolog of the NURD complex component Mi-2 act together to maintain germline-soma distinctions in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

C. elegans class B synthetic multivulva genes act in G(1) regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

dpl-1 DP and efl-1 E2F act with lin-35 Rb to antagonize Ras signaling in C. elegans vulval development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

The C. elegans Mi-2 chromatin-remodelling proteins function in vulval cell fate determination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes.

1 reference

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26 October 2018

The C. elegans gene lin-9,which acts in an Rb-related pathway, is required for gonadal sheath cell development and encodes a novel protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063674

26 October 2018

The expression, lamin-dependent localization and RNAi depletion phenotype for emerin in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21196525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21196525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK

1 reference

https://pubmed.ncbi.nlm.nih.gov/21196525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SynMuv genes redundantly inhibit lin-3/EGF expression to prevent inappropriate vulval induction in C. elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21196525

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[C. elegans: of neurons and genes]

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1534/GENETICS.110.124487

Identifiers

10.1534/GENETICS.110.124487

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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