Novel siRNA delivery strategy: a new "strand" in CNS translational medicine? (Q38091009)

28 August 2017

Novel siRNA delivery strategy: a new "strand" in CNS translational medicine? (English)

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28 August 2017

1

Lisa Gherardini

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28 August 2017

Giuseppe Bardi

2

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28 August 2017

Mariangela Gennaro

series ordinal

3

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28 August 2017

Tommaso Pizzorusso

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4

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28 August 2017

19 March 2013

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Cellular and Molecular Life Sciences

28 August 2017

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28 August 2017

71

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28 August 2017

1-20

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28 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s00018-013-1310-8

28 August 2017

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RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

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21 January 2018

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Immune responses against adenoviral vectors and their transgene products: a review of strategies for evasion.

21 January 2018

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Using non-coding small RNAs to develop therapies for Huntington's disease

21 January 2018

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Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

21 January 2018

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Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

21 January 2018

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Results from a phase I safety trial of hAADC gene therapy for Parkinson disease

21 January 2018

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21 January 2018

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AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trial

21 January 2018

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Gene therapy for late infantile neuronal ceroid lipofuscinosis: neurosurgical considerations.

21 January 2018

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Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.

21 January 2018

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Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

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Identification and design of peptides as a new drug delivery system for the brain.

21 January 2018

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Functional motor recovery from brain ischemic insult by carbon nanotube-mediated siRNA silencing

21 January 2018

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Gold nanorod--siRNA induces efficient in vivo gene silencing in the rat hippocampus

21 January 2018

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Nanotechnology approach for drug addiction therapy: gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons

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21 January 2018

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21 January 2018

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RNAi and small interfering RNAs in human disease therapeutic applications

21 January 2018

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Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model

21 January 2018

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Brain-targeting gene delivery and cellular internalization mechanisms for modified rabies virus glycoprotein RVG29 nanoparticles

21 January 2018

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Polymeric nanoparticles for the drug delivery to the central nervous system

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

21 January 2018

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Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.

21 January 2018

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Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice

21 January 2018

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Mature and precursor brain-derived neurotrophic factor have individual roles in the mouse olfactory bulb

21 January 2018

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Delivery of brain-derived neurotrophic factor via nose-to-brain pathway

21 January 2018

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RNAi silencing in mouse models of neurodegenerative diseases

21 January 2018

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Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Intranasal delivery of siRNA to the olfactory bulbs of mice via the olfactory nerve pathway.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Gene therapy in Alzheimer's disease - potential for disease modification

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Therapeutic potential of small interfering RNA for central nervous system diseases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Silencing neurodegenerative disease: bringing RNA interference to the clinic

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

RNA interference as a tool for Alzheimer's disease therapy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

RNAi applications in therapy development for neurodegenerative disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Regenerating islet-derived 1α (Reg-1α) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptor

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Lentivirus-expressed siRNA vectors against Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Gene therapy in mouse models of huntington disease.

21 January 2018

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Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.

21 January 2018

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Huntington disease: pathogenesis, biomarkers, and approaches to experimental therapeutics

21 January 2018

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The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity

21 January 2018

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NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Spatial and temporal requirements for huntingtin (Htt) in neuronal migration and survival during brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

A majority of Huntington's disease patients may be treatable by individualized allele-specific RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Five siRNAs targeting three SNPs may provide therapy for three-quarters of Huntington's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Allele-selective inhibition of huntingtin expression by switching to an miRNA-like RNAi mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Preclinical safety of RNAi-mediated HTT suppression in the rhesus macaque as a potential therapy for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

RNA knockdown as a potential therapeutic strategy in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Applications of lentiviral vectors for biology and gene therapy of neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Preclinical development of gene therapy for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

The aggravating role of the ubiquitin-proteasome system in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Ubiquitylation of synphilin-1 and alpha-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Siah-1 facilitates ubiquitination and degradation of synphilin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

α-Synuclein fate is determined by USP9X-regulated monoubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Differential neuroprotective effects of 14-3-3 proteins in models of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Chaperone-mediated autophagy markers in Parkinson disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Knockdown of GAD67 protein levels normalizes neuronal activity in a rat model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Is dopamine neurotransmission altered in prodromal schizophrenia? A review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Behavioral effects of non-viral mediated RNA interference of synapsin II in the medial prefrontal cortex of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Use of siRNA in knocking down of dopamine receptors, a possible therapeutic option in neuropsychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Retrogradely transported siRNA silences human mutant SOD1 in spinal cord motor neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Cdk5/p25-induced cytosolic PLA2-mediated lysophosphatidylcholine production regulates neuroinflammation and triggers neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Epigenetic regulation of motor neuron cell death through DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

New therapeutic targets for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Lentivirus-mediated transfer of MMP-9 shRNA provides neuroprotection following focal ischemic brain injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Therapeutic application of gene silencing MMP-9 in a middle cerebral artery occlusion-induced focal ischemia rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Matrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

The Notch pathway mediates expansion of a progenitor pool and neuronal differentiation in adult neural progenitor cells after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

SDF-1α secreted by human CD133-derived multipotent stromal cells promotes neural progenitor cell survival through CXCR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Minocycline-preconditioned neural stem cells enhance neuroprotection after ischemic stroke in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Evidence that gamma-secretase-mediated Notch signaling induces neuronal cell death via the nuclear factor-kappaB-Bcl-2-interacting mediator of cell death pathway in ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

The NCX3 isoform of the Na+/Ca2+ exchanger contributes to neuroprotection elicited by ischemic postconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Multipotent mesenchymal stromal cells increase tPA expression and concomitantly decrease PAI-1 expression in astrocytes through the sonic hedgehog signaling pathway after stroke (in vitro study).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

siRNA delivery to CNS cells using a membrane translocation peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Apoptosis signal-regulating kinase 1 (Ask1) targeted small interfering RNA on ischemic neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

CHOP silencing reduces acute brain injury in the rat model of subarachnoid hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Neurovascular protection reduces early brain injury after subarachnoid hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Pluronic-coated carbon nanotubes do not induce degeneration of cortical neurons in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Identification of chemosensitivity nodes for vinblastine through small interfering RNA high-throughput screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

In vivo specific delivery of c-Met siRNA to glioblastoma using cationic solid lipid nanoparticles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Delivery of small-interfering RNA (siRNA) to the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Angiogenesis and invasion in glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Molecular mechanisms of glioma cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

High-grade glioma motility reduced by genetic knockdown of KCC3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

miRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Knockdown of ubiquitin ligases in glioblastoma cancer stem cells leads to cell death and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

uPAR and cathepsin B inhibition enhanced radiation-induced apoptosis in gliomainitiating cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

An extensive invasive intracranial human glioblastoma xenograft model: role of high level matrix metalloproteinase 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

NFκB inhibitors induce cell death in glioblastomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Notch signaling pathway and cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

IL-8 is a mediator of NF-κB induced invasion by gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Regulation of cell signalling by uPAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Synergistic induction of apoptosis in brain cancer cells by targeted codelivery of siRNA and anticancer drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Glioma growth inhibition in vitro and in vivo by single chain variable fragments of the transferrin receptor conjugated to survivin small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Bortezomib sensitizes malignant human glioma cells to TRAIL, mediated by inhibition of the NF-{kappa}B signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

RNA interference and nonviral targeted gene therapy of experimental brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Bevacizumab in the treatment of high-grade gliomas: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

c-Met-targeted RNA interference inhibits growth and metastasis of glioma U251 cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Phosphatase and tensin homolog reconstruction and vascular endothelial growth factor knockdown synergistically inhibit the growth of glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

The epidermal growth factor receptor as a therapeutic target in glioblastoma multiforme and other malignant neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

B4GALNT3 expression predicts a favorable prognosis and suppresses cell migration and invasion via β₁ integrin signaling in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

2-Methoxyestradiol induced Bax phosphorylation and apoptosis in human retinoblastoma cells via p38 MAPK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Reversal of stathmin-mediated microtubule destabilization sensitizes retinoblastoma cells to a low dose of antimicrotubule agents: a novel synergistic therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Treatment with connexin 46 siRNA suppresses the growth of human Y79 retinoblastoma cell xenografts in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Inhibition of oxygen-induced retinopathy in RTP801-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Translational investigation and treatment of neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

siRNA relieves chronic neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Angiopoietin 2 mediates the differentiation and migration of neural progenitor cells in the subventricular zone after stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Role of M2, M3, and M4 muscarinic receptor subtypes in the spinal cholinergic control of nociception revealed using siRNA in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Investigation of TRPV1 loss-of-function phenotypes in transgenic shRNA expressing and knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Calcium regulation by thermo- and osmosensing transient receptor potential vanilloid channels (TRPVs) in human conjunctival epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1310-8

Brain-targeting study of stearic acid-grafted chitosan micelle drug-delivery system

21 January 2018

1 reference

12 December 2020

Effective adoptive transfer of haploidentical tumor-specific T cells in B16-melanoma bearing mice.

1 reference

12 December 2020

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

1 reference

12 December 2020

The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke

1 reference

12 December 2020

Motor neuron disease: Misfolded wild-type SOD1 may link sporadic and familial ALS

1 reference

12 December 2020

A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain

1 reference

12 December 2020

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents

1 reference

12 December 2020

Protein functionalized tramadol-loaded PLGA nanoparticles: preparation, optimization, stability and pharmacodynamic studies

1 reference

12 December 2020

Short hairpin RNA targeting survivin inhibits growth and angiogenesis of glioma U251 cells

1 reference

12 December 2020

Olfactory targeting through intranasal delivery of biopharmaceutical drugs to the brain: current development

1 reference

12 December 2020

Evaluation of the siRNA PF-04523655 versus ranibizumab for the treatment of neovascular age-related macular degeneration (MONET Study)

1 reference

12 December 2020

The effects of siRNA-mediated RGS4 gene silencing on the whole genome transcription profile: implications for schizophrenia.

1 reference

12 December 2020

The therapeutic potential of siRNA in gene therapy of neurodegenerative disorders

1 reference

12 December 2020

Age-related macular degeneration

1 reference

12 December 2020

Design of functional small interfering RNAs targeting amyotrophic lateral sclerosis-associated mutant alleles.

1 reference

12 December 2020

Genetic and pharmacological basis for therapeutic inhibition of beta- and gamma-secretases in mouse models of Alzheimer's memory deficits.

1 reference

12 December 2020

Increased brain radioactivity by intranasal P-labeled siRNA dendriplexes within in situ-forming mucoadhesive gels

1 reference

12 December 2020

Knockdown of cathepsin B and uPAR inhibits CD151 and α3β1 integrin-mediated cell adhesion and invasion in glioma

1 reference

12 December 2020

Modification of small interfering RNAs to prevent off-target effects by the sense strand

1 reference

12 December 2020

Dysbindin-1, a schizophrenia-related protein, facilitates neurite outgrowth by promoting the transcriptional activity of p53

1 reference

12 December 2020

Targeting BACE with small inhibitory nucleic acids - a future for Alzheimer's disease therapy?

1 reference

12 December 2020

uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells

1 reference

12 December 2020

Metabolic remodeling precedes mitochondrial outer membrane permeabilization in human glioma xenograft cells

1 reference

12 December 2020

The therapeutic potential of LNA-modified siRNAs: reduction of off-target effects by chemical modification of the siRNA sequence

1 reference

12 December 2020

Mitochondrial dysfunction in Parkinson's disease

1 reference

12 December 2020

Nature and nurture in neuropsychiatric genetics: where do we stand?

1 reference

12 December 2020

Widespread suppression of huntingtin with convection-enhanced delivery of siRNA

1 reference

12 December 2020

10.1007/S00018-013-1310-8

Identifiers

DOI

1 reference

release_gow746jkxbeshh6lrw3tntiggq

28 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gow746jkxbeshh6lrw3tntiggq

24 November 2022

mapped directly with Wikidata item

1 reference