Emerging roles of RB family: new defense mechanisms against tumor progression (Q38034093)

27 August 2017

Emerging roles of RB family: new defense mechanisms against tumor progression (English)

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27 August 2017

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5

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27 August 2017

Paola Indovina

1

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27 August 2017

Eleonora Marcelli

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2

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27 August 2017

Nadia Casini

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3

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27 August 2017

Valeria Rizzo

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4

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27 August 2017

1 March 2013

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Journal of Cellular Physiology

27 August 2017

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27 August 2017

228

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27 August 2017

525-535

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27 August 2017

3

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Phosphorylated retinoblastoma protein complexes with pp32 and inhibits pp32-mediated apoptosis

27 August 2017

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Mammalian SMC3 C-terminal and coiled-coil protein domains specifically bind palindromic DNA, do not block DNA ends, and prevent DNA bending

21 January 2018

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Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence

21 January 2018

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A critical role for telomeres in suppressing and facilitating carcinogenesis

21 January 2018

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The signals and pathways activating cellular senescence

21 January 2018

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Nucleotide deficiency promotes genomic instability in early stages of cancer development

21 January 2018

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p53 ubiquitination: Mdm2 and beyond

21 January 2018

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The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

21 January 2018

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Retinoblastoma susceptibility gene product pRB activates hypoxia-inducible factor-1 (HIF-1).

21 January 2018

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Cellular mechanisms of tumour suppression by the retinoblastoma gene.

21 January 2018

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Cellular senescence, cancer and aging: the telomere connection

21 January 2018

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Cellular senescence: when bad things happen to good cells

21 January 2018

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Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.

21 January 2018

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Coordinated regulation of life and death by RB.

21 January 2018

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Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence

21 January 2018

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Critical role of the Rb family in myoblast survival and fusion

21 January 2018

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Opposing roles of pRB and p107 in adipocyte differentiation

21 January 2018

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The retinoblastoma family: twins or distant cousins?

21 January 2018

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Shared role of the pRB-related p130 and p107 proteins in limb development

21 January 2018

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Pocket proteins and cell cycle control

21 January 2018

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 January 2018

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Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

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Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin

21 January 2018

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pRb: master of differentiation. Coupling irreversible cell cycle withdrawal with induction of muscle-specific transcription.

21 January 2018

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pRb2/p130: a new candidate for retinoblastoma tumor formation

21 January 2018

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Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma.

21 January 2018

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Induction of a retinoblastoma phosphatase activity by anticancer drugs accompanies p53-independent G1 arrest and apoptosis

21 January 2018

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Retinoblastoma family genes

21 January 2018

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Lifetime risks of common cancers among retinoblastoma survivors

21 January 2018

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Links between replication, recombination and genome instability in eukaryotes

21 January 2018

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A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

21 January 2018

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Involvement of RB gene family in tumor angiogenesis.

21 January 2018

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Cell cycle control and beyond: emerging roles for the retinoblastoma gene family

21 January 2018

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Retinoic acid- and bone morphogenetic protein 4-induced apoptosis in P19 embryonal carcinoma cells requires p27.

21 January 2018

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Role of Rb family in the epigenetic definition of chromatin.

21 January 2018

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Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

21 January 2018

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Cyclin D3 promotes myogenic differentiation and Pax7 transcription

21 January 2018

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21 January 2018

The Hallmarks of Cancer

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Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

21 January 2018

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Cell cycle checkpoints, genomic integrity, and cancer

21 January 2018

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THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

21 January 2018

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Rb2/p130 is the dominating pocket protein in the p53-p21 DNA damage response pathway leading to senescence

21 January 2018

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Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

21 January 2018

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RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts.

21 January 2018

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Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells

21 January 2018

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Aberrant regulation of survivin by the RB/E2F family of proteins

21 January 2018

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Role of RB and RB2/P130 genes in marrow stromal stem cells plasticity.

21 January 2018

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Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors

21 January 2018

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Cooperation between p53 and p130(Rb2) in induction of cellular senescence

21 January 2018

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The essence of senescence

21 January 2018

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Id2 mediates tumor initiation, proliferation, and angiogenesis in Rb mutant mice.

21 January 2018

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Inactivation of the retinoblastoma susceptibility gene in human breast cancers

21 January 2018

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 January 2018

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The retinoblastoma protein is linked to the activation of Ras.

21 January 2018

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New roles for the RB tumor suppressor protein

21 January 2018

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21 January 2018

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Tumor suppression by Ink4a-Arf: progress and puzzles

21 January 2018

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Loss of pRB causes centromere dysfunction and chromosomal instability

21 January 2018

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Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

21 January 2018

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

21 January 2018

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Direct coupling of the cell cycle and cell death machinery by E2F.

21 January 2018

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

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Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle

21 January 2018

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pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation

21 January 2018

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Dynamic transcriptional regulatory complexes, including E2F4, p107, p130, and Sp1, control fibroblast growth factor receptor 1 gene expression during myogenesis.

21 January 2018

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Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

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Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.

21 January 2018

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Cellular senescence in vivo: a barrier to tumorigenesis

21 January 2018

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Role of the retinoblastoma pathway in senescence triggered by repression of the human papillomavirus E7 protein in cervical carcinoma cells.

21 January 2018

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Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis.

21 January 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

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Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

21 January 2018

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Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells

21 January 2018

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Apoptosis in cancer--implications for therapy

21 January 2018

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Mad2 is a critical mediator of the chromosome instability observed upon Rb and p53 pathway inhibition.

21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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Rb Regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation.

21 January 2018

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The INK4A/ARF locus and its two gene products

21 January 2018

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Retinoblastoma family proteins have distinct functions in pulmonary epithelial cells in vivo critical for suppressing cell growth and tumorigenesis

21 January 2018

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Regulation of cell lineage specification by the retinoblastoma tumor suppressor

21 January 2018

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Mad2 overexpression promotes aneuploidy and tumorigenesis in mice

21 January 2018

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RB loss promotes aberrant ploidy by deregulating levels and activity of DNA replication factors.

21 January 2018

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Gene expression changes in response to E2F1 activation.

21 January 2018

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From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway

21 January 2018

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Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression

21 January 2018

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Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

21 January 2018

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A G1 checkpoint mediated by the retinoblastoma protein that is dispensable in terminal differentiation but essential for senescence

21 January 2018

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The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

21 January 2018

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Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

21 January 2018

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Protein phosphatase 1alpha-mediated stimulation of apoptosis is associated with dephosphorylation of the retinoblastoma protein

21 January 2018

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The retinoblastoma protein and cell cycle control

21 January 2018

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Mechanism of active transcriptional repression by the retinoblastoma protein

21 January 2018

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pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.

21 January 2018

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Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

21 January 2018

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Retinoblastoma protein enhances the fidelity of chromosome segregation mediated by hsHec1p

21 January 2018

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Apaf-1 is a transcriptional target for E2F and p53

21 January 2018

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Executing Cell Senescence

21 January 2018

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21 January 2018

Senescence comes of age

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Deregulated MAPK Activity Prevents Adipocyte Differentiation of Fibroblasts Lacking the Retinoblastoma Protein

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24170

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27 August 2017

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