Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases? (Q38027902)

27 August 2017

Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases? (English)

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27 August 2017

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Marta Di Carlo

1

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27 August 2017

Daniela Giacomazza

2

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27 August 2017

Pasquale Picone

3

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27 August 2017

Domenico Nuzzo

4

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27 August 2017

Pier Luigi San Biagio

5

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27 August 2017

14 August 2012

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27 August 2017

Free Radical Research

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27 August 2017

46

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27 August 2017

11

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27 August 2017

1327-1338

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Amyloid deposition as the central event in the aetiology of Alzheimer's disease

27 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Unraveling the mechanisms involved in motor neuron degeneration in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Apoptosis in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Metal-dependent generation of reactive oxygen species from amyloid proteins implicated in neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Insulin-activated Akt rescues Aβ oxidative stress-induced cell death by orchestrating molecular trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Glutathione, oxidative stress and neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Oxidative stress, glutamate, and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Free radical theory of aging

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Temperature-dependent trade-offs between longevity and fertility in the Drosophila mutant, methuselah

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Oxidative stress as a causal factor in differentiation and aging: a unifying hypothesis

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

The mitochondrial free radical theory of ageing--where do we stand?

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondrial decay in aging

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Hydrogen peroxide release by mitochondria increases during aging

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

The neurodegenerative mitochondriopathies

21 January 2018

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https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Cyclophilin D deficiency improves mitochondrial function and learning/memory in aging Alzheimer disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondrial complex I deficiency in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondrial dysfunction and its role in motor neuron degeneration in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

A quantitative histochemical assay for activities of mitochondrial electron transport chain complexes in mouse spinal cord sections.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Quantitative analysis of complex protein mixtures using isotope-coded affinity tags

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Proteomic analysis of protein oxidation in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Proteomic identification of nitrated proteins in Alzheimer's disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Mitochondrial proteomics in free radical research.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

The neuronal microRNA system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

MicroRNA-9 controls the expression of Granuphilin/Slp4 and the secretory response of insulin-producing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

MicroRNA-9 inhibits ovarian cancer cell growth through regulation of NF-kappaB1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Epigenetics: a historical overview

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

DNA methylation patterns and epigenetic memory

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Epigenetic biomarkers for human cancer: the time is now.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Age-specific epigenetic drift in late-onset Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Identification and characterization of OGG1 mutations in patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Neuropsychological studies in children with elevated tooth-lead concentrations. II. Extended study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Occupational metal exposures and the risk of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Lead exposure and amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

ApoE genotype, past adult lead exposure, and neurobehavioral function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Factors contributing to the outcome of oxidative damage to nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2012.714466

Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1073/PNAS.0409713102

Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study.

30 October 2021

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1016/S0140-6736(04)16983-3

10.3109/10715762.2012.714466

30 October 2021

Identifiers

DOI

1 reference

release_m37nlszosvdnzbya5zl4jhrnca

27 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/m37nlszosvdnzbya5zl4jhrnca

mapped directly with Wikidata item

24 November 2022

based on heuristic

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