MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function (Q39545068)

12 September 2017

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function (English)

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Xavier Estivill i Pallejà

12 September 2017

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12 September 2017

Elena Miñones-Moyano

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Raquel Rabionet

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Raquel Rabionet

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Isidro Ferrer

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Isidre Ferrer

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12 September 2017

Sílvia Porta

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12 September 2017

Georgia Escaramís

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12 September 2017

Susana Iraola

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12 September 2017

Birgit Kagerbauer

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12 September 2017

Yolanda Espinosa-Parrilla

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12 September 2017

Eulàlia Martí

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12 September 2017

language of work or name

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10 May 2011

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12 September 2017

Human Molecular Genetics

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12 September 2017

20

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12 September 2017

15

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12 September 2017

3067-3078

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Staging of brain pathology related to sporadic Parkinson's disease

12 September 2017

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Stages in the development of Parkinson's disease-related pathology

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Parkinson's disease: mechanisms and models

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Genetics of Parkinson's disease and parkinsonism

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Pathogenic mutations in Parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Genetic basis of Parkinson disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Posttranscriptional control of neuronal development by microRNA networks

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

21 January 2018

microRNAs at the synapse

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Revisiting the principles of microRNA target recognition and mode of action

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Small silencing RNAs: an expanding universe

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

MicroRNAs and deregulated gene expression networks in neurodegeneration

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

A MicroRNA feedback circuit in midbrain dopamine neurons

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Repression of alpha-synuclein expression and toxicity by microRNA-7.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

DJ-1 has a role in antioxidative stress to prevent cell death

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Methylation-associated silencing of microRNA-34b/c in gastric cancer and its involvement in an epigenetic field defect

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinson disease and in dementia with Lewy bodies.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Complex I deficiency in Parkinson's disease frontal cortex

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Early involvement of the cerebral cortex in Parkinson's disease: convergence of multiple metabolic defects

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Phosphorylation of tau and alpha-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related alpha-synucleinopathies.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Proteinase K-resistant alpha-synuclein is deposited in presynapses in human Lewy body disease and A53T alpha-synuclein transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Involvement of the cerebellothalamocortical pathway in Parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Motor activation in multiple system atrophy and Parkinson disease: a PET study

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Mitochondrial complex I deficiency in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Mitochondria in the aetiology and pathogenesis of Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Differential DJ-1 gene expression in Parkinson's disease.

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

The role of parkin in familial and sporadic Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Mitochondrial dysfunction and oxidative damage in parkin-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

The PINK1/Parkin pathway regulates mitochondrial morphology

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

A powerful and flexible linear mixed model framework for the analysis of relative quantification RT-PCR data

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

A microRNA DNA methylation signature for human cancer metastasis

21 January 2018

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https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR210

21 January 2018

Identifiers

DOI

10.1093/HMG/DDR210

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release_fry4odjgebbjvp2zndxlglv5e4

12 September 2017

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