Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases (Q37996828)

26 August 2017

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases (English)

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26 August 2017

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3

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26 August 2017

Antero Salminen

1

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PubMed ID

22446749

26 August 2017

Johanna Ojala

series ordinal

2

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PubMed ID

22446749

26 August 2017

Anu Kauppinen

series ordinal

4

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26 August 2017

25 March 2012

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Cellular and Molecular Life Sciences

26 August 2017

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26 August 2017

69

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26 August 2017

18

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26 August 2017

2999-3013

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https://scigraph.springernature.com/pub.10.1007/s00018-012-0962-0

26 August 2017

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cites work

Life and death: metabolic rate, membrane composition, and life span of animals.

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondria and reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The mitochondrial free radical theory of ageing--where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Radical-free biology of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondrial alterations of retinal pigment epithelium in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Oxidative stress and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The network and the remodeling theories of aging: historical background and new perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Meta-analysis of age-related gene expression profiles identifies common signatures of aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammasomes: guardians of cytosolic sanctity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The inflammasomes: guardians of the body

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammasomes: current understanding and open questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NOD-like receptors and the innate immune system: coping with danger, damage and death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Adenovirus type 5 rupture of lysosomes leads to cathepsin B-dependent mitochondrial stress and production of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondria in innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The inflammasome: an integrated view

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The NLRP3 inflammasome: a sensor for metabolic danger?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The inflammasome NLRs in immunity, inflammation, and associated diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Active caspase-1 is a regulator of unconventional protein secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

A novel pathway for inducible nitric-oxide synthase activation through inflammasomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Central roles of NLRs and inflammasomes in viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Origin and physiological roles of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Molecular mechanisms involved in inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Oxidative stress caused by mitochondrial calcium overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The role of lysosomes in iron metabolism and recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammasomes are differentially expressed in cardiovascular and other tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Expression of NALP1 in cerebellar granule neurons stimulates apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NALP1 in vitiligo-associated multiple autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

A molecular platform in neurons regulates inflammation after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondrial dysfunction as a cause of ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondria: Sovereign of inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Uncoupling protein UCP2: when mitochondrial activity meets immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Circulating mitochondrial DAMPs cause inflammatory responses to injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondria in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Molecular mechanisms of inflammasome activation during microbial infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

DAMPs and inflammatory processes: the role of redox in the different outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Interplay between redox status and inflammasome activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

A role for mitochondria in NLRP3 inflammasome activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Autophagy shapes inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

High-mobility group box 1 (HMGB1) as a master regulator of innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Lipopolysaccharide-induced mitochondrial DNA depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Role of neutral sphingomyelinases in aging and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Ceramide forms channels in mitochondrial outer membranes at physiologically relevant concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Regulation of thioredoxin by ceramide in retinal pigment epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondrial peptides are potent immune activators that activate human neutrophils via FPR-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The cell-non-autonomous nature of electron transport chain-mediated longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammation and atherosclerosis: novel insights into plaque formation and destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mechanisms of vascular aging: new perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Cutting edge: Necrosis activates the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Phagocytosis of cells dying through autophagy induces inflammasome activation and IL-1β release in human macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Sensing damage by the NLRP3 inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Intravascular danger signals guide neutrophils to sites of sterile inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammatory arthritis in caspase 1 gene-deficient mice: contribution of proteinase 3 to caspase 1-independent production of bioactive interleukin-1beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Multiple interleukin-1beta-converting enzymes contribute to inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammasome-independent modulation of cytokine response by autophagy in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Elevated levels of tumor necrosis factor alpha and mortality in centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammatory mediators in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Increased IL-1beta in cortex of aged rats is accompanied by downregulation of ERK and PI-3 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondria and aging in the vascular system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammation, oxidative stress and lipids: the risk triad for atherosclerosis in gout

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Interleukin-1beta and caspase-1: players in the regulation of age-related cognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Blockade of caspase-1 increases neurogenesis in the aged hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Interleukin 18 in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Ex vivo cultures of microglia from young and aged rodent brain reveal age-related changes in microglial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Regulation of the aging process by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Does autophagy take a front seat in lifespan extension?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Impaired quality control of mitochondria: aging from a new perspective.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Mitochondrial control of autophagic lysosomal pathway in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The role of autophagy in β-cell lipotoxicity and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NF-kappaB is a negative regulator of IL-1beta secretion as revealed by genetic and pharmacological inhibition of IKKbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Anti-oxidative, anti-cancer and anti-inflammatory actions by thioredoxin 1 and thioredoxin-binding protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The involvement of thioredoxin and thioredoxin binding protein-2 on cellular proliferation and aging process

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Decreased thioredoxin and increased thioredoxin reductase levels in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Aging of the immune system as a prognostic factor for human longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The aging of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Microglia-aging: roles of microglial lysosome- and mitochondria-derived reactive oxygen species in brain aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

The aging immune system and its relationship to the development of chronic obstructive pulmonary disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Photoageing: mechanism, prevention and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Photoageing shows histological features of chronic skin inflammation without clinical and molecular abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Inflammatory markers in population studies of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Motif module map reveals enforcement of aging by continual NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Human NLRP3 inflammasome activation is Nox1-4 independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Hyperglycemia activates caspase-1 and TXNIP-mediated IL-1beta transcription in human adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Amino-Functionalized Polystyrene Nanoparticles Activate the NLRP3 Inflammasome in Human Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-0962-0

Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice

21 January 2018

1 reference

12 December 2020

Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium

1 reference

12 December 2020

Lipofuscin as an indicator of oxidative stress and aging.

1 reference

12 December 2020

Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteries

1 reference

12 December 2020

NALP1/NLRP1 genetic variants are associated with Alzheimer disease.

1 reference

12 December 2020

NF-kappaB activation by reactive oxygen species: fifteen years later

1 reference

12 December 2020

Mitochondrial uncoupling proteins

1 reference

12 December 2020

The uncoupling protein 2 modulates the cytokine balance in innate immunity

1 reference

12 December 2020

Interleukin 1 and interleukin 18 as mediators of inflammation and the aging process

1 reference

12 December 2020

IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway

1 reference

12 December 2020

Glycolysis links p53 function with NF-κB signaling: Impact on cancer and aging process

1 reference

12 December 2020

Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1β secretion by activating the NLRP3 inflammasome

1 reference

12 December 2020

A mitochondrial etiology of Alzheimer and Parkinson disease

1 reference

12 December 2020

Skin immune sentinels in health and disease

1 reference

12 December 2020

Caspase-5 expression is upregulated in lesional psoriatic skin

1 reference

12 December 2020

Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes

1 reference

12 December 2020

Mitochondria: commanders of innate immunity and disease?

1 reference

12 December 2020

Role of mitochondria in oxidative stress and ageing

1 reference

12 December 2020

The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes

1 reference

12 December 2020

Autophagy as an innate immunity paradigm: expanding the scope and repertoire of pattern recognition receptors.

1 reference

12 December 2020

Critical role of bone marrow apoptosis-associated speck-like protein, an inflammasome adaptor molecule, in neointimal formation after vascular injury in mice

1 reference

12 December 2020

Glycolysis links p53 function with NF-kappaB signaling: impact on cancer and aging process

1 reference

12 December 2020

10.1007/S00018-012-0962-0

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22446749