Mitochondria: Sovereign of inflammation? (Q37862153)

24 August 2017

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title

Mitochondria: Sovereign of inflammation? (English)

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24 August 2017

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1

Jürg Tschopp

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PubMed ID

21469137

24 August 2017

language of work or name

English

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publication date

1 May 2011

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European Journal of Immunology

24 August 2017

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24 August 2017

41

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24 August 2017

1196-1202

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24 August 2017

5

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

24 August 2017

1 reference

7 January 2021

The inflammasome NLRs in immunity, inflammation, and associated diseases

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

A clinical perspective of IL-1β as the gatekeeper of inflammation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The NLRP3 inflammasome: a sensor for metabolic danger?

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

CA-074Me protection against anthrax lethal toxin

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

NOX-free inflammasome activation

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https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

A role for mitochondria in NLRP3 inflammasome activation

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https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

VDAC: the channel at the interface between mitochondria and the cytosol.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

MAM: more than just a housekeeper

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Calcium, ATP, and ROS: a mitochondrial love-hate triangle

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Role of BNIP3 and NIX in cell death, autophagy, and mitophagy

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The apoptosome: signalling platform of cell death

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Lack of TXNIP protects beta-cells against glucotoxicity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Cryopyrin activates the inflammasome in response to toxins and ATP

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https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Physiological concentrations of K+ inhibit cytochrome c-dependent formation of the apoptosome

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Mitochondrial Ca2+-induced K+ influx increases respiration and enhances ROS production while maintaining membrane potential.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Thioredoxin-interacting protein is stimulated by glucose through a carbohydrate response element and induces beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

TXNIP regulates peripheral glucose metabolism in humans

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Medication-induced mitochondrial damage and disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The genetics and immunopathogenesis of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Interleukin-18 overproduction exacerbates the development of colitis with markedly infiltrated macrophages in interleukin-18 transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn's disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Mitochondrial dysfunction in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Interleukin-1beta mediates sleep alteration in rats with rotenone-induced parkinsonism.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Mitochondrial dysfunction and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The development of mitochondrial medicine

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Influenza virus activates inflammasomes via its intracellular M2 ion channel

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Toxicity of influenza A virus matrix protein 2 for mammalian cells is associated with its intrinsic proton-channeling activity

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141436

7 January 2021

Identifiers

DOI

10.1002/EJI.201141436

1 reference

24 August 2017

1 reference

PubMed ID

21469137