T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy (Q37948129)

25 August 2017

T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy (English)

1 reference

25 August 2017

1 reference

Laura M Snell

1

1 reference

25 August 2017

Gloria H Y Lin

2

1 reference

25 August 2017

Ann J McPherson

3

1 reference

25 August 2017

Theo J Moraes

4

1 reference

25 August 2017

Tania H Watts

5

1 reference

25 August 2017

1 November 2011

1 reference

25 August 2017

Immunological Reviews

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25 August 2017

244

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25 August 2017

1

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25 August 2017

197-217

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TNF/TNFR family members in costimulation of T cell responses

25 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Hypercostimulation through 4-1BB distorts homeostasis of immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

TCR-mediated activation promotes GITR upregulation in T cells and resistance to glucocorticoid-induced death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

GITR: a modulator of immune response and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

NF-kappaB and AP-1 regulate activation-dependent CD137 (4-1BB) expression in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Expression and function of 4-1BB during CD4 versus CD8 T cell responses in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

TNF family ligands define niches for T cell memory.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Immune regulation by 4-1BB and 4-1BBL: complexities and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Expression of CD137 (4-1BB) on human follicular dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Cutting edge: Expression of functional CD137 receptor by dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Functional CD137 receptors are expressed by eosinophils from patients with IgE-mediated allergic responses but not by eosinophils from patients with non-IgE-mediated eosinophilic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Agonist anti-CD137 mAb act on tumor endothelial cells to enhance recruitment of activated T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Cloning and characterization of GITR ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Functions of newly identified members of the tumor necrosis factor receptor/ligand superfamilies in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Expression of CD137 and its ligand in human neurons, astrocytes, and microglia: modulation by FGF-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Soluble CD137 (4-1BB) ligand is released following leukocyte activation and is found in sera of patients with hematological malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Sequence, structure, function, immunity: structural genomics of costimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Structural basis for self-association and receptor recognition of human TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The structural basis for the recognition of diverse receptor sequences by TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The Structure of the Trimer of Human 4-1BB Ligand Is Unique among Members of the Tumor Necrosis Factor Superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

1.8 Å structure of murine GITR ligand dimer expressed inDrosophila melanogasterS2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Structural basis for ligand-mediated mouse GITR activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Costimulation via glucocorticoid-induced TNF receptor in both conventional and CD25+ regulatory CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Cutting edge: the natural ligand for glucocorticoid-induced TNF receptor-related protein abrogates regulatory T cell suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF receptor-associated factor 2 in a novel fashion as an inhibitor of NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD27 Promotes Survival of Activated T Cells and Complements CD28 in Generation and Establishment of the Effector T Cell Pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

T cell co-stimulatory molecules other than CD28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

ERK-dependent Bim modulation downstream of the 4-1BB-TRAF1 signaling axis is a critical mediator of CD8 T cell survival in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Signalling pathways of the TNF superfamily: a double-edged sword

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The signaling adaptors and pathways activated by TNF superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Crystal Structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 Complexes: Affinity, Specificity, and Regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Structural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Regulation and function of NF-kappaB transcription factors in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The RING domain of TRAF2 plays an essential role in the inhibition of TNFalpha-induced cell death but not in the activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Regulation of TNFRSF and innate immune signalling complexes by TRAFs and cIAPs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD40 regulates the processing of NF-kappaB2 p100 to p52

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Glucocorticoid-induced TNF receptor functions as a costimulatory receptor that promotes survival in early phases of T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Tumor necrosis factor receptor (TNFR)-associated factor 5 is a critical intermediate of costimulatory signaling pathways triggered by glucocorticoid-induced TNFR in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Role of GITR in activation response of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Human 4-1BB (CD137) signals are mediated by TRAF2 and activate nuclear factor-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB and Ox40 are members of a tumor necrosis factor (TNF)-nerve growth factor receptor subfamily that bind TNF receptor-associated factors and activate nuclear factor kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Asymmetric recruitment of cIAPs by TRAF2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Immune responses in 4-1BB (CD137)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Enhanced CD4 T cell responsiveness in the absence of 4-1BB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

GITR/GITRL: more than an effector T cell co-stimulatory system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Stimulation of the glucocorticoid-induced TNF receptor family-related receptor on CD8 T cells induces protective and high-avidity T cell responses to tumor-specific antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Cutting edge: ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Addition of a prominent epitope affects influenza A virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

A switch in costimulation from CD28 to 4-1BB during primary versus secondary CD8 T cell response to influenza in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

In vivo kinetics of GITR and GITR ligand expression and their functional significance in regulating viral immunopathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Reduction of retrovirus-induced immunosuppression by in vivo modulation of T cells during acute infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Multimeric soluble CD40 ligand and GITR ligand as adjuvants for human immunodeficiency virus DNA vaccines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Co-immunization of mice with a retroviral DNA vaccine and GITRL-encoding plasmid augments vaccine-induced protection against retrovirus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Glucocorticoid-induced tumor necrosis factor receptor family-related protein triggering enhances HIV-specific CD4+ T cell cytokine secretion and protects HIV-specific CD4+ T cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Enhancement of HIV-specific CD8 T cell responses by dual costimulation with CD80 and CD137L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Combined CD137 (4-1BB) and adjuvant therapy generates a developing pool of peptide-specific CD8 memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB-mediated immunotherapy of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Peptide-specific CD8 T regulatory cells use IFN-gamma to elaborate TGF-beta-based suppression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Dendritic cells and Stat3 are essential for CD137-induced CD8 T cell activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Glucocorticoid-induced TNF receptor family related gene activation overcomes tolerance/ignorance to melanoma differentiation antigens and enhances antitumor immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Glucocorticoid-induced tumor necrosis factor receptor stimulation enhances the multifunctionality of adoptively transferred tumor antigen-specific CD8+ T cells with tumor regression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Immunostimulatory monoclonal antibodies for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Combinatorial therapy for liver metastatic colon cancer: dendritic cell vaccine and low-dose agonistic anti-4-1BB antibody co-stimulatory signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Optimising anti-tumour CD8 T-cell responses using combinations of immunomodulatory antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

OX40 ligation enhances primary and memory cytotoxic T lymphocyte responses in an immunotherapy for hepatic colon metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Established B16 tumors are rejected following treatment with GM-CSF-secreting tumor cell immunotherapy in combination with anti-4-1BB mAb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Combination CTLA-4 blockade and 4-1BB activation enhances tumor rejection by increasing T-cell infiltration, proliferation, and cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Soluble PD-1 facilitates 4-1BBL-triggered antitumor immunity against murine H22 hepatocarcinoma in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

T cell activation with systemic agonistic antibody versus local 4-1BB ligand gene delivery combined with interleukin-12 eradicate liver metastases of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

In vivo depletion of DC impairs the anti-tumor effect of agonistic anti-CD137 mAb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

The tumor microenvironment and metastatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

A novel form of 4-1BBL has better immunomodulatory activity than an agonistic anti-4-1BB Ab without Ab-associated severe toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

Costimulation through the CD137/4-1BB pathway protects human melanoma tumor-infiltrating lymphocytes from activation-induced cell death and enhances antitumor effector function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2011.01063.X

10.1111/J.1600-065X.2011.01063.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference