In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses (Q44493927)

3 December 2017

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses (English)

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3 December 2017

4

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3 December 2017

E Scott Halstead

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3 December 2017

Yvonne M Mueller

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2

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3 December 2017

John D Altman

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3

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3 December 2017

language of work or name

English

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publication date

20 May 2002

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3 December 2017

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3 December 2017

3

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3 December 2017

536-541

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6

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NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.

3 December 2017

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Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP.

21 January 2018

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4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells

21 January 2018

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Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

21 January 2018

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Human 4-1BB regulates CD28 co-stimulation to promote Th1 cell responses

21 January 2018

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4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses

21 January 2018

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CD28-independent, TRAF2-dependent costimulation of resting T cells by 4-1BB ligand

21 January 2018

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The activated type 1-polarized CD8(+) T cell population isolated from an effector site contains cells with flexible cytokine profiles.

21 January 2018

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Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

21 January 2018

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A previously unrecognized H-2D(b)-restricted peptide prominent in the primary influenza A virus-specific CD8(+) T-cell response is much less apparent following secondary challenge

21 January 2018

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Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy

21 January 2018

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Differential requirement for CD80 and CD80/CD86-dependent costimulation in the lung immune response to an influenza virus infection

21 January 2018

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Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model

21 January 2018

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Virus-specific CD8+ T-cell memory determined by clonal burst size

21 January 2018

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Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses

21 January 2018

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B7-CD28 costimulation unveils the hierarchy of tumor epitopes recognized by major histocompatibility complex class I-restricted CD8+ cytolytic T lymphocytes

21 January 2018

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Role of co-stimulation in CD8+ T cell activation.

21 January 2018

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4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity

21 January 2018

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Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

21 January 2018

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Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection

21 January 2018

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Response to influenza infection in mice with a targeted disruption in the interferon gamma gene

21 January 2018

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Phenotypic analysis of antigen-specific T lymphocytes

21 January 2018

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Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4

21 January 2018

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7 January 2021

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

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7 January 2021

4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination

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7 January 2021

A humanized anti--4-1BB monoclonal antibody suppresses antigen-induced humoral immune response in nonhuman primates

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7 January 2021

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire

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7 January 2021

Changes in the strength of co-stimulation through the B7/CD28 pathway alter functional T cell responses to altered peptide ligands

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7 January 2021

Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response

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7 January 2021

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

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7 January 2021

Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.

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7 January 2021

Progressive depletion of peripheral B lymphocytes in 4-1BB (CD137) ligand/I-Ealpha)-transgenic mice

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7 January 2021

Rapid induction of CD95 ligand and CD4+ T cell-mediated apoptosis by CD137 (4-1BB) costimulation

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7 January 2021

Identifiers

DOI

10.1038/NI798

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3 December 2017

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