Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. (Q40133919)

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30 December 2019

title

Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages (English)

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30 December 2019

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5

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30 December 2019

Motoyuki Otsuka

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30 December 2019

author name string

Young Jun Kang

1

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30 December 2019

Sung Ouk Kim

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30 December 2019

Shigeki Shimada

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Byoung S Kwon

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Tania H Watts

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Jiahuai Han

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language of work or name

English

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publication date

13 May 2007

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volume

8

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issue

6

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30 December 2019

page(s)

601-609

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The immunopathogenesis of sepsis

30 December 2019

cites work

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Toll-like receptor signalling

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Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor

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Molecular and biological characterization of human 4-1BB and its ligand

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Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells

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4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12.

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A signal through 4-1BB ligand inhibits receptor for activation of nuclear factor-kappaB ligand (RANKL)-induced osteoclastogenesis by increasing interferon (IFN)-beta production

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The TNF and TNF receptor superfamilies: integrating mammalian biology

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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Integrin-nucleated Toll-like receptor (TLR) dimerization reveals subcellular targeting of TLRs and distinct mechanisms of TLR4 activation and signaling

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Cytoplasmic domain-mediated dimerizations of toll-like receptor 4 observed by beta-lactamase enzyme fragment complementation

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CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses

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4-1BB-mediated immunotherapy of rheumatoid arthritis.

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Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

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Complex regulation of tumor necrosis factor mRNA turnover in lipopolysaccharide-activated macrophages

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REGULATION OF TNF-α EXPRESSION IN NORMAL MACROPHAGES: THE ROLE OF C/EBPβ

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A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo

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Differential activation of the transcription factor cyclic AMP response element binding protein (CREB) in macrophages following infection with pathogenic and nonpathogenic mycobacteria and role for CREB in tumor necrosis factor alpha production

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Regulation and signal transduction of toll-like receptors in human chorioncarcinoma cell lines

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7 January 2021

CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression

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7 January 2021

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

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7 January 2021

Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity

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7 January 2021

Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression

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7 January 2021

Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages

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7 January 2021

Involvement of ERK, p38 and NF-kappaB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells

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7 January 2021

Transcriptional regulation of lipopolysaccharide (LPS)-induced Toll-like receptor (TLR) expression in murine macrophages: role of interferon regulatory factors 1 (IRF-1) and 2 (IRF-2).

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7 January 2021

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

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7 January 2021

In vivo stimulation of CD137 broadens primary antiviral CD8+ T cell responses

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7 January 2021

Temporal segregation of 4-1BB versus CD28-mediated costimulation: 4-1BB ligand influences T cell numbers late in the primary response and regulates the size of the T cell memory response following influenza infection

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7 January 2021

Immune responses in 4-1BB (CD137)-deficient mice

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7 January 2021

Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster

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7 January 2021

Limiting inflammatory responses during activation of innate immunity

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7 January 2021

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

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7 January 2021

Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death

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7 January 2021

Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses

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7 January 2021

Determinants that control the specific interactions between TAB1 and p38alpha

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7 January 2021

Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation

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7 January 2021

Identifiers

DOI

10.1038/NI1471

1 reference

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30 December 2019

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