New insights into adipose tissue dysfunction in insulin resistance (Q37926599)

25 August 2017

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title

New insights into adipose tissue dysfunction in insulin resistance (English)

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25 August 2017

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2

Janja Marc

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25 August 2017

Barbara Mlinar

1

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25 August 2017

6 September 2011

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Clinical Chemistry and Laboratory Medicine

25 August 2017

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25 August 2017

49

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25 August 2017

1925-1935

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25 August 2017

12

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Molecular mechanisms of insulin resistance and associated diseases

25 August 2017

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance by attenuating ceramide accumulation and phosphorylation of c-Jun N-terminal kinase in peripheral tissues.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

The role of the endocannabinoid system in lipogenesis and fatty acid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Decreased lipin 1 beta expression in visceral adipose tissue is associated with insulin resistance in polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Lipin 1 gene polymorphisms in polycystic ovary syndrome.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Inflammation and metabolic disorders

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Oxidative stress, insulin signaling, and diabetes.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Signal transduction by tumor necrosis factor and its relatives

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Alterations in skeletal muscle fatty acid handling predisposes middle-aged mice to diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

The role of endoplasmic reticulum stress in the progression of atherosclerosis

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

HSP72 protects against obesity-induced insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Local adipose tissue renin-angiotensin system

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Alpha-tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Oxidative stress and diabetic complications

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Proposed mechanisms for the induction of insulin resistance by oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

The role of reactive oxygen species in insulin signaling in the vasculature

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Oxidative stress induces insulin resistance by activating the nuclear factor-kappa B pathway and disrupting normal subcellular distribution of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Uncoupling proteins, dietary fat and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through endothelial nitric oxide synthase expression in white adipocytes.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Identification of signaling pathways involved in aberrant production of adipokines in adipocytes undergoing oxidative stress

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Impact of mitochondrial reactive oxygen species and apoptosis signal-regulating kinase 1 on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

The role for endoplasmic reticulum stress in diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Inflammation in obesity is the common link between defects in fatty acid metabolism and insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Presence of functional TLR2 and TLR4 on human adipocytes

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Long-term prospective and controlled studies demonstrate adipose tissue hypercellularity and relative leptin deficiency in the postobese state

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Angiotensin II induces monocyte chemoattractant protein-1 expression via a nuclear factor-kappaB-dependent pathway in rat preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Adipose tissue, inflammation and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Evidence that low-grade systemic inflammation can induce islet dysfunction as measured by impaired calcium handling

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Relationship between blood pressure, metabolic variables and blood flow in obese subjects with or without non-insulin-dependent diabetes mellitus.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

"Vasocrine" signalling from perivascular fat: a mechanism linking insulin resistance to vascular disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Cellular hypoxia and adipose tissue dysfunction in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Impact of metformin and rosiglitazone treatment on glucose transporter 4 mRNA expression in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Adipose tissue collagen VI in obesity

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

A pericellular collagenase directs the 3-dimensional development of white adipose tissue

21 January 2018

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https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

SPARC inhibits adipogenesis by its enhancement of beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FCCLM.2011.697

21 January 2018

Identifiers

DOI

10.1515/CCLM.2011.697

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25 August 2017

1 reference

PubMed ID

21892913