p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence (Q33576299)

28 July 2017

p53 isoforms Delta133p53 and p53beta are endogenous regulators of replicative cellular senescence (English)

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28 July 2017

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Jean-Christophe Bourdon

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Jean-Christophe Bourdon

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David P. Lane

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David P Lane

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Bořivoj Vojtěšek

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Borivoj Vojtesek

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Ewy A Mathe

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Kaori Fujita

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Abdul M Mondal

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Izumi Horikawa

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Giang H Nguyen

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Kensuke Kumamoto

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Jane J Sohn

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Elise D Bowman

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Aaron J Schetter

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Sharon R Pine

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Helen Ji

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Curtis C Harris

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23 August 2009

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1135-1142

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describes a project that uses

28 July 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2802853/fullTextXML

inferred from PubMed Central ID database lookup

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2802853/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncb1928

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cites work

p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

miR-34a repression of SIRT1 regulates apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Chemokine signaling via the CXCR2 receptor reinforces senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

The MYCN oncogene is a direct target of miR-34a

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

An oncogene-induced DNA damage model for cancer development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Cellular senescence in cancer and aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

A microRNA component of the p53 tumour suppressor network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Transcriptional activation of miR-34a contributes to p53-mediated apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Surveillance mechanism linking Bub1 loss to the p53 pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

p53 isoforms can regulate p53 transcriptional activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Tumour biology: senescence in premalignant tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Ink4a/Arf expression is a biomarker of aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

TRF2 Protects Human Telomeres from End-to-End Fusions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

An amino-terminally truncated p53 protein expressed in a human choriocarcinoma cell line, CC1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Metabolism of 1,2-dimethylhydrazine by cultured human colon.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Telomere reduction in human colorectal carcinoma and with ageing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

The telomere hypothesis of cellular aging

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2802853

CDC20, a potential cancer therapeutic target, is negatively regulated by p53.

21 June 2018

1 reference

Amyloid-beta precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress.

21 January 2018

1 reference

Telomere length in the colon declines with age: a relation to colorectal cancer?

21 January 2018

1 reference

Ink4a/Arf expression is a biomarker of aging

21 January 2018

1 reference

p16(INK4a) expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19701195

12 December 2020

inferred from PubMed ID database lookup

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19701195

12 December 2020

inferred from PubMed ID database lookup

p53 downstream target genes and tumor suppression: a classical view in evolution

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19701195

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCB1928

1 reference

Dimensions Publication ID

28 July 2017

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1 reference

28 July 2017

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