Mitochondria as decision-makers in cell death (Q37704270)

22 August 2017

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title

Mitochondria as decision-makers in cell death (English)

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22 August 2017

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Vilmante Borutaite

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22 August 2017

1 June 2010

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Environmental and Molecular Mutagenesis

22 August 2017

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22 August 2017

51

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22 August 2017

5

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22 August 2017

406-416

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Free radicals in the physiological control of cell function

22 August 2017

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Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts

21 January 2018

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Interaction with substrate sensitises caspase-3 to inactivation by hydrogen peroxide.

21 January 2018

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The mitochondrial permeability transition.

21 January 2018

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Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

21 January 2018

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7 January 2021

Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death

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7 January 2021

Hydrogen peroxide inhibits caspase-dependent apoptosis by inactivating procaspase-9 in an iron-dependent manner.

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7 January 2021

Bax-type apoptotic proteins porate pure lipid bilayers through a mechanism sensitive to intrinsic monolayer curvature.

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7 January 2021

Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation

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7 January 2021

Hierarchical recruitment by AMPA but not staurosporine of pro-apoptotic mitochondrial signaling in cultured cortical neurons: evidence for caspase-dependent/independent cross-talk

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7 January 2021

On the mechanism of palmitic acid-induced apoptosis: the role of a pore induced by palmitic acid and Ca2+ in mitochondria

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7 January 2021

The permeability transition pore as a mitochondrial calcium release channel: a critical appraisal

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7 January 2021

Caspases are reversibly inactivated by hydrogen peroxide

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7 January 2021

Nitric oxide induces apoptosis via hydrogen peroxide, but necrosis via energy and thiol depletion

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7 January 2021

Mitochondrial regulation of caspase activation by cytochrome oxidase and tetramethylphenylenediamine via cytosolic cytochrome c redox state

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7 January 2021

Nitric oxide donors, nitrosothiols and mitochondrial respiration inhibitors induce caspase activation by different mechanisms.

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7 January 2021

Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia

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7 January 2021

Nitric oxide from inducible nitric oxide synthase sensitizes the inflamed aorta to hypoxic damage via respiratory inhibition

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7 January 2021

Regulation of mitochondrial membrane permeabilization by BCL-2 family proteins and caspases.

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7 January 2021

Nitric oxide and mitochondria

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7 January 2021

Regulation of apoptosis by the redox state of cytochrome c.

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7 January 2021

Mitochondrial free radical generation, oxidative stress, and aging

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7 January 2021

Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases

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7 January 2021

VDAC2 inhibits BAK activation and mitochondrial apoptosis

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7 January 2021

Role of cardiolipin alterations in mitochondrial dysfunction and disease

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7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

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7 January 2021

Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria.

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

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7 January 2021

Mitochondrial function and myocardial aging. A critical analysis of the role of permeability transition

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7 January 2021

Bcl-2 and calcium: controversy beneath the surface

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7 January 2021

Differential insult-dependent recruitment of the intrinsic mitochondrial pathway during neuronal programmed cell death

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7 January 2021

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

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7 January 2021

On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury

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7 January 2021

Nitric oxide and mitochondrial signaling: from physiology to pathophysiology.

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7 January 2021

Prothymosin-alpha1 prevents necrosis and apoptosis following stroke.

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7 January 2021

BAX activation is initiated at a novel interaction site

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7 January 2021

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

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7 January 2021

Protection by Cyclosporin A of ischemia/reperfusion-induced damage in isolated rat hearts.

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7 January 2021

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

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7 January 2021

Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

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7 January 2021

What is the mitochondrial permeability transition pore?

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7 January 2021

Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart

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7 January 2021

Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death?

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7 January 2021

Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury

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7 January 2021

Regulated and unregulated mitochondrial permeability transition pores: a new paradigm of pore structure and function?

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7 January 2021

Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.

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7 January 2021

Phospholipid asymmetry of the outer membrane of rat liver mitochondria

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7 January 2021

Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformations

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7 January 2021

Dependence of permeability transition pore opening and cytochrome C release from mitochondria on mitochondria energetic status

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7 January 2021

The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms

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7 January 2021

The Ca2+-induced membrane transition in mitochondria. III. Transitional Ca2+ release

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7 January 2021

From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state

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7 January 2021

Detergent-activated BAX protein is a monomer

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7 January 2021

"Wages of fear": transient threefold decrease in intracellular ATP level imposes apoptosis.

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7 January 2021

Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors

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7 January 2021

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

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7 January 2021

Induction of immunological tolerance by apoptotic cells requires caspase-dependent oxidation of high-mobility group box-1 protein

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7 January 2021

Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.

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7 January 2021

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system.

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7 January 2021

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

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7 January 2021

Mitochondrial membrane permeabilization in cell death

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7 January 2021

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

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7 January 2021

Inhibition of mitochondrial ATP generation by nitric oxide switches apoptosis to necrosis

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7 January 2021

Nitric oxide inhibits execution of apoptosis at two distinct ATP-dependent steps upstream and downstream of mitochondrial cytochrome c release

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7 January 2021

Cardiolipin as an oxidative target in cardiac mitochondria in the aged rat

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7 January 2021

Enhancement of cyanide-induced mitochondrial dysfunction and cortical cell necrosis by uncoupling protein-2.

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7 January 2021

Newcomers in the process of mitochondrial permeabilization

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7 January 2021

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

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7 January 2021

Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion

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7 January 2021

Mitochondria in neuroplasticity and neurological disorders

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7 January 2021

Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages

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7 January 2021

Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis

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7 January 2021

How mitochondria produce reactive oxygen species

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7 January 2021

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

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7 January 2021

Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

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7 January 2021

Mitochondrial targeting of tBid/Bax: a role for the TOM complex?

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7 January 2021

Genetic ablation of cyclophilin D rescues mitochondrial defects and prevents muscle apoptosis in collagen VI myopathic mice

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7 January 2021

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

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7 January 2021

Cardiolipin and phosphatidylglycerol are not required for the in vivo action of Bcl-2 family proteins

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7 January 2021

Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria

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7 January 2021

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death.

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7 January 2021

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

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7 January 2021

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

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7 January 2021

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

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7 January 2021

Mitochondrial ceramide and the induction of apoptosis

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7 January 2021

Bioenergetic aspects of apoptosis, necrosis and mitoptosis

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7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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7 January 2021

Suppression of the pro-apoptotic function of cytochrome c by singlet oxygen via a haem redox state-independent mechanism

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7 January 2021

Prothymosin alpha and cell death mode switch, a novel target for the prevention of cerebral ischemia-induced damage

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7 January 2021

Cell death mode switch from necrosis to apoptosis in brain

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7 January 2021

Analysis of endogenous Bax complexes during apoptosis using blue native PAGE: implications for Bax activation and oligomerization

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7 January 2021

Cigarette smoke-induced blockade of the mitochondrial respiratory chain switches lung epithelial cell apoptosis into necrosis

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7 January 2021

Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.

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7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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7 January 2021

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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7 January 2021

Mitochondrial permeability transition in apoptosis and necrosis

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7 January 2021

Identifiers

DOI

10.1002/EM.20564

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22 August 2017

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PubMed ID

20209625