Elevated production of docosahexaenoic acid in females: potential molecular mechanisms (Q37691313)

22 August 2017

1 reference

title

Elevated production of docosahexaenoic acid in females: potential molecular mechanisms (English)

1 reference

22 August 2017

Alex P Kitson

1

1 reference

PubMed ID

20151220

22 August 2017

Chad K Stroud

series ordinal

2

1 reference

PubMed ID

20151220

22 August 2017

Ken D Stark

series ordinal

3

1 reference

22 August 2017

12 February 2010

1 reference

22 August 2017

1 reference

22 August 2017

45

1 reference

22 August 2017

209-224

1 reference

22 August 2017

3

1 reference

https://scigraph.springernature.com/pub.10.1007/s11745-010-3391-6

22 August 2017

0 references

cites work

17beta-estradiol upregulates the expression of peroxisome proliferator-activated receptor alpha and lipid oxidative genes in skeletal muscle

1 reference

12 December 2020

Comparison of the peripartum and postpartum phospholipid polyunsaturated fatty acid profiles of lactating and nonlactating women

1 reference

12 December 2020

Estrogen alters spinal NMDA receptor activity via a PKA signaling pathway in a visceral pain model in the rat.

1 reference

12 December 2020

Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells

1 reference

12 December 2020

Differential cellular localization of estrogen receptor alpha in uterine and mammary cells

1 reference

12 December 2020

The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase

1 reference

12 December 2020

AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor alpha target genes

1 reference

12 December 2020

Nutritional attributes of traditional flaxseed in healthy young adults

1 reference

12 December 2020

Targeted disruption of peroxisomal proliferator-activated receptor beta (delta) results in distinct gender differences in mouse brain phospholipid and esterified FA levels

1 reference

12 December 2020

Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes

1 reference

12 December 2020

Differential eicosapentaenoic acid elevations and altered cardiovascular disease risk factor responses after supplementation with docosahexaenoic acid in postmenopausal women receiving and not receiving hormone replacement therapy.

1 reference

12 December 2020

Dietary alpha-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels.

1 reference

12 December 2020

Estradiol induces PKA activation through the putative membrane receptor in the living hippocampal neuron

1 reference

12 December 2020

Docosahexaenoic acid in red blood cells of women of reproductive age is positively associated with oral contraceptive use and physical activity.

1 reference

12 December 2020

Biosynthesis of docosahexaenoic acid in Euglena gracilis: biochemical and molecular evidence for the involvement of a Delta4-fatty acyl group desaturase

1 reference

12 December 2020

Sex differences in fatty acid composition of rat liver phosphatidylcholine are regulated by the plasma pattern of growth hormone

1 reference

12 December 2020

Raloxifene and hormone replacement therapy increase arachidonic acid and docosahexaenoic acid levels in postmenopausal women

1 reference

12 December 2020

Fish intake, contaminants, and human health: evaluating the risks and the benefits

1 reference

12 December 2020

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

1 reference

12 December 2020

17-Beta estradiol rapidly enhances extracellular signal-regulated kinase 2 phosphorylation in the rat brain

1 reference

12 December 2020

Heart estrogen receptor alpha: distinct membrane and nuclear distribution patterns and regulation by estrogen

1 reference

12 December 2020

Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL

1 reference

12 December 2020

Differences between polyunsaturated fatty acid status of non-institutionalised elderly women and younger controls: a bioconversion defect can be suspected

1 reference

12 December 2020

Membrane effects of the n-3 fish oil fatty acids, which prevent fatal ventricular arrhythmias

1 reference

12 December 2020

Sex-dependent regulation of hepatic peroxisome proliferation in mice by trichloroethylene via peroxisome proliferator-activated receptor alpha (PPARalpha)

1 reference

12 December 2020

Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases

1 reference

12 December 2020

Cloning and identification of mouse steroid receptor coactivator-1 (mSRC-1), as a coactivator of peroxisome proliferator-activated receptor gamma.

1 reference

12 December 2020

An extraordinary degree of structural specificity is required in neural phospholipids for optimal brain function: n-6 docosapentaenoic acid substitution for docosahexaenoic acid leads to a loss in spatial task performance

1 reference

12 December 2020

Effect of sex and bezafibrate on incorporation of blood borne palmitate into lipids of rat liver nuclei

1 reference

12 December 2020

Peroxisome proliferator activated receptor-alpha expression in human liver.

1 reference

12 December 2020

Identification of estrogen-responsive genes using a genome-wide analysis of promoter elements for transcription factor binding sites

1 reference

12 December 2020

Flaxseed oil increases the plasma concentrations of cardioprotective (n-3) fatty acids in humans

1 reference

12 December 2020

Effect of dietary alpha-linolenic acid on thrombotic risk factors in vegetarian men

1 reference

12 December 2020

The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin

1 reference

12 December 2020

The impact of age, body mass index, and fish intake on the EPA and DHA content of human erythrocytes.

1 reference

12 December 2020

Altered expression of fatty acid-metabolizing enzymes in aromatase-deficient mice

1 reference

12 December 2020

The enzymic chain elongation of fatty acids by rat-liver microsomes

1 reference

12 December 2020

Induction of fatty acid binding protein by peroxisome proliferators in primary hepatocyte cultures and its relationship to the induction of peroxisomal beta-oxidation

1 reference

12 December 2020

L-FABP directly interacts with PPARalpha in cultured primary hepatocytes

1 reference

12 December 2020

Tyrosine kinase/p21ras/MAP-kinase pathway activation by estradiol-receptor complex in MCF-7 cells

1 reference

12 December 2020

Gender difference in the leptin response to feeding in peroxisome-proliferator-activated receptor-alpha knockout mice

1 reference

12 December 2020

Fetal baboons convert 18:3n-3 to 22:6n-3 in vivo. A stable isotope tracer study.

1 reference

12 December 2020

Adiponectin increases fatty acid oxidation in skeletal muscle cells by sequential activation of AMP-activated protein kinase, p38 mitogen-activated protein kinase, and peroxisome proliferator-activated receptor alpha

1 reference

12 December 2020

n-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits

1 reference

12 December 2020

Sex, but not maternal protein or folic acid intake, determines the fatty acid composition of hepatic phospholipids, but not of triacylglycerol, in adult rats

1 reference

12 December 2020

Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF

1 reference

12 December 2020

S-palmitoylation modulates human estrogen receptor-alpha functions

1 reference

12 December 2020

Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects.

1 reference

12 December 2020

Leptin and phospholipid-esterified docosahexaenoic acid concentrations in plasma of women: observations during pregnancy and lactation

1 reference

12 December 2020

Regulation of the transcriptional activity of the peroxisome proliferator-activated receptor alpha by phosphorylation of a ligand-independent trans-activating domain

1 reference

12 December 2020

Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects.

1 reference

12 December 2020

Lipid-binding proteins modulate ligand-dependent trans-activation by peroxisome proliferator-activated receptors and localize to the nucleus as well as the cytoplasm.

1 reference

12 December 2020

Modulation of PPAR activity via phosphorylation

1 reference

12 December 2020

Identification of bifunctional delta12/omega3 fatty acid desaturases for improving the ratio of omega3 to omega6 fatty acids in microbes and plants

1 reference

12 December 2020

Gender differences in the n-3 fatty acid content of tissues

1 reference

12 December 2020

Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

1 reference

12 December 2020

Docosahexaenoic acid concentrations are higher in women than in men because of estrogenic effects.

1 reference

12 December 2020

Bovine brain diacylglycerol lipase: substrate specificity and activation by cyclic AMP-dependent protein kinase.

1 reference

12 December 2020

Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

1 reference

12 December 2020

Conversion of alpha-linolenic acid in humans is influenced by the absolute amounts of alpha-linolenic acid and linoleic acid in the diet and not by their ratio

1 reference

12 December 2020

Towards establishing dietary reference intakes for eicosapentaenoic and docosahexaenoic acids.

1 reference

12 December 2020

Fatty acid production in Schizochytrium sp.: Involvement of a polyunsaturated fatty acid synthase and a type I fatty acid synthase.

1 reference

12 December 2020

Methylmercury and omega-3 fatty acids: co-occurrence of dietary sources with emphasis on fish and shellfish

1 reference

12 December 2020

Activation of membrane estrogen receptors induce pro-survival kinases

1 reference

12 December 2020

Axogenic effect of estrogen in male rat hypothalamic neurons involves Ca(2+), protein kinase C, and extracellular signal-regulated kinase signaling.

1 reference

12 December 2020

G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage

1 reference

12 December 2020

Delta-6-desaturase and delta-5-desaturase in human Hep G2 cells are both fatty acid interconversion rate limiting and are upregulated under essential fatty acid deficient conditions

1 reference

12 December 2020

Effects of beef- and fish-based diets on the kinetics of n-3 fatty acid metabolism in human subjects

1 reference

12 December 2020

n-3 fatty acid metabolism in women

1 reference

12 December 2020

Essential role of Ca2+ -dependent phospholipase A2 in estradiol-induced lysosome activation

1 reference

12 December 2020

The induction of cyclooxygenase-2 (COX-2) in intact human amnion tissue by interleukin-4.

1 reference

12 December 2020

Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration

1 reference

12 December 2020

Plasma membrane estrogen receptors exist and functions as dimers

1 reference

12 December 2020

Directly quantitated dietary (n-3) fatty acid intakes of pregnant Canadian women are lower than current dietary recommendations

1 reference

12 December 2020

The effect of dietary supplements of omega 3 polyunsaturated fatty acids on the fatty acid composition of platelets and plasma choline phosphoglycerides

1 reference

12 December 2020

Comparative effect of fenofibrate on hepatic desaturases in wild-type and peroxisome proliferator-activated receptor alpha-deficient mice

1 reference

12 December 2020

Assessment of blood measures of n-3 polyunsaturated fatty acids with acute fish oil supplementation and washout in men and women

1 reference

12 December 2020

Genomic targets of nuclear estrogen receptors

1 reference

12 December 2020

Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways

1 reference

12 December 2020

Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets.

1 reference

12 December 2020

Nuclear localisation of cytosolic phospholipase A2-alpha in the EA.hy.926 human endothelial cell line is proliferation dependent and modulated by phosphorylation

1 reference

12 December 2020

Age dependence of plasma phospholipid fatty acid levels: potential role of linoleic acid in the age-associated increase in docosahexaenoic acid and eicosapentaenoic acid concentrations.

1 reference

12 December 2020

Fatty acid composition of serum phospholipid of premenopausal women and postmenopausal women receiving and not receiving hormone replacement therapy

1 reference

12 December 2020

Polyethenoid fatty acid metabolism; deposition of polyunsaturated fatty acids in fat-deficient rats upon single fatty acid supplementation

1 reference

12 December 2020

A novel peroxisome proliferator-activated receptor responsive element-luciferase reporter mouse reveals gender specificity of peroxisome proliferator-activated receptor activity in liver.

1 reference

12 December 2020

Differential expression of hepatic stearoyl-CoA desaturase gene 1 in male and female mice.

1 reference

12 December 2020

Liver type fatty acid binding protein (L-FABP) gene ablation reduces nuclear ligand distribution and peroxisome proliferator-activated receptor-alpha activity in cultured primary hepatocytes

1 reference

12 December 2020

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

1 reference

12 December 2020

Essential fatty acid transfer and fetal development

1 reference

12 December 2020

The polyunsaturated fatty acid composition of hepatic and plasma lipids differ by both sex and dietary fat intake in rats.

1 reference

12 December 2020

Thyroid hormone (T3) inhibits ciprofibrate-induced transcription of genes encoding beta-oxidation enzymes: cross talk between peroxisome proliferator and T3 signaling pathways

1 reference

12 December 2020

Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake

1 reference

12 December 2020

Mechanisms of hepatic phosphatidylcholine synthesis in adult rat: effects of pregnancy

1 reference

12 December 2020

Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women.

1 reference

12 December 2020

Distinct nongenomic signal transduction pathways controlled by 17beta-estradiol regulate DNA synthesis and cyclin D(1) gene transcription in HepG2 cells.

1 reference

12 December 2020

Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element.

1 reference

12 December 2020

Alcohol consumption in pregnant, black women is associated with decreased plasma and erythrocyte docosahexaenoic acid

1 reference

12 December 2020

Sexually dimorphic metabolism of branched-chain lipids in C57BL/6J mice

1 reference

12 December 2020

Liver fatty acid-binding protein colocalizes with peroxisome proliferator activated receptor alpha and enhances ligand distribution to nuclei of living cells

1 reference

12 December 2020

Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults

1 reference

12 December 2020

The antiarrhythmic effect of n-3 polyunsaturated fatty acids: modulation of cardiac ion channels as a potential mechanism

1 reference

12 December 2020

Activation of peroxisome proliferator-activated receptors (PPARs) by their ligands and protein kinase A activators

1 reference

12 December 2020

Engineering oilseed plants for a sustainable, land-based source of long chain polyunsaturated fatty acids

1 reference

12 December 2020

Aromatase-deficient (ArKO) mice are retrieved from severe hepatic steatosis by peroxisome proliferator administration

1 reference

12 December 2020

Are dietary recommendations for the use of fish oils sustainable?

1 reference

12 December 2020

CisView: a browser and database of cis-regulatory modules predicted in the mouse genome.

1 reference

12 December 2020

Estradiol favors the formation of eicosapentaenoic acid (20:5n-3) and n-3 docosapentaenoic acid (22:5n-3) from alpha-linolenic acid (18:3n-3) in SH-SY5Y neuroblastoma cells

1 reference

12 December 2020

Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n-3 fatty acid.

1 reference

12 December 2020

Comparison of bloodstream fatty acid composition from African-American women at gestation, delivery, and postpartum

1 reference

12 December 2020

Peroxisome proliferators alter the expression of estrogen-metabolizing enzymes

1 reference

12 December 2020

Effects of Hormone Replacement Therapy on Circulating Docosahexaenoic Acid and Eicosapentaenoic Acid Levels in Postmenopausal Women

1 reference

12 December 2020

The fatty acid profiles in a drop of blood from a fingertip correlate with physiological, dietary and lifestyle parameters in volunteers

1 reference

12 December 2020

Fatty acid biosynthesis in eukaryotic photosynthetic microalgae: identification of a microsomal delta 12 desaturase in Chlamydomonas reinhardtii

1 reference

12 December 2020

The composition of individual molecular species of plasma phosphatidylcholine in human pregnancy

1 reference

12 December 2020

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

1 reference

12 December 2020

Gender alters the effects of palmitate and oleate on fat oxidation and energy expenditure

1 reference

12 December 2020

Commercial applications of microalgae

1 reference

12 December 2020

Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals

1 reference

12 December 2020

[Studies on the metabolism of polyenoic fatty acids in the rat]

1 reference

12 December 2020

Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes

1 reference

12 December 2020

The gene encoding acyl-CoA-binding protein is subject to metabolic regulation by both sterol regulatory element-binding protein and peroxisome proliferator-activated receptor alpha in hepatocytes

1 reference

12 December 2020

Competition between 24:5n-3 and ALA for Delta 6 desaturase may limit the accumulation of DHA in HepG2 cell membranes

1 reference

12 December 2020

Dietary polyunsaturated fatty acids and hepatic gene expression

1 reference

12 December 2020

Secretory and cytosolic phospholipase A2 activities and expression are regulated by oxytocin and estradiol during labor

1 reference

12 December 2020

Dietary substitution with an alpha-linolenic acid-rich vegetable oil increases eicosapentaenoic acid concentrations in tissues

1 reference

12 December 2020

Longitudinal assessment of erythrocyte fatty acid composition throughout pregnancy and post partum.

1 reference

12 December 2020

Serum n-3 long-chain PUFA differ by sex and age in a population-based survey of New Zealand adolescents and adults

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis

1 reference

12 December 2020

Gender differences in rat erythrocyte and brain docosahexaenoic acid composition: role of ovarian hormones and dietary omega-3 fatty acid composition

1 reference

12 December 2020

Plasma omega-3 fatty acid response to a fish oil supplement in the healthy elderly

1 reference

12 December 2020

Linoleic acid-enriched phospholipids act through peroxisome proliferator-activated receptors alpha to stimulate hepatic apolipoprotein A-I secretion

1 reference

12 December 2020

Chemical control of phospholipid distribution across bilayer membranes

1 reference

12 December 2020

Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men

1 reference

12 December 2020

Gender affects liver desaturase expression in a rat model of n-3 fatty acid repletion

1 reference

12 December 2020

Conversion of alpha-linolenic acid to palmitic, palmitoleic, stearic and oleic acids in men and women

1 reference

12 December 2020

Estradiol induces proliferation of peroxisome-like microbodies and the production of 3-hydroxy fatty acid diesters, the female pheromones, in the uropygial glands of male and female mallards

1 reference

12 December 2020

Signal crosstalk between estrogen and peroxisome proliferator-activated receptor alpha on adiposity

1 reference

12 December 2020

Estrogen receptor alpha mediates the nongenomic activation of endothelial nitric oxide synthase by estrogen

1 reference

12 December 2020

Direct determinations of the fatty acid composition of daily dietary intakes incorporating nutraceuticals and functional food strategies to increase n-3 highly unsaturated fatty acids

1 reference

12 December 2020

Direct quantitation of omega-3 fatty acid intake of Canadian residents of a long-term care facility

1 reference

12 December 2020

Fatty acid composition of the red blood cell membrane in relation to menopausal status

1 reference

12 December 2020

Relations between n-3 fatty acid status and cardiovascular disease risk factors among Quebecers

1 reference

12 December 2020

Coordinate regulation of the expression of the fatty acid transport protein and acyl-CoA synthetase genes by PPARalpha and PPARgamma activators

1 reference

12 December 2020

Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium

1 reference

12 December 2020

The mechanisms of action of PPARs

1 reference

12 December 2020

Estrogen regulation of cyclin D1 gene expression in ZR-75 breast cancer cells involves multiple enhancer elements

1 reference

12 December 2020

Acinar heterogeneity of fatty acid binding protein expression in the livers of male, female and clofibrate-treated rats.

1 reference

12 December 2020

A defect in the activity of Delta6 and Delta5 desaturases may be a factor in the initiation and progression of atherosclerosis

1 reference

12 December 2020

Regulation of the biosynthesis of 4,7,10,13,16,19-docosahexaenoic acid

1 reference

12 December 2020

Dietary alpha-linolenic acid intake and risk of sudden cardiac death and coronary heart disease

1 reference

12 December 2020

Mechanisms of regulation of gene expression by fatty acids

1 reference

12 December 2020

Eicosapentaenoic and docosapentaenoic acids are the principal products of alpha-linolenic acid metabolism in young men*.

1 reference

12 December 2020

Effect of an increased intake of alpha-linolenic acid and group nutritional education on cardiovascular risk factors: the Mediterranean Alpha-linolenic Enriched Groningen Dietary Intervention (MARGARIN) study

1 reference

12 December 2020

Activation of MAPKs by 1alpha,25(OH)2-Vitamin D3 and 17beta-estradiol in skeletal muscle cells leads to phosphorylation of Elk-1 and CREB transcription factors

1 reference

12 December 2020

Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels.

1 reference

12 December 2020

A comparison of the metabolism of eighteen-carbon 13C-unsaturated fatty acids in healthy women

1 reference

12 December 2020

10.1007/S11745-010-3391-6

Identifiers

DOI

1 reference

22 August 2017

1 reference

PubMed ID

20151220