Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer. (Q37616060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170201%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer (English)

1 reference

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28 February 2020

1 reference

6

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28 February 2020

Jose M Teixeira

9

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28 February 2020

author name string

Pradeep S Tanwar

1

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28 February 2020

Gayatry Mohapatra

2

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28 February 2020

Sarah Chiang

3

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28 February 2020

David A Engler

4

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28 February 2020

Lihua Zhang

5

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28 February 2020

Yasuyo Ohguchi

7

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28 February 2020

Michael J Birrer

8

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28 February 2020

language of work or name

English

0 references

publication date

29 October 2013

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28 February 2020

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28 February 2020

volume

35

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28 February 2020

issue

3

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28 February 2020

page(s)

546-553

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Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.

28 February 2020

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Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis

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Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer

23 August 2017

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Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome

23 August 2017

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High-grade serous ovarian cancer arises from fallopian tube in a mouse model

23 August 2017

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Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

23 August 2017

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An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

23 August 2017

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Deletion of tuberous sclerosis 1 in somatic cells of the murine reproductive tract causes female infertility

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23 August 2017

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Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN

23 August 2017

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23 August 2017

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Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo.

23 August 2017

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Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer

23 August 2017

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Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder

23 August 2017

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Induction of ovarian leiomyosarcomas in mice by conditional inactivation of Brca1 and p53.

23 August 2017

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Conditional inactivation of Brca1, p53 and Rb in mouse ovaries results in the development of leiomyosarcomas

23 August 2017

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23 August 2017

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Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells

23 August 2017

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LKB1; linking cell structure and tumor suppression

23 August 2017

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23 August 2017

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23 August 2017

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A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome

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23 August 2017

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23 August 2017

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LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes

23 August 2017

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23 August 2017

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Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

6 September 2017

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14 September 2017

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14 September 2017

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14 September 2017

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25 June 2018

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Activation of mTOR signaling pathway contributes to survival of cervical cancer cells

25 June 2018

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1 September 2018

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Generation of a conditional disruption of the Tsc2 gene.

1 September 2018

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Malignant tumors of the kidney, brain, and soft tissues in children and young adults with the tuberous sclerosis complex.

1 September 2018

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1 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24170201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of mTOR signaling pathway associated with adverse prognostic factors of epithelial ovarian cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24170201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/CARCIN/BGT357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170201%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170201%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24170201%20AND%20SRC:MED&resulttype=core&format=json