GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells. (Q37544473)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15044949%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells (English)

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26 December 2019

1

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26 December 2019

5

Richard A Flavell

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26 December 2019

4

Roger J Davis

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26 December 2019

author name string

Binfeng Lu

series ordinal

2

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26 December 2019

Mutsuhiro Takekawa

series ordinal

3

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26 December 2019

language of work or name

English

0 references

publication date

25 March 2004

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26 December 2019

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26 December 2019

volume

23

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26 December 2019

issue

7

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26 December 2019

page(s)

1576-1586

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Nuclear factor of activated T cells c is a target of p38 mitogen-activated protein kinase in T cells

26 December 2019

cites work

1 reference

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Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a

23 August 2017

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STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation

23 August 2017

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23 August 2017

MAP kinase phosphatases

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Cutting edge: changes in histone acetylation at the IL-4 and IFN-gamma loci accompany Th1/Th2 differentiation

23 August 2017

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

23 August 2017

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23 August 2017

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IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.

23 August 2017

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23 August 2017

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Signal transduction by the JNK group of MAP kinases

23 August 2017

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Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution.

23 August 2017

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Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity

23 August 2017

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Gadd45 family proteins are coactivators of nuclear hormone receptors

23 August 2017

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Dual specificity phosphatases: a gene family for control of MAP kinase function.

23 August 2017

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Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

23 August 2017

1 reference

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Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

23 August 2017

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Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin

23 August 2017

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A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

23 August 2017

1 reference

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A signal transducer and activator of transcription (Stat)4-independent pathway for the development of T helper type 1 cells

23 August 2017

1 reference

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Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

23 August 2017

1 reference

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A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

23 August 2017

1 reference

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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

23 August 2017

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

23 August 2017

1 reference

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Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

23 August 2017

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Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1

23 August 2017

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Transforming growth factor-beta-induced apoptosis is mediated by Smad-dependent expression of GADD45b through p38 activation

23 August 2017

1 reference

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Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta

6 September 2017

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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.

14 September 2017

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gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress

28 September 2017

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Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

28 September 2017

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Stress-induced JNK activation is independent of Gadd45 induction

28 September 2017

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T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

25 June 2018

1 reference

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p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment

1 September 2018

1 reference

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The p38 mitogen-activated protein kinase is required for IL-12-induced IFN-gamma expression

1 September 2018

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12 December 2020

GADD45gamma mediates the activation of the p38 and JNK MAP kinase pathways and cytokine production in effector TH1 cells

1 reference

12 December 2020

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

1 reference

12 December 2020

Induction of interferon-γ production in Th1 CD4+ T cells: evidence for two distinct pathways for promoter activation

1 reference

12 December 2020

Gadd45a protects against UV irradiation-induced skin tumors, and promotes apoptosis and stress signaling via MAPK and p53

1 reference

12 December 2020

GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet

1 reference

12 December 2020

Gadd45beta is important for perpetuating cognate and inflammatory signals in T cells

1 reference

12 December 2020

Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600173

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26 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15044949%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference