A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK (Q22008047)

mitogen-activated protein kinase kinase kinase 4

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Growth arrest and DNA damage inducible beta

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Growth arrest and DNA damage inducible alpha

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c-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation

M Takekawa

1

M

Takekawa

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7 February 2023

H Saito

series ordinal

2

author given names

H

author last names

Saito

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7 February 2023

language of work or name

English

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publication date

13 November 1998

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published in

Cell

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volume

95

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page(s)

521-30

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issue

4

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cites work

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

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The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation

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The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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7 January 2021

Regulation of the activity of MEK kinase 1 (MEKK1) by autophosphorylation within the kinase activation domain

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7 January 2021

Fas-induced proteolytic activation and intracellular redistribution of the stress-signaling kinase MEKK1

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The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

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DNA damage-inducible transcripts in mammalian cells

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Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway

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Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

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Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Does the p53 up-regulated Gadd45 protein have a role in excision repair?

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p53: puzzle and paradigm

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Sounding the alarm: protein kinase cascades activated by stress and inflammation

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Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

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Specific association between the human DNA repair proteins XPA and ERCC1

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Activation of yeast PBS2 MAPKK by MAPKKKs or by binding of an SH3-containing osmosensor.

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Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cells

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Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C

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Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

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Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

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Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

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The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells

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Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen

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A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways

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Mammalian Ras interacts directly with the serine/threonine kinase Raf

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Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

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Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

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The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

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Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein

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The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

3916941

3916941

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference