Signal transduction by the JNK group of MAP kinases (Q28142592)

Gene Ontology release 2020-05-02

R J Davis

1

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publication date

13 October 2000

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language of work or name

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103

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issue

2

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page(s)

239-52

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publication type of scholarly work

review article

1 reference

Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing

Europe PubMed Central

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Regulation of JNK signaling by GSTp

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Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

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Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

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Ras and Rho GTPases: a family reunion

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Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

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7 January 2021

Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

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7 January 2021

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

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7 January 2021

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

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7 January 2021

IB1 reduces cytokine-induced apoptosis of insulin-secreting cells

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7 January 2021

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7 January 2021

The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells

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7 January 2021

Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

1 reference

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7 January 2021

Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

1 reference

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7 January 2021

Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation

1 reference

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7 January 2021

c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JNK1 is required for T cell-mediated immunity against Leishmania major infection

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

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7 January 2021

Defective T Cell Differentiation in the Absence of Jnk1

1 reference

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7 January 2021

JNK is required for effector T-cell function but not for T-cell activation

1 reference

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7 January 2021

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Stress-Induced Fas Ligand Expression in T Cells Is Mediated through a MEK Kinase 1-Regulated Response Element in the Fas Ligand Promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JNK targets p53 ubiquitination and degradation in nonstressed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

MEKK1/JNK signaling stabilizes and activates p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Stress-activated kinases regulate protein stability

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Inhibition of hypoxia/reoxygenation-induced apoptosis by an antisense oligonucleotide targeted to JNK1 in human kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Execution of Apoptosis Signal-regulating Kinase 1 (ASK1)-induced Apoptosis by the Mitochondria-dependent Caspase Activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

c-Jun is essential for normal mouse development and hepatogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Cellular transformation and malignancy induced by ras require c-jun

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

DNA Damaging Agents Induce Expression of Fas Ligand and Subsequent Apoptosis in T Lymphocytes via the Activation of NF-κB and AP-1

1 reference

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7 January 2021

A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons

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7 January 2021

ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Reduced Apoptosis and Cytochrome c–Mediated Caspase Activation in Mice Lacking Caspase 9

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Diverse functions of JNK signaling and c-Jun in stress response and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Cytochrome c deficiency causes embryonic lethality and attenuates stress-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Actin-binding protein-280 binds the stress-activated protein kinase (SAPK) activator SEK-1 and is required for tumor necrosis factor-alpha activation of SAPK in melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The mixed lineage kinase DLK utilizes MKK7 and not MKK4 as substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Interaction of c-Jun amino-terminal kinase interacting protein-1 with p190 rhoGEF and its localization in differentiated neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Planar polarity in the Drosophila eye: a multifaceted view of signaling specificity and cross-talk

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Distinct domains of mouse dishevelled are responsible for the c-Jun N-terminal kinase/stress-activated protein kinase activation and the axis formation in vertebrates.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

ASK1 is essential for JNK/SAPK activation by TRAF2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

MP1: A MEK Binding Partner That Enhances Enzymatic Activation of the MAP Kinase Cascade

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Control of cell cycle progression by c-Jun is p53 dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Role of Gadd45 in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Signal transduction by tumor necrosis factor mediated by JNK protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

SEK1/MKK4 Is Required for Maintenance of a Normal Peripheral Lymphoid Compartment but Not for Lymphocyte Development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

A conserved docking motif in MAP kinases common to substrates, activators and regulators

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Cardiac hypertrophy induced by mitogen-activated protein kinase kinase 7, a specific activator for c-Jun NH2-terminal kinase in ventricular muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

A mammalian scaffold complex that selectively mediates MAP kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Mekk3 is essential for early embryonic cardiovascular development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

The JIP group of mitogen-activated protein kinase scaffold proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

Dimerization choices control the ability of axin and dishevelled to activate c-Jun N-terminal kinase/stress-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2900116-1

7 January 2021

10.1016/S0092-8674(00)00116-1

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11057897

1 reference

Consolidated OpenCitations Corpus – April 2017