BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells (Q37399265)

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English	BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

20 August 2017

BRAF(V600E) efficient transformation and induction of microsatellite instability versus KRAS(G12V) induction of senescence markers in human colon cancer cells (English)

1 reference

Europe PubMed Central

20 August 2017

1 reference

based on heuristic

inferred from title

author name string

Eftychia Oikonomou

1

1 reference

Europe PubMed Central

20 August 2017

Eleni Makrodouli

2

1 reference

Europe PubMed Central

20 August 2017

Maria Evagelidou

3

1 reference

Europe PubMed Central

20 August 2017

Tobias Joyce

4

1 reference

Europe PubMed Central

20 August 2017

Lesley Probert

5

1 reference

Europe PubMed Central

20 August 2017

Alexander Pintzas

6

1 reference

Europe PubMed Central

20 August 2017

publication date

1 November 2009

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

11

1 reference

Europe PubMed Central

20 August 2017

1116-1131

1 reference

Europe PubMed Central

20 August 2017

11

1 reference

Europe PubMed Central

20 August 2017

Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Microsatellite instability due to hMLH1 deficiency is associated with increased cytotoxicity to irinotecan in human colorectal cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

BRAF and NRAS mutations in melanoma: potential relationships to clinical response to HSP90 inhibitors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels

1 reference

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6 September 2017

The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

BRAFE600-associated senescence-like cell cycle arrest of human naevi

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Expression of D-type cyclins in colon cancer and in cell lines from colon carcinomas

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

The RAF proteins take centre stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Guilty as charged: B-RAF is a human oncogene

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6 September 2017

Phase III double-blind placebo-controlled study of farnesyl transferase inhibitor R115777 in patients with refractory advanced colorectal cancer

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6 September 2017

The involvement of XPC protein in the cisplatin DNA damaging treatment-mediated cellular response.

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6 September 2017

The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

RAF antisense oligonucleotide as a tumor radiosensitizer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Mutations of the BRAF gene in human cancer

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6 September 2017

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

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6 September 2017

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

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6 September 2017

A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer

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6 September 2017

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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6 September 2017

Senescence of human fibroblasts induced by oncogenic Raf.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

Activated Raf-1 causes growth arrest in human small cell lung cancer cells

1 reference

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6 September 2017

Beta-catenin mutations in cell lines established from human colorectal cancers

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6 September 2017

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

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6 September 2017

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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6 September 2017

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

ras oncogenes in human cancer: a review

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

6 September 2017

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

14 September 2017

PML protein association with specific nucleolar structures differs in normal, tumor and senescent human cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

14 September 2017

In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling

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14 September 2017

Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

14 September 2017

Concomitant RASSF1A hypermethylation and KRAS/BRAF mutations occur preferentially in MSI sporadic colorectal cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2767214

14 September 2017

Pharmacologic inactivation of kinase suppressor of ras-1 abrogates Ras-mediated pancreatic cancer

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14 September 2017

Evaluation of tumor microsatellite instability using five quasimonomorphic mononucleotide repeats and pentaplex PCR.

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14 September 2017

Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products.

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28 September 2017

Molecular and functional consequences of Smad4 C-terminal missense mutations in colorectal tumour cells

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26 June 2018

Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors

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26 June 2018

Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study.

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26 June 2018

Different types of K-Ras mutations are conversely associated with overall survival in patients with colorectal cancer.

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2 September 2018

Microsatellite instability: a predictive marker in metastatic colorectal cancer?

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2 September 2018

Oncogenic potential of BRAF versus RAS.

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Barriers to Ras transformation.

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2 September 2018

A negative feedback signaling network underlies oncogene-induced senescence

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2 September 2018

Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells

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Oncogenic B-Raf mutations: crystal clear at last.

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Structural differences between valine-12 and aspartate-12 Ras proteins may modify carcinoma aggression.

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RAF/RAS oncogenes and mismatch-repair status

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Gene expression differences between the microsatellite instability (MIN) and chromosomal instability (CIN) phenotypes in colorectal cancer revealed by high-density cDNA array hybridization

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12 December 2020

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BRAF and RAS mutations in human lung cancer and melanoma

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12 December 2020

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Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

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https://pubmed.ncbi.nlm.nih.gov/19881948

12 December 2020

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p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes

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https://pubmed.ncbi.nlm.nih.gov/19881948

12 December 2020

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Phosphorylation regulates KSR1 stability, ERK activation, and cell proliferation

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12 December 2020

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Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation

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https://pubmed.ncbi.nlm.nih.gov/19881948

12 December 2020

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Identifiers

10.1593/NEO.09514

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

1 reference

Europe PubMed Central

20 August 2017

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