Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency. (Q37363074)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19759517%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency (English)

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7 February 2020

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7 February 2020

author name string

Rebecca A Marsh

2

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7 February 2020

Scott M Krummey

3

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7 February 2020

Philip Roehrs

4

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7 February 2020

Lisa R Young

5

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7 February 2020

Kejian Zhang

6

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7 February 2020

Jack van Hoff

7

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7 February 2020

Deepali Dhar

8

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7 February 2020

Kim E Nichols

9

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7 February 2020

Alexandra H Filipovich

10

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7 February 2020

Helen C Su

11

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7 February 2020

Jack J Bleesing

12

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7 February 2020

Michael J Lenardo

13

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7 February 2020

language of work or name

English

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publication date

14 September 2009

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Journal of Clinical Investigation

7 February 2020

published in

1 reference

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7 February 2020

volume

119

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7 February 2020

issue

10

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7 February 2020

page(s)

2976-2989

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The many roles of FAS receptor signaling in the immune system

7 February 2020

cites work

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6 September 2017

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A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome

6 September 2017

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Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation

6 September 2017

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NTB-A [correction of GNTB-A], a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease

6 September 2017

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Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP

6 September 2017

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The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

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Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene

6 September 2017

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6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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SAP mediates specific cytotoxic T-cell functions in X-linked lymphoproliferative disease

14 September 2017

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Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia

14 September 2017

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14 September 2017

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28 September 2017

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26 June 2018

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Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease.

2 September 2018

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Rapid detection of intracellular SH2D1A protein in cytotoxic lymphocytes from patients with X-linked lymphoproliferative disease and their family members.

2 September 2018

1 reference

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TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2752081

SAP controls T cell responses to virus and terminal differentiation of TH2 cells.

2 September 2018

1 reference

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A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.

2 September 2018

1 reference

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Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

2 September 2018

1 reference

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p63 and p73 are not required for the development and p53-dependent apoptosis of T cells

2 September 2018

1 reference

12 December 2020

Anti-CD3-stimulated Ca2+ signal in individual human peripheral T cells. Activation correlates with a sustained increase in intracellular Ca2+1

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12 December 2020

SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1

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12 December 2020

Increased proliferation of CD8+ T cells in SAP-deficient mice is associated with impaired activation-induced cell death

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12 December 2020

Cutting edge: Rac GTPases sensitize activated T cells to die via Fas

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12 December 2020

Identifiers

DOI

10.1172/JCI39518

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19759517%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19759517%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

19759517

1 reference