NMD: multitasking between mRNA surveillance and modulation of gene expression (Q37325822)

19 August 2017

1 reference

title

NMD: multitasking between mRNA surveillance and modulation of gene expression (English)

1 reference

19 August 2017

Gabriele Neu-Yilik

1

1 reference

PubMed ID

19010255

19 August 2017

Andreas E Kulozik

series ordinal

2

1 reference

19 August 2017

1 January 2008

1 reference

19 August 2017

1 reference

19 August 2017

62

1 reference

19 August 2017

185-243

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

19 August 2017

1 reference

7 January 2021

Nonsense mutations: running the red light

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A faux 3'-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

SMG-5, required for C.elegans nonsense-mediated mRNA decay, associates with SMG-2 and protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Negamycin restores dystrophin expression in skeletal and cardiac muscles of mdx mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

UPF1 is required for nonsense-mediated mRNA decay (NMD) and RNAi in Arabidopsis.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Congenital afibrinogenemia: mutations leading to premature termination codons in fibrinogen Aalpha -chain gene are not associated with the decay of the mutant mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Relationship between yeast polyribosomes and Upf proteins required for nonsense mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The double life of UPF1 in RNA and DNA stability pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The human RNA surveillance factor UPF1 is required for S phase progression and genome stability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Tissue-specific RNA surveillance? Nonsense-mediated mRNA decay causes collagen X haploinsufficiency in Schmid metaphyseal chondrodysplasia cartilage

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Quality control of gene expression: a stepwise assembly pathway for the surveillance complex that triggers nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Biochemical characterisation of cap-poly(A) synergy in rabbit reticulocyte lysates: the eIF4G-PABP interaction increases the functional affinity of eIF4E for the capped mRNA 5'-end

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

An endonuclease activity similar to Xenopus PMR1 catalyzes the degradation of normal and nonsense-containing human beta-globin mRNA in erythroid cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The human intronless melanocortin 4-receptor gene is NMD insensitive

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense mutations in the alcohol dehydrogenase gene of Drosophila melanogaster correlate with an abnormal 3' end processing of the corresponding pre-mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3' UTR length.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The 185delAG mutation (c.68_69delAG) in the BRCA1 gene triggers translation reinitiation at a downstream AUG codon

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Infrequent translation of a nonsense codon is sufficient to decrease mRNA level

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Computational modeling and experimental analysis of nonsense-mediated decay in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Identification of delta helicase as the bovine homolog of HUPF1: demonstration of an interaction with the third subunit of DNA polymerase delta

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Functional characterization in vivo of mutant p53 molecules derived from squamous cell carcinomas of the head and neck

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Correction of disease-associated exon skipping by synthetic exon-specific activators

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A nonsense mutation in the carboxyl-terminal domain of type X collagen causes haploinsufficiency in schmid metaphyseal chondrodysplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Rapid deadenylation triggered by a nonsense codon precedes decay of the RNA body in a mammalian cytoplasmic nonsense-mediated decay pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Structural and functional insights into the human Upf1 helicase core

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Cytoplasmic foci are sites of mRNA decay in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Premature termination codons enhance mRNA decapping in human cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Alternative splicing and nonsense-mediated mRNA decay regulate mammalian ribosomal gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Transcript selection and the recruitment of mRNA decay factors for NMD in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The surveillance complex interacts with the translation release factors to enhance termination and degrade aberrant mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

mRNAs encoding telomerase components and regulators are controlled by UPF genes in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

An activated 5' cryptic splice site in the human ALG3 gene generates a premature termination codon insensitive to nonsense-mediated mRNA decay in a new case of congenital disorder of glycosylation type Id (CDG-Id)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Cloning of a novel phosphatidylinositol kinase-related kinase: characterization of the human SMG-1 RNA surveillance protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Competing Functions Encoded in the Allergy-Associated FcϵRIβ Gene

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Translation is required to remove Y14 from mRNAs in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Aminoglycoside suppression of a premature stop mutation in a Cftr-/- mouse carrying a human CFTR-G542X transgene.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Telomere cap components influence the rate of senescence in telomerase-deficient yeast cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

P bodies: at the crossroads of post-transcriptional pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

In vitro properties of the conserved mammalian protein hnRNP D suggest a role in telomere maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Pre-mRNA splicing and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Ebs1p, a negative regulator of gene expression controlled by the Upf proteins in the yeast Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The Yeast Nuclear Cap Binding Complex Can Interact with Translation Factor eIF4G and Mediate Translation Initiation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Ribosome occupancy of the yeast CPA1 upstream open reading frame termination codon modulates nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Cap-binding protein 1-mediated and eukaryotic translation initiation factor 4E-mediated pioneer rounds of translation in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay in Drosophila: at the intersection of the yeast and mammalian pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Y14 and hUpf3b form an NMD-activating complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay in Saccharomyces cerevisiae: a quality control mechanism that degrades transcripts harboring premature termination codons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Impact of nonsense-mediated mRNA decay on the global expression profile of budding yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The influence of antisense oligonucleotide length on dystrophin exon skipping.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5' to 3' mRNA decay pathways in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A perfect message: RNA surveillance and nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Mechanisms of mRNA surveillance in eukaryotes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated decay approaches the clinic

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

UPF3 suppresses aberrant spliced mRNA in Arabidopsis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

CBP80 promotes interaction of Upf1 with Upf2 during nonsense-mediated mRNA decay in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Aminoglycoside antibiotics restore CFTR function by overcoming premature stop mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Readthrough of dystrophin stop codon mutations induced by aminoglycosides

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Crystal structure of the UPF2-interacting domain of nonsense-mediated mRNA decay factor UPF1.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Translation termination is involved in histone mRNA degradation when DNA replication is inhibited

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Long mutant dystrophins and variable phenotypes: evasion of nonsense-mediated decay?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Both introns and long 3'-UTRs operate as cis-acting elements to trigger nonsense-mediated decay in plants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated decay does not occur within the yeast nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

How introns influence and enhance eukaryotic gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Gene products that promote mRNA turnover in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay in mammalian cells involves decapping, deadenylating, and exonucleolytic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

eIF4G is required for the pioneer round of translation in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Yeast Upf proteins required for RNA surveillance affect global expression of the yeast transcriptome

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Telomere length regulation and telomeric chromatin require the nonsense-mediated mRNA decay pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense surveillance in lymphocytes?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay affects nonsense transcript levels and governs response of cystic fibrosis patients to gentamicin

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Stop making nonSense: the C. elegans smg genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Induced dystrophin exon skipping in human muscle explants

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Selenium deficiency reduces the abundance of mRNA for Se-dependent glutathione peroxidase 1 by a UGA-dependent mechanism likely to be nonsense codon-mediated decay of cytoplasmic mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

mRNA Metabolism and hereditary disorders: a tale of surveillance and escape

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Splicing and 3' end formation in the definition of nonsense-mediated decay-competent human beta-globin mRNPs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A quantitative analysis of intron effects on mammalian gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Inhibition of translational initiation in Saccharomyces cerevisiae by secondary structure: the roles of the stability and position of stem-loops in the mRNA leader

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Gene loops juxtapose promoters and terminators in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

mRNA surveillance by the Caenorhabditis elegans smg genes

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay factors act in concert to regulate common mRNA targets

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated mRNA decay: target genes and functional diversification of effectors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A homozygous frameshift mutation in the ESCO2 gene: evidence of intertissue and interindividual variation in Nmd efficiency.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Upf1, an RNA helicase required for nonsense-mediated mRNA decay, modulates the transcriptional response to oxidative stress in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Regulation of apoptosis by alternative pre-mRNA splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Targeting of aberrant mRNAs to cytoplasmic processing bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Cell signalling and the control of pre-mRNA splicing.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The canonical UPF1-dependent nonsense-mediated mRNA decay is inhibited in transcripts carrying a short open reading frame independent of sequence context

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Aminoglycoside-mediated suppression of nonsense mutations in late infantile neuronal ceroid lipofuscinosis

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Functional conservation of the telomerase protein Est1p in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The connection between splicing and cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Beta -Globin mRNA decay in erythroid cells: UG site-preferred endonucleolytic cleavage that is augmented by a premature termination codon

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD).

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated decay of glutathione peroxidase 1 mRNA in the cytoplasm depends on intron position

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Nonsense-mediated decay of mRNA for the selenoprotein phospholipid hydroperoxide glutathione peroxidase is detectable in cultured cells but masked or inhibited in rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

SC35 autoregulates its expression by promoting splicing events that destabilize its mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The ever-increasing complexities of the exon junction complex

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Gene set coregulated by the Saccharomyces cerevisiae nonsense-mediated mRNA decay pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Molecular basis for dominantly inherited inclusion body beta-thalassemia

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Binary specification of nonsense codons by splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Boundary-independent polar nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A quality control pathway that down-regulates aberrant T-cell receptor (TCR) transcripts by a mechanism requiring UPF2 and translation

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Does nonsense-mediated mRNA decay explain the ovarian cancer cluster region of the BRCA2 gene?

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A 3' UTR sequence stabilizes termination codons in the unspliced RNA of Rous sarcoma virus

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Messenger RNA surveillance: neutralizing natural nonsense

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Circularization of mRNA by eukaryotic translation initiation factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Exon junction complexes mediate the enhancing effect of splicing on mRNA expression

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

The cycle of nonsense

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A new function for nonsense-mediated mRNA-decay factors

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Gentamicin-Induced Correction of CFTR Function in Patients with Cystic Fibrosis andCFTRStop Mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Redirecting splicing to address dystrophin mutations: molecular by-pass surgery

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Autoregulation of polypyrimidine tract binding protein by alternative splicing leading to nonsense-mediated decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

A non-sequence-specific requirement for SMN protein activity: the role of aminoglycosides in inducing elevated SMN protein levels

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Arabidopsis UPF1 RNA helicase for nonsense-mediated mRNA decay is involved in seed size control and is essential for growth

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

Correction of CFTR malfunction and stimulation of Ca-activated Cl channels restore HCO3- secretion in cystic fibrosis bile ductular cells

1 reference

https://api.crossref.org/works/10.1016%2FS0065-2660%2808%2900604-4

7 January 2021

10.1016/S0065-2660(08)00604-4

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

19010255